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Protein expression
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facet applications:Protein expression
facet content type:Technical Article
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丝裂原活化蛋白激酶(MAPK)
丝裂原活化蛋白激酶(MAPK)家族由应激激活(SAPK)和丝裂原活化(MAPK)的蛋白激酶组成。了解它们介导细胞多种刺激反应的信号转导级联网络。
表皮生长因子受体 (EGFR) 信号传导
阅读有关EGF / EGFR信号传导（表皮生长因子受体）的评论，并找到相关产品的链接
多巴胺及去甲肾上腺素代谢
单胺氧化酶A（MAO）或儿茶酚-O-甲基转移酶（COMT）均可对儿茶酚胺分解代谢的第一步进行催化。在MAO反应中所产生的具有潜在毒性的醛中间体（多巴胺的3,4-二羟基苯乙醛，3去甲肾上腺素的4-二羟基苯基乙醛用于）会被迅速还原为醇（通过细胞溶质醛还原酶或醛糖还原酶）或被氧化成酸（通过线粒体醛脱氢酶）。
一氧化氮合酶
我们针对客户的研究需求，提供了许多一氧化氮合酶相关的产品。
核受体（类固醇）
我们可提供多种核受体（类固醇）相关产品，满足您的各类研究需求。
无细胞蛋白合成或表达
无细胞蛋白合成或表达 (CFPE) 是一种合成生物学方法，无需细胞参与即可在溶液中快速生产重组蛋白质。研究人员可使用从一系列不同类型细胞中提取的生物分子翻译机器，在一天内表达目标蛋白质。
组胺受体
我们提供多种与组胺受体相关的产品，以满足您的各类研究需求。
血清素受体
我们提供许多血清素受体相关产品，满足您的各类研究需求。
阿片受体
我们可提供多种与阿片受体相关的产品，以满足您的各类研究需求。
磷脂酶A2
磷脂酶A2（PLA2）代表的是一类可水解甘油磷脂的sn-2酯以产生脂肪酸和溶血磷脂的酶。目前已知的是，其中一些酶可在哺乳动物细胞中释放花生四烯酸以用于类花生酸的生物合成，因此PLA2抑制剂的开发引起了相当大的兴趣。基于氨基酸序列，现有超过12种不同的哺乳动物PLA2以及多种非哺乳动物的形式，它们被归类为具有多个亚组的14个组别。
FLAG®标记细菌和哺乳动物表达载体
FLAG®和3xFLAG®表达载体和产品用于细菌和哺乳动物表达载体以及蛋白质检测和纯化。
钙通道
我们提供多种与钙通道相关的产品以满足您的各类研究需求。
An ECM Mimetic Library for Engineering Surfaces to Direct Cell Surface Receptor Binding Specificity and Signaling
The extracellular (ECM) microenvironment, defined by biochemical cues and physical cues, is a deciding factor in a wide range of cellular processes including cell adhesion, proliferation, differentiation, and expression of phenotype-specific functions. For this reason, engineering the ECM microenvironment provides
Sensor Dyes
Nitric oxide (NO) as a signal transporter in neurons, endothelial cells and in the immune system.
VEGF Pathway
Read review on VEGF signaling pathway (Vascular endothelial growth factor (VEGF)/VEGF receptor) and find related products.
Protein Expression Systems
The development of genetic engineering and cloning has opened many possibilities of expression and isolation of heterologous proteins for research purposes. Considerable advances in technology have enabled expression and isolation of recombinant proteins in large scale.
Calcitonin Gene-Related Peptides
Sigma-Aldrich offers many products related to calcitonin gene-related peptides for your research needs.
Utilizing ISOGRO® Supplementation of M9 Minimal Media to Enhance Recombinant Protein Expression
Utilizing ISOGRO® Supplementation of M9 Minimal Media to Enhance Recombinant Protein Expression.
p53: DNA Damage Response and Cancer
p53 regulates gene expression, cell cycle control and functions as a tumor suppressor. Inactivation of p53 is closely tied to cancer development.
Cloning & Expression Vectors
Expression Vectors for Bacterial, Mammalian and Insect Cell Systems. Featured are a variety of tags, promoters and elements for secretion, transient, stable and bicistronic expression.
MISSION shRNA Lentiviral Transduction
MISSION® shRNA Lentiviral Transduction application data
Duolink® PLA Technology for Neuroscience Applications
Duolink® proximity ligation assay used to study neuron interactions furthering neuroscience research.
Studies of Dimerization and Activation of Receptors in the EGFR-Family Using Duolink® Assays
Our aim was to investigate the dimerization and activation pattern of two receptors, EGFR (ErbB1) and HER2 (ErbB2), in the EGFR-family using breast cancer cell lines and selected colon tissues as model systems.
Lipid-induced Insulin Resistance
Lipid Induced Insulin Resistance
NF-κB and Inflammation
Chronic inflammation is an underlying factor in the development and progression of many of the chronic diseases of aging, such as arthritis, atherosclerosis, diabetes, and cancer.
Dietary Antioxidants
Antioxidants protect biological systems from oxidative damage produced by oxygen-containing free radicals and from redoxactive transition metal ions such as iron, copper, and cadmium.
Signal Peptide Optimization: Effect On Recombinant Monoclonal IgG Productivity, Product Quality And Antigen-Binding Affinity
A signal peptide is a 5-30 amino acid (aa) peptide present at the N-terminus of secretory proteins.
How to Optimize Duolink® PLA for Flow Cytometry Detection
Considerations for proper experimental design, preparation and execution of the Duolink® PLA for flow cytometry protocol.
Duolink® PLA Troubleshooting Guide
Support information including tips and tricks, frequently asked questions, and basic troubleshooting.
3xFLAG® System Expression Vectors for Ultra-Sensitive Detection of Recombinant Proteins
The 3xFLAG system is an improvement upon the original system by fusing 3 tandem FLAG® epitopes for a total of 22 amino acids. Detection of fusion proteins containing 3xFLAG is enhanced up to 200 times more than any other system.
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