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关键词:'extran'
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Yujie Yang et al.
The AAPS journal, 19(6), 1791-1803 (2017-08-30)
Protein losing enteropathy (PLE), which is characterized by substantial loss of plasma proteins into the gastrointestinal (GI) tract, is a complication of a variety of GI diseases, including inflammatory bowel disease. Clinical studies have found that the clearance of monoclonal
Mingxiang Lin et al.
Journal of pharmaceutical and biomedical analysis, 45(5), 747-755 (2007-10-12)
During the content uniformity test of a drug product (tablet formulation), an unknown peak was observed in the HPLC chromatograms. Upon further investigation, it was determined that the unknown peak was originated from an external source and, therefore, the drug
Xiao-peng Han et al.
Zhonghua wai ke za zhi [Chinese journal of surgery], 47(18), 1415-1418 (2010-01-23)
To investigate the effects of TNF-alpha, TNF-beta and the acceptor expression about mechanical renal trauma with extraneous ADM. There were 104 healthy adult plain grade Wistar rat, randomly divided into four groups:8 in the group of control, 32 in the
B Fredricsson et al.
Gynecologic and obstetric investigation, 9(5), 268-276 (1978-01-01)
Variation in urinary excretion of estriol was found to be related to physical activity and climate conditions. Estriol content of sweat was studied but was found not to be of an order to explain the variation observed. Estriol clearance rate
C J Morrison et al.
Journal of general microbiology, 139 Pt 6, 1177-1186 (1993-06-01)
Aspartyl proteinase (AP) is an extracellular enzyme of Candida albicans implicated as a pathogenic factor. Previous reports on the purification and characterization of AP suggested that a single DEAE-Sephadex chromatographic step was sufficient for the removal of extraneous proteins and
Navneet Kaur et al.
Carbohydrate polymers, 237, 116170-116170 (2020-04-04)
Poly (lactide-co-glycolide) (PLGA) nanoparticles surface functionalized with water soluble glycol chitosan (GC) and carboxymethyl chitosan (CMC) has been studied for their drug (Paclitaxel and Doxorubicin) loading, yield, cellular uptake, serum protein adsorption and hemocompatibility. It was observed that Paclitaxel (Ptxl)
E T Schenborn et al.
Nucleic acids research, 13(17), 6223-6236 (1985-09-11)
The in vitro synthesis of extraneous RNA sequences by SP6 and T7 RNA polymerases from specific DNA templates is described. Transcription of templates prepared by digestion with restriction enzymes that leave 3' protruding ends resulted in the production of significant
N C Jain et al.
Journal of forensic sciences, 22(1), 7-16 (1977-01-01)
A gas chromatographic procedure has been developed for the simultaneous determination of cocaine and benzoyl ecgonine in urine specimens. The two drugs are extracted by isopropanol/chloroform from urine samples saturated with a bisalt buffer. The organic extract is evaporated to
Li-qun Zhang et al.
Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases, 28(5), 333-336 (2005-06-14)
To investigate the inhibition effects of fragile histidine triad (FHIT) gene on the malignant growth of A549 cell line. A mammalian expression vector PEGFP-FHIT was constructed and transfected into the A549 cell line by lipofectamine. Then the transfected cell line
Kevin C Miranda et al.
Kidney international, 78(2), 191-199 (2010-04-30)
Urinary exosomes or microvesicles are being studied intensively to identify potential new biomarkers for renal disease. We sought to identify whether these microvesicles contain nucleic acids. We isolated microvesicles from human urine in the same density range as that previously
Weiguang Zeng et al.
Vaccine, 33(30), 3526-3532 (2015-06-07)
The highly conserved extracellular domain of Matrix protein 2 (M2e) of influenza A virus has been previously investigated as a potential target for an universal influenza vaccine. In this study we prepared four lipopeptide influenza vaccine candidates in which the
Suvash Chandra Ojha et al.
Protein expression and purification, 151, 106-112 (2018-06-27)
Lysostaphin, a bacteriolytic toxin from Staphylococcus simulans, is a Zn2+-dependent endopeptidase that cleaves pentaglycine cross-bridges found in peptidoglycan of certain Staphylococci. Here, we have investigated a critical influence of Zn2+ ions on lysostaphin-induced bioactivity. Initially, we succeeded in producing a
V Pirrotta
BioEssays : news and reviews in molecular, cellular and developmental biology, 12(9), 409-414 (1990-09-01)
Numerous genes contain regulatory elements located many tens of kilobases away from the promoter they control. Specific mechanisms must be required to ensure that such distant elements can find and interact with their proper targets but not with extraneous genes.
P S Baur et al.
Journal of microscopy, 109(3), 315-327 (1977-04-01)
PIPES, an organic based buffer, was used in the preparation of a variety of marine and mammalian tissues for electron microscopic study. The ultrastructural results demonstrate that this buffer renders superior ultrastructural details to those obtained with some of the
Beatrice Vignoli et al.
Cells, 11(9) (2022-05-15)
Neurons release and respond to brain-derived neurotrophic factor (BDNF) with bursts of brain activity. BDNF action is known to extend to peri-synaptic astrocytes, contributing to synaptic strengthening. This implies that astrocytes have a set of dynamic responses, some of which
Zhi Xu et al.
Electrophoresis, 30(8), 1282-1285 (2009-03-19)
Much attention has been paid on ancient DNA (aDNA) studies, and negative control was used as one of the stringent quality assurance criteria in order to detect potential contamination. However, the results of some aDNA studies showed the evidence of
Y Huang et al.
Development (Cambridge, England), 122(10), 3207-3216 (1996-10-01)
The Drosophila compound eye develops by a complex series of cell interactions where multiple positive and inhibitory cues guide cells in each facet into their positions and fates. The results of many genetic and molecular experiments have led to the
Ian Dworkin
Evolution; international journal of organic evolution, 59(7), 1500-1509 (2005-09-13)
Among the explanations for minimizing the effects of extraneous variation has been canalization and developmental stability. However, there is little agreement as to whether these two processes reflect a common set of mechanisms. This confusion is inflated due to the
Carl F Ware et al.
Current opinion in immunology, 23(5), 627-631 (2011-09-17)
The herpesvirus entry mediator (HVEM; TNFRSF14) can activate either proinflammatory or inhibitory signaling pathways. HVEM engages two distinct types of ligands, the canonical TNF-related cytokines, LIGHT and Lymphotoxin-α, and the Ig-related membrane proteins, BTLA (B and T lymphocyte attenuator) and
J R Petersen et al.
Journal of chromatography. A, 744(1-2), 37-44 (1996-09-13)
Most of the procedures currently performed by capillary zone electrophoresis (CZE) with laser induced fluorescence detection requires prior derivatization. This increases cost, the turn-around-time and chances of extraneous contaminations. CZE with laser induced resonance energy transfer is demonstrated as a
Sonoko Hasegawa et al.
Molecular and cellular neurosciences, 38(1), 66-79 (2008-03-21)
Olfactory sensory neurons (OSNs) that express the same odorant receptor project their axons to specific glomeruli in the main olfactory bulb. Protocadherin-alpha (Pcdha) proteins, diverse cadherin-related molecules that are encoded as a gene cluster, are highly concentrated in OSN axons
Marisa N Madison et al.
Bio-protocol, 7(7) (2017-07-01)
Exosomes are membranous extracellular nanovesicles of endocytic origin. Exosomes are known to carry host and pathogen-derived genomic, proteomic, lipidomic cargos and other extraneous molecules. Exosomes are secreted by diverse cell types into the extracellular milieu and are subsequently internalized by
Hiroshi Kitagaki et al.
Annual review of food science and technology, 4, 215-235 (2013-03-08)
Sake is an alcoholic beverage of Japan, with a tradition lasting more than 1,300 years; it is produced from rice and water by fermenting with the koji mold Aspergillus oryzae and sake yeast Saccharomyces cerevisiae. Breeding research on sake yeasts
R C Cheung et al.
Journal of clinical microbiology, 32(10), 2593-2597 (1994-10-01)
We describe a rapid, sensitive, and economic method for detection of hepatitis C virus (HCV) RNA. This method uses silica particles for purification of nucleic acid and then a modified reverse transcription-PCR that minimizes the risk of contamination and reduces
Anthony A Chariton et al.
Environmental pollution (Barking, Essex : 1987), 203, 165-174 (2015-04-25)
DNA-derived measurements of biological composition have the potential to produce data covering all of life, and provide a tantalizing proposition for researchers and managers. We used metabarcoding to compare benthic eukaryote composition from five estuaries of varying condition. In contrast
Roya Elaine Haghighat-Khah et al.
PloS one, 10(4), e0121097-e0121097 (2015-04-02)
Genetically engineered insects are being evaluated as potential tools to decrease the economic and public health burden of mosquitoes and agricultural pest insects. Here we describe a new tool for the reliable and targeted genome manipulation of pest insects for
Stella A Ordoudi et al.
Food chemistry, 267, 410-419 (2018-06-24)
The stepwise approach takes advantage of simple, versatile, low-cost screening tools that can be applied to several posts of the saffron trade chain to specifically detect adulteration with carminic acid (CA). This natural dye is of insect origin and should
N M Bonini et al.
BioEssays : news and reviews in molecular, cellular and developmental biology, 21(12), 991-1003 (1999-12-02)
Normal differentiation requires an appropriately orchestrated sequence of developmental events. Regulation of cell survival and cell death is integrated with these events to achieve proper cell number, cell type, and tissue structure. Here we review regulation of cell survival in
Mohammad Shariq et al.
Science advances, 7(21) (2021-05-23)
Inflammation is known to adversely affect adult neurogenesis, wherein the source of inflammation is largely thought to be extraneous to the neurogenic niche. Here, we demonstrate that the adult hippocampal neural progenitors harbor an inflammatory potential that is proactively suppressed
B A Tomkins et al.
Journal of chromatography. A, 911(1), 85-96 (2001-03-28)
A highly sensitive analytical procedure is described for determining thiodiglycol in groundwater. Samples are initially fortified with 3,3'-thiodipropanol (surrogate), then both species are extracted using sequential solid-phase extraction with both C18 and Ambersorb 572 columns. The C18 column, which removes
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