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D8147
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关键词:'D8147'
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T Naqvi et al.
Peptides, 19(7), 1277-1292 (1998-10-24)
An up-to-date review is presented covering all the available information concerning the isolation, discovery, synthesis, conformation, receptor binding characteristics, pharmacological properties and SAR studies of dynorphin A and related peptides. The potential of dynorphin A and its analogs has yet
Esa R Korpi et al.
Addiction biology, 22(4), 1022-1035 (2016-03-19)
Opioid antagonist treatments reduce alcohol drinking in rodent models and in alcohol-dependent patients, with variable efficacy across different studies. These treatments may suffer from the development of tolerance and opioid receptor supersensitivity, as suggested by preclinical models showing activation of
Insights into the unique torpor of Botrylloides leachi, a colonial urochordate
Hyams Y, et al.
Developmental Biology, 428(1), 101-117 (2017)
S J Shuster et al.
Neuroscience, 96(2), 373-383 (2000-02-23)
The relationship between the cloned kappa opioid receptor, dynorphin, and the neurohypophysial hormones vasopressin and oxytocin was analysed in the guinea-pig hypothalamic magnocellular neurosecretory neurons. This analysis was performed in order to understand better which population of neuroendocrine neurons in
S Zhang et al.
The Journal of pharmacology and experimental therapeutics, 286(1), 136-141 (1998-07-10)
Dynorphin A is an endogenous opioid peptide that activates the kappa opioid receptor (KOR) with high potency. Some studies also showed that the distribution and functional activity of dynorphin A are not completely correlated with those of KOR, suggesting that
Dynorphin A selectively reduces a large transient (N-type) calcium current of mouse dorsal root ganglion neurons in cell culture
Gross R A and Macdonald R L
Proceedings of the National Academy of Sciences of the USA, 84(15), 5469-5473 (1987)
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