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E4637
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显示 1-30 #N/A 37 条结果 关于 "E4637" 范围 论文
Zhen-Yu Du et al.
Lipids, 46(7), 647-657 (2011-05-27)
Elaidic acid (trans-9-C₁₈:₁ or trans-9) is assumed to exert atherogenic effects due to its double bond configuration. The possibility that trans-9 and vaccenic acid (trans-11-C₁₈:₁ or trans-11), its positional isomer, were biochemically equivalent and interchangeable compounds, was investigated by reference
Ji-Hong Lim et al.
The Journal of biological chemistry, 288(10), 7117-7126 (2013-01-19)
Fatty acids are essential components of the dynamic lipid metabolism in cells. Fatty acids can also signal to intracellular pathways to trigger a broad range of cellular responses. Oleic acid is an abundant monounsaturated omega-9 fatty acid that impinges on
Bin Qiu et al.
Cell biology international, 36(3), 255-260 (2011-10-05)
Although TFAs (trans fatty acids) do have effects on many endothelial functions, systemic inflammation and immune disorders, only limited experimental evidence is available that TFAs participate in the pathogenesis of endothelial cell apoptosis. HUVEC (human umbilical vein endothelial cells) were
Smita P Soni et al.
Biochemistry, 48(46), 11097-11107 (2009-10-13)
We employed solid state (2)H NMR, complemented by computer simulations, to compare molecular organization in model membranes composed of 1-elaidoyl-2-stearoylphosphatidylcholine (t18:1-18:0PC), 1-oleoyl-2-stearoylphosphatidylcholine (c18:1-18:0PC), and 1,2-distearoylphosphatidylcholine (18:0-18:0PC). These phospholipids have elaidic acid (EA) containing a trans double bond, oleic acid (OA)
K B Cullberg et al.
Nutrition & diabetes, 4, e113-e113 (2014-03-26)
High levels of free fatty acids (FFA) have been suggested to be one of the underlying mechanisms for adipose tissue (AT) inflammation and dysfunction in obesity. Human AT produces several adipokines including monocyte chemoattractant protein-1 (MCP-1), which are involved in
Suzanne E Dorfman et al.
Obesity (Silver Spring, Md.), 17(6), 1200-1207 (2009-07-09)
Dietary trans-fatty acids are associated with increased risk of cardiovascular disease and have been implicated in the incidence of obesity and type 2 diabetes mellitus (T2DM). It is established that high-fat saturated diets, relative to low-fat diets, induce adiposity and
Patricia Burriel et al.
Physical review letters, 100(13), 134503-134503 (2008-06-04)
An anomalously long transient is needed to achieve a steady pressurization of a fluid when forced to flow through micronarrowed channels under constant mechanical driving. This phenomenon, known as the "bottleneck effect" is here revisited from a different perspective, by
Zhen-Yu Du et al.
Lipids, 45(7), 581-591 (2010-05-29)
Vaccenic acid (trans-11-C(18:1)) chemically resembles elaidic acid (trans-9-C(18:1)) which is assumed to increase the risk of cardiovascular diseases, and thus could exert similar effects. Possible different oxidation rates of vaccenic versus elaidic acid were checked in muscles and liver, and
Anan Yaghmur et al.
Langmuir : the ACS journal of surfaces and colloids, 28(26), 10105-10119 (2012-06-14)
In recent years, there has been a surge of interest in exploring the effect of trans-fatty acids (TFAs) on biological membrane properties. The research studies are motivated by an increasing body of evidence suggesting that the consumption of TFAs increases
Sean W P Koppe et al.
American journal of physiology. Gastrointestinal and liver physiology, 297(2), G378-G384 (2009-06-23)
Diets high in trans fats are associated with an increased risk of cardiovascular disease and components of the metabolic syndrome. The influence of these toxic fatty acids on the development of nonalcoholic fatty liver disease has not been significantly examined.
Renato Padovese et al.
The British journal of nutrition, 101(9), 1351-1359 (2008-10-03)
In the present study, the effects of trans-MUFA, elaidic acid (EA; 18 : 1-9t) and vaccenic acid (VA; 18 : 1-11t) on rat neutrophil functions were compared with those of cis-monounsaturated oleic acid (OA) (18 : 1-9c) and saturated stearic
Seddigheh Asgary et al.
Asia Pacific journal of clinical nutrition, 18(2), 187-192 (2009-08-29)
Although the disadvantages of trans fatty acids (TFAs) are widely mentioned, limited data are available on the TFAs contents of Iranian foods, including fast foods. The aim of this study was to quantify the amounts of common fatty acids in
Megan R Ruth et al.
Nutrients, 2(2), 181-197 (2010-02-01)
This study assessed the long-term effects of dietary vaccenic acid (VA) and elaidic acid (EA) on plasma and splenocyte phospholipid (PL) composition and related changes in inflammation and splenocyte phenotypes and cytokine responses in obese/insulin resistant JCR:LA-cp rats. Relative to
Gerardo Avila-Martin et al.
PloS one, 6(10), e26107-e26107 (2011-11-03)
Sensorimotor dysfunction following incomplete spinal cord injury (iSCI) is often characterized by the debilitating symptoms of paralysis, spasticity and pain, which require treatment with novel pleiotropic pharmacological agents. Previous in vitro studies suggest that Albumin (Alb) and Oleic Acid (OA)
Erika Cecon et al.
Cell chemical biology (2021-07-12)
Targeting the interaction between the SARS-CoV-2 spike protein and human ACE2, its primary cell membrane receptor, is a promising therapeutic strategy to prevent viral entry. Recent in vitro studies revealed that the receptor binding domain (RBD) of the spike protein plays
Toke Peter Krogager et al.
Journal of proteomics, 75(9), 2685-2696 (2012-04-10)
Trans fatty acid intake has been correlated to an unfavorable plasma lipoprotein profile and an increased cardiovascular disease risk. The present study aimed to identify a plasma protein biomarker panel related to human intake of elaidic acid. The human liver
Véronique Chajès et al.
American journal of epidemiology, 167(11), 1312-1320 (2008-04-09)
The authors assessed the association between serum phospholipid fatty acids as biomarkers of fatty acid intake and breast cancer risk among women in the E3N Study (1989-2002), the French component of the European Prospective Investigation into Cancer and Nutrition. During
Bodo Brueckner et al.
Molecular cancer therapeutics, 9(5), 1256-1264 (2010-05-06)
Azacytidine is an established nucleoside drug that is well known for its ability to modulate epigenetic gene regulation by inhibition of DNA methylation. Despite recent advances in the clinical development of azacytidine, the use of the drug is limited by
Véronique Chajès et al.
Nutrition and cancer, 63(8), 1235-1250 (2011-11-03)
Elaidic acid is the main unnatural trans fatty acid isomer occurring during partial hydrogenation of vegetable oils used as ingredients for the formulation of processed foods. The main objective is to assess associations between processed food intakes and plasma phospholipid
Jian-xin Zhang et al.
Toxicology and industrial health, 26(8), 469-477 (2010-06-18)
Acrylamide (ACR) and trans fatty acids (TFA) could be found co-existent in many foods processed by high temperature. Our study investigated effect of elaidic acid (ELA), the predominant TFA, on deficits of spermatogenesis induced by ACR. Results showed that ELA
Ewa Stachowska et al.
European journal of nutrition, 43(5), 313-318 (2004-08-17)
Dietary fatty acids are incorporated into atheromatous plaques mainly in the form of cholesterol esters. Physicochemical properties of the plaque (e. g. mechanical strength) depend on its fatty acid composition. Trans isomers of unsaturated fatty acids (TFA) are known to
Guangling Jiao et al.
Marine drugs, 13(6), 3849-3876 (2015-06-23)
Northern shrimp (Pandalus borealis) oil, which is rich in omega-3 fatty acids, was recovered from the cooking water of shrimp processing facilities. The oil contains significant amounts of omega-3 fatty acids in triglyceride form, along with substantial long-chain monounsaturated fatty
Nuria Granados et al.
The British journal of nutrition, 105(8), 1226-1234 (2011-01-07)
Trans-fatty acids (TFA) and cis-monounsaturated fat appear to exert detrimental and beneficial effects, respectively, on glucose metabolism and insulin sensitivity. Adipose tissue and skeletal muscle are a source of signalling proteins (adipokines and myokines), some of which have been related
Huawei Zeng et al.
Nutrition and cancer, 67(5), 831-838 (2015-05-27)
Data indicate that methylselenol is a critical selenium (Se) metabolite for anticancer activity in vivo. We tested the hypothesis that oral dosing methylseleninic acid (MSeA), a methylselenol precursor, inhibits the growth of colon cancer xenografts in C57BL/6 mice fed a
Guan-yuan Chen et al.
Clinica chimica acta; international journal of clinical chemistry, 438, 126-134 (2014-08-26)
As fatty acids play an important role in biological regulation, the profiling of fatty acid expression has been used to discover various disease markers and to understand disease mechanisms. This study developed an effective and accurate comparative fatty acid analysis
Jaeho Ha et al.
Talanta, 85(1), 252-258 (2011-06-08)
Trans fatty acids (TFAs) are present in meat and dairy products as m ruminant animals and in vegetable fats due to partial hydrogenation. This study aimed to discriminate between natural (N-TFA) and hydrogenated trans fatty (H-TFA) acids by GC×GC-flame ionization
Natalie Fournier et al.
Biochimica et biophysica acta, 1821(2), 303-312 (2011-11-15)
Consumption of trans fatty acids (TFA) increase cardiovascular risk more than do saturated FA, but the mechanisms explaining their atherogenicity are still unclear. We investigated the impact of membrane incorporation of TFA on cholesterol efflux by exposing J774 mouse macrophages
Influence of the sophorolipid molecular geometry on their self-assembled structures.
Prabhu Dhasaiyan et al.
Chemistry, an Asian journal, 8(2), 369-372 (2012-12-05)
Dynamic molecular behavior of semi-fluorinated oleic, elaidic and stearic acids in the liquid state.
Shun Yamamoto et al.
Journal of oleo science, 61(11), 649-657 (2012-11-10)
Ordinary fatty acids such as oleic, elaidic and stearic acids exist as their hydrogen-bonded dimers in their liquids and in non-polar solvents. Infrared (IR) and nuclear magnetic resonance (NMR) spectroscopy have revealed that semi-fluorinated (SF) acids containing a perfluorooctyl group
Xiao-Ping Li et al.
Lipids, 48(4), 395-403 (2013-01-24)
Trans fatty acids (TFA) have been considered as an independent risk factor of coronary heart disease, sudden death and insulin-resistance, and different TFA isomers may have different effects on the progression of cardiovascular diseases such as atherosclerosis. The aim of
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