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显示 1-30 共 266 条结果 关于 "L3126" 范围 论文
Teresa del Castillo-Santaella et al.
Journal of agricultural and food chemistry, 63(47), 10333-10340 (2015-11-10)
Inhibition of lipase activity is one of the approaches to reduced fat intake with nutritional prevention promoting healthier diet. The food industry is very interested in the use of natural extracts, hence reducing the side effects of commercial drugs inhibiting
S Roudani et al.
Biochimica et biophysica acta, 1264(1), 141-150 (1995-10-17)
In human fetal pancreas, we identified two cDNA transcripts of the bile salt-dependent lipase (BSDL) using reverse transcription followed by polymerase chain reaction (RT-PCR). The sequence of four overlapping segments obtained by RT-PCR matched the sequence of the 2.2 kb
Teresa Herrera et al.
Food chemistry, 270, 509-517 (2018-09-04)
Ethanol extracts (EE) from fenugreek and quinoa seeds with different total content of inhibitory compounds (TIC, total saponin plus phenolic) were prepared with and without concentration of TIC (CEE -concentrated EE-, and EE, respectively). Their inhibitory activity on pancreatic lipase
Amit G Singal et al.
The American journal of gastroenterology, 109(3), 325-334 (2014-01-22)
The PNPLA3 rs738409 single-nucleotide polymorphism is known to promote nonalcoholic steatohepatitis (NASH), but its association with fibrosis severity and hepatocellular carcinoma (HCC) risk is less well-defined. The objectives of this study were to determine the association between PNPLA3 and liver
Mathios E Mylonakis et al.
Veterinary microbiology, 169(3-4), 198-202 (2014-02-18)
Ehrlichia canis infection causes multisystemic disease in dogs (canine monocytic ehrlichiosis, CME) which is associated with variable morbidity and mortality. Atypical clinical manifestations, including gastrointestinal signs, may occasionally occur in CME and approximately 10-15% of dogs are presented with historical
Joanne Pagnon et al.
Endocrinology, 153(9), 4278-4289 (2012-06-27)
Catecholamine-stimulated lipolysis occurs by activating adenylate cyclase and raising cAMP levels, thereby increasing protein kinase A (PKA) activity. This results in phosphorylation and modulated activity of several key lipolytic proteins. Adipose triglyceride lipase (ATGL) is the primary lipase for the
Mrinalini Muralidharan et al.
Plant molecular biology, 81(6), 565-576 (2013-02-23)
Acetylcholinesterase is an enzyme that is intimately associated with regulation of synaptic transmission in the cholinergic nervous system and in neuromuscular junctions of animals. However the presence of cholinesterase activity has been described also in non-metazoan organisms such as slime
Sang Hoon Lee et al.
Natural product communications, 8(10), 1439-1441 (2013-12-21)
Obesity, which is characterized by excessive fat accumulation, occurs by fat absorption by lipase and sequential fat accumulation in adipocytes through adipocyte differentiation. Thus, inhibition of pancreatic lipase activity and adipocyte differentiation would be crucial for the prevention and treatment
Jon Alberdi-Cedeño et al.
Antioxidants (Basel, Switzerland), 9(6) (2020-06-25)
The changes provoked by in vitro digestion in the lipids of olive oil enriched or not with different phenolic compounds were studied by proton nuclear magnetic resonance (1H NMR) and solid phase microextraction followed by gas chromatography/mass spectrometry (SPME-GC/MS). These
Sanghak Cha et al.
Scientific reports, 9(1), 6363-6363 (2019-04-26)
Although enzymes are efficient catalysts capable of converting various substrates into desired products with high specificity under mild conditions, their effectiveness as catalysts is substantially reduced when substrates are poorly water-soluble. In this study, to expedite the enzymatic conversion of
Veit Schoenborn et al.
Diabetes, 55(5), 1270-1275 (2006-04-29)
Adipose triglyceride lipase (ATGL) was recently described to predominantly perform the initial step in triglyceride hydrolysis and therefore seems to play a pivotal role in the lipolytic catabolism of stored fat in adipose tissue. In the first study investigating genetic
Yang Wei et al.
Food & function, 12(7), 3246-3265 (2021-04-21)
In this study, β-carotene loaded oil-in-water emulsions were stabilized by complex interfaces composed of propylene glycol alginate (PGA), rhamnolipids (Rha), and zein colloidal particles (ZCPs). The influence of mixed biopolymer-surfactant, biopolymer-particle, surfactant-particle and biopolymer-surfactant-particle interfaces on the performance of the
H van Tilbeurgh et al.
Nature, 359(6391), 159-162 (1992-09-10)
Interfacial adsorption of pancreatic lipase is strongly dependent on the physical chemical properties of the lipid surface. These properties are affected by amphiphiles such as phospholipids and bile salts. In the presence of such amphiphiles, lipase binding to the interface
Osvaldo Manuel Tiscornia et al.
Acta gastroenterologica Latinoamericana, 43(4), 294-300 (2014-02-13)
The present tests were undertaken in order to analyze in male Wistar rats the changes in the exocrine and endocrine pancreas and on the interactions that normally evolve in the insulo-pancreon-axis. To evaluate this by a single i.p. Boots secretin
Takanori Matsui et al.
Biochemical and biophysical research communications, 443(3), 847-851 (2013-12-18)
Pigment epithelium-derived factor (PEDF) has anti-inflammatory and anti-thrombogenic properties both in cell culture and animal models. Although adipose triglyceride lipase (ATGL) and laminin receptor (LR) are two putative receptors for PEDF, which receptor mainly mediates the beneficial effects of PEDF
Felipe Jiménez-Aspee et al.
Food research international (Ottawa, Ont.), 114, 90-96 (2018-10-27)
The Bromeliaceae Puya chilensis Mol. is a native monocotyledonous food plant that can be found in central Chile. It is traditionally known as chagual. The tender basal part of the leaves, just starting from the meristem, are consumed as a
Roman A Sidorov et al.
Chemistry & biodiversity, 13(6), 789-797 (2016-05-07)
The positional-species composition (PSC) of 3-acetyl-1,2-diacyl-sn-glycerols (AcDAGs) from the seeds of mature fruits of 14 species of the genus Euonymus L. was established. The residues of six major fatty acids (FAs), palmitic (P), stearic (St), hexadecenoic (H), octadecenoic (O), linoleic
Magali C Cammarota et al.
Environmental technology, 34(1-4), 417-428 (2013-03-28)
The effect of a lipase-rich enzyme preparation produced by the fungus Penicillium sp. on solid-state fermentation was evaluated in two anaerobic bioreactors (up-flow anaerobic sludge blanket (UASB) and horizontal-flow anaerobic immobilized biomass (HAIB)) treating dairy wastewater with 1200 mg oil
B M McArthur et al.
The British journal of nutrition, 123(4), 361-371 (2019-10-18)
The bioaccessibility of fat has implications for satiety and postprandial lipidaemia. The prevailing view holds that the integrity of plant cell wall structure is the primary determinant of energy and nutrient extraction from plant cells as they pass through the
Araceli E Rossignoli et al.
Toxicon : official journal of the International Society on Toxinology, 55(2-3), 221-226 (2009-08-04)
The subcellular distribution of okadaic acid, the main diarrhetic shellfish poisoning (DSP) toxin, in the cells of the digestive gland of the mussel Mytilus galloprovincialis was studied. By means of differential centrifugation, ultrafiltration and extraction with methanol, it was found
Helge Raeder et al.
Nature genetics, 38(1), 54-62 (2005-12-22)
Dysfunction of the exocrine pancreas is observed in diabetes, but links between concurrent exocrine and endocrine pancreatic disease and contributing genetic factors are poorly characterized. We studied two families with diabetes and exocrine pancreatic dysfunction by genetic, physiological and in
Jon Alberdi-Cedeño et al.
Antioxidants (Basel, Switzerland), 9(4) (2020-04-25)
The effect of enriching virgin flaxseed oil with dodecyl gallate, hydroxytyrosol acetate or gamma-tocopherol on its in vitro digestion is studied by means of proton nuclear magnetic resonance and solid phase microextraction followed by gas chromatography/mass spectrometry. The extent and
Stefano Romeo et al.
Nature genetics, 40(12), 1461-1465 (2008-09-30)
Nonalcoholic fatty liver disease (NAFLD) is a burgeoning health problem of unknown etiology that varies in prevalence among ancestry groups. To identify genetic variants contributing to differences in hepatic fat content, we carried out a genome-wide association scan of nonsynonymous
Stephen G Young et al.
Genes & development, 27(5), 459-484 (2013-03-12)
All organisms use fatty acids (FAs) for energy substrates and as precursors for membrane and signaling lipids. The most efficient way to transport and store FAs is in the form of triglycerides (TGs); however, TGs are not capable of traversing
Amelia Torcello-Gómez et al.
Food & function, 8(6), 2231-2242 (2017-06-14)
The development of emulsion-based products through optimisation of ingredients, reduction in energy-input during manufacture, while fulfilling healthy attributes, are major objectives within the food industry. Instant emulsions can meet these features, but comprehensive studies are necessary to investigate the effect
Daniella C Murador et al.
Food chemistry, 339, 127818-127818 (2020-08-28)
Native extracts from orange peels were obtained by a conventional method using acetone and, an alternative method using ionic liquid (1-butyl-3-methylimidazolium chloride ([C4mim]Cl)). The bioaccessibilities and cellular uptakes of carotenoids, esters and chlorophylls were evaluated, since the influence of esterification
M R Probst et al.
Biochemical and biophysical research communications, 177(1), 453-459 (1991-05-31)
Arylacetamide deacetylation is an important enzyme activity in the metabolic activation of arylamine substrates to ultimate carcinogens, best described as a carboxylesterase/amidase type of reaction. A 7-fold variation in the Vmax of 2-acetylaminofluorene deacetylation in 24 human livers was observed.
Tao Liu et al.
Journal of proteome research, 4(6), 2070-2080 (2005-12-13)
The enormous complexity, wide dynamic range of relative protein abundances of interest (over 10 orders of magnitude), and tremendous heterogeneity (due to post-translational modifications, such as glycosylation) of the human blood plasma proteome severely challenge the capabilities of existing analytical
Rui Chen et al.
Journal of proteome research, 8(2), 651-661 (2009-01-23)
The study of protein glycosylation has lagged far behind the progress of current proteomics because of the enormous complexity, wide dynamic range distribution and low stoichiometric modification of glycoprotein. Solid phase extraction of tryptic N-glycopeptides by hydrazide chemistry is becoming
Cristobal Verdugo et al.
Bioresource technology, 101(17), 6657-6662 (2010-04-10)
A comprehensive study of critical parameters in the pig pancreatic lipase (PPL) catalysed transesterification of sunflower oil to novel biofuels integrating glycerol into their composition is reported. The influence of oil/alcohol ratio, temperature, quantity of enzyme and water added and
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