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Min-Sang Yoo et al.
Food chemistry, 135(3), 967-975 (2012-09-08)
It has been reported that fucosterol has anti-diabetic, anti-oxidant, and anti-osteoporotic effects. We investigated the anti-inflammatory effects and the underlying molecular mechanism of fucosterol in lipopolysaccharide (LPS)-induced RAW 264.7 macrophages. Fucosterol suppressed the expressions of inducible nitric oxide synthase (iNOS)
Yeon Sil Lee et al.
Archives of pharmacal research, 27(11), 1120-1122 (2004-12-15)
Fucosterol isolated from Pelvetia siliquosa was tested for its anti-diabetic activity in vivo. Fucosterol, when administered orally at 30 mg/kg in streptozotocin-induced diabetic rats, was caused a significant decrease in serum glucose concentrations, and exhibited an inhibition of sorbitol accumulations
M D'Agostino et al.
Bollettino della Societa italiana di biologia sperimentale, 60(12), 2241-2245 (1984-12-30)
The sterol fraction of Equisetum arvense L. contains, essentially, the following sterols: beta-sitosterol (60.0%), campesterol (32.9%), isofucosterol (5.9%) and cholesterol (trace amounts). The identification of the compounds has been carried out through NMR and MS, while the corresponding percentage have
Meiko Ito et al.
Food chemistry, 255, 147-156 (2018-03-25)
The functional chemical substances and the antioxidant activity of lipids in 21 marine algae along the Japanese coast were investigated. Principal component analysis was performed to detect any correlation between the chemical substances and algae phylum. Chlorophyta contained a high
Dirk Umlauf et al.
Phytochemistry, 65(17), 2463-2470 (2004-09-24)
The incorporation of [1-13C]-labeled glucose into the irregular monoterpene artemisia ketone, the regular monoterpenes camphor and beta-thujone, the sesquiterpene germacrene D, the diterpene trans-phytol and beta-sitosterol and isofucosterol has been studied in axenic cultures of Tanacetum vulgare L. (Asteraceae). Quantitative
Fu-Hang Song et al.
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 31(2), 125-128 (2006-03-31)
To investigate the chemical constituents of the brown alga D. divaricata, and to test cytotoxicities of the purified compounds. Compounds were isolated by normal phase silica gel, Sephadex LH-20 chromatography and reverse phase HPLC techniques. Their structures were elucidated by
S Kojima et al.
Bioscience reports, 6(12), 1029-1033 (1986-12-01)
We have succeeded in corroborating the enhancing effect of vitamin A, vitamin C, sitosterol and fucosterol on the fibrinolytic activity of endothelial cells. The assay system consisted of an in situ dissolution of a fibrin layer coated onto a culture
Zhangfan Mao et al.
Phytomedicine : international journal of phytotherapy and phytopharmacology, 61, 152809-152809 (2019-04-30)
Phytochemicals have attained tremendous attention as the chemo-preventive and chemotheruptic agents. Fucosterol is a phytosterol that in prevalently found in marine algae and many other plant species. Previous studies have indicated the potential of fucosterol as an anticancer agent. However
Cassandra D Kinch et al.
Aquatic toxicology (Amsterdam, Netherlands), 175, 286-298 (2016-04-24)
Exposure to environmental contaminants has been linked to developmental and reproductive abnormalities leading to infertility, spontaneous abortion, reduced number of offspring, and metabolic disorders. In addition, there is evidence linking environmental contaminants and endocrine disruption to abnormal developmental rate, defects
Hui-Xia Geng et al.
Harmful algae, 66, 29-39 (2017-06-13)
Sterols, a group of stable lipid compounds, are often used as biomarkers in marine biogeochemical studies to indicate sources of organic matter. In this study, sterols in 13 species of major bloom-forming algae in China, which belong to Dinophyceae, Bacillariophyceae
Ji-Hyun Lee et al.
The Journal of pharmacy and pharmacology, 69(3), 325-333 (2017-01-31)
The purpose of this study was to investigate the effects of fucosterol on adipogenesis of 3T3-L1 preadipocytes and its underlying mechanisms. Fucosterol, isolated from brown algae, Ecklonia stolonifera. We investigated the levels of lipid accumulation using Oil Red O staining.
Genoveffa Nuzzo et al.
Marine drugs, 17(1) (2018-12-28)
Diatoms are unicellular eukaryotic organisms that play a key ecological and biogeochemical role in oceans as major primary producers. Recently, these microalgae have also attracted interest as a promising source of functional products with widespread relevance. Progress in the knowledge
Su-Qiu Pang et al.
Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 32(8), 1229-1231 (2009-12-08)
To study the chemical constituents of Fructus Broussonetiae. Column chromatography with silic gel was employed to isolate and purify the 80% alcohol extract of Fructus Broussonetia, and the constituents were identified by spectral methods. Six compounds were isolated from 80%
H Hagiwara et al.
Biochemical and biophysical research communications, 139(1), 348-352 (1986-08-29)
The modulation of angiotensin converting enzyme (ACE) levels was studied using fucosterol, one of phytosterols, in cultured bovine carotid endothelial cells. Addition of fucosterol to the culture medium resulted in the decrease of ACE activity of endothelial cells; however, fucosterol
F Acartürk et al.
The Journal of pharmacy and pharmacology, 45(12), 1028-1032 (1993-12-01)
The complexation of fucosterol with three kinds of beta-cyclodextrin (beta-CyD) was investigated in aqueous solution and in the solid state. The solubility of fucosterol increased significantly on its complexation with maltosyl-beta-CyD and heptakis(2,6-di-O-methyl)-beta-CyD (DM-beta-CyD), while no appreciable increase was observed
Effects of Ecklonia arborea or Silvetia compressa algae intake on serum lipids and hepatic fat accumulation in Wistar rats fed hyperlipidic diets
Laura AP, et al.
Algal research null
Nina S Liland et al.
Lipids, 53(7), 737-747 (2018-09-28)
Several feeding trials with Atlantic salmon fed naturally high phytosterol concentrations due to dietary rapeseed oil inclusion have shown changes in lipid metabolism and increased hepatic lipid storage in the fish. An in vitro trial with Atlantic salmon hepatocytes was
M C Dai et al.
Chemistry and physics of lipids, 59(3), 245-253 (1991-10-01)
The thermotropic behavior of multilamellar vesicles (MLV) composed of different mole fractions of various marine sterols and 1-stearoyl-2-oleoyl phosphatidylcholine (SOPC) was examined by differential scanning calorimetry (DSC), and was compared to pure SOPC as well as their mixtures with cholesterol.
Sang-Yong Park et al.
Marine biotechnology (New York, N.Y.), 19(1), 65-75 (2017-02-01)
Hizikia fusiforme, a brown seaweed, has been utilized as a health food and in traditional medicine. In this study, we investigated whether enzyme-modified H. fusiforme extracts (EH) have immunological effects compared with normal H. fusiforme extracts (NH). The effects of
I P Shanura Fernando et al.
Environmental research, 172, 150-158 (2019-02-21)
Particulate matter (PM) air pollution has gradually become a widespread problem in East Asia. PM may cause unfamiliar inflammatory responses, oxidative stress, and pulmonary tissue damage, and a comprehensive understanding of the underlying mechanisms is required in order to develop
Paul Dahlin et al.
PloS one, 12(2), e0170873-e0170873 (2017-02-06)
The oomycete class includes pathogens of animals and plants which are responsible for some of the most significant global losses in agriculture and aquaculture. There is a need to replace traditional chemical means of controlling oomycete growth with more targeted
A Kamal-Eldin et al.
Lipids, 33(11), 1073-1077 (1998-12-31)
This work shows that fucosterol, delta5-avenasterol, and similar ethylidene-side chain sterols can undergo acid-catalyzed isomerization to give a mixture of five isomers. Four isomers formed from fucosterol were analyzed, using gas chromatography-mass spectrometry, and were characterized as delta5-avenasterol, two delta5,23-stigmastadienols
M Rohmer et al.
Steroids, 35(2), 219-231 (1980-02-01)
Two new sterols, (24E)-24-n-propylidenecholesterol and 24 epsilon-n-propylcholesterol, were isolated from a cultured marine Chrysophyte. Since most of the steroids found in marine invertebrates are unchanged or modified sterols of algal or symbiotic origin, the discovery of these two unusual sterols
Nicolas Panayotis et al.
Cell reports. Medicine, 2(5), 100281-100281 (2021-06-08)
Anxiety and stress-related conditions represent a significant health burden in modern society. Unfortunately, most anxiolytic drugs are prone to side effects, limiting their long-term usage. Here, we employ a bioinformatics screen to identify drugs for repurposing as anxiolytics. Comparison of
Alice A Ramos et al.
Journal of toxicology and environmental health. Part A, 82(9), 537-549 (2019-07-02)
Colorectal cancer (CRC) is one of the most frequently occurring carcinomas which require effective therapies. Fucosterol is a sterol present in marine brown seaweeds with several biological activities. However, the influence of fucosterol in CRC remains to be determined. Thus
Sanghyun Lee et al.
Archives of pharmacal research, 26(9), 719-722 (2003-10-17)
The anti-oxidant activities of fucosterol isolated from the marine algae Pelvetia siliquosa were investigated. Fucosterol exhibited a significant decrease in serum transaminase activities elevated by hepatic damage induced by CCl4-intoxication in rats. Fucosterol inhibited the sGOT and sGPT activities by
B C Sekula et al.
Lipids, 16(3), 195-198 (1981-03-01)
Anaerobically grown Saccharomyces cerevisiae retained the ability to transfer a C1-group to the C-24 position of a delta 24(25)-sterol and to reduce the delta 25(28)-bond of a 24-methylenesterol. Both desmosterol and 24-methylenecholesterol yielded 24 beta-methylcholesterol. However, when the substituent at
I Ikeda et al.
Journal of lipid research, 29(12), 1573-1582 (1988-12-01)
The extent and site(s) of inhibition of cholesterol absorption by plant sterols, sitosterol and fucosterol, were studied in rats. The intragastric administration of a single emulsified lipid meal containing 25 mg [3H]cholesterol and 25 mg of either sitosterol or fucosterol
Arnaud Belcour et al.
iScience, 23(2), 100849-100849 (2020-02-15)
Inferring genome-scale metabolic networks in emerging model organisms is challenged by incomplete biochemical knowledge and partial conservation of biochemical pathways during evolution. Therefore, specific bioinformatic tools are necessary to infer biochemical reactions and metabolic structures that can be checked experimentally.
Cassandra D Kinch et al.
Aquatic toxicology (Amsterdam, Netherlands), 175, 286-298 (2016-04-24)
Exposure to environmental contaminants has been linked to developmental and reproductive abnormalities leading to infertility, spontaneous abortion, reduced number of offspring, and metabolic disorders. In addition, there is evidence linking environmental contaminants and endocrine disruption to abnormal developmental rate, defects
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