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关键词:'M1750000'
显示 1-30 共 172 条结果 关于 "M1750000" 范围 论文
Aysha Z Akhtar et al.
Alternatives to laboratory animals : ATLA, 37(1), 43-62 (2009-03-19)
The objective of this study was to examine whether animal studies can reliably be used to determine the usefulness of methylprednisolone (MP) and other treatments for acute spinal cord injury (SCI) in humans. This was achieved by performing a systematic
Corticosteroids for severe community-acquired pneumonia: not for everyone.
Richard G Wunderink
JAMA, 313(7), 673-674 (2015-02-18)
Jia Li et al.
Experimental biology and medicine (Maywood, N.J.), 240(2), 273-280 (2014-10-09)
In this study, we examined whether local deferoxamine (DFO) administration can promote angiogenesis and bone repair in steroid-induced osteonecrosis of the femoral head (ONFH). Steroid-induced ONFH was induced in 65 mature male New Zealand white rabbits by methylprednisolone in combination
Julia A E Walters et al.
The Cochrane database of systematic reviews, 12(12), CD006897-CD006897 (2014-12-11)
Current guidelines recommend that patients with acute exacerbations of chronic obstructive pulmonary disease (COPD) should be treated with systemic corticosteroid for seven to 14 days. Intermittent systemic corticosteroid use is cumulatively associated with adverse effects such as osteoporosis, hyperglycaemia and
A novel tri-allelic mutation of TMPRSS6 in iron-refractory iron deficiency anaemia with response to glucocorticoid.
Neng Nie et al.
British journal of haematology, 166(2), 300-303 (2014-03-26)
Susan Byrne et al.
Developmental medicine and child neurology, 56(8), 794-796 (2014-03-20)
N-methyl-d-aspartate (NMDA) receptor encephalitis is a treatable cause of autoimmune encephalitis in both children and adults. It is still unclear if the natural history of the condition in children is altered by early treatment with immunosuppressive therapy. We looked at
Reversible pure word deafness.
Ashok Verma et al.
JAMA neurology, 70(11), 1454-1455 (2013-10-02)
Fungal meningitis outbreak affects over 700.
Carrie Arnold
The Lancet. Neurology, 12(5), 429-430 (2013-04-23)
Silje Agnethe Stokke Kvistad et al.
Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 133(19), 2057-2061 (2013-10-17)
Neuromyelitis optica (NMO) is a rare autoimmune inflammatory disease of the central nervous system that is characterized mainly by recurrent optic neuritis and longitudinally extensive transverse myelitis. The aim of this article is to present current knowledge on the clinical
Colin E Thomson et al.
The Journal of bone and joint surgery. American volume, 95(9), 790-798 (2013-05-03)
Morton neuroma is a common cause of neuralgia affecting the web spaces of the toes. Corticosteroid injections are commonly administered as a first-line therapy, but the evidence for their effectiveness is weak. Our primary research aim was to determine whether
Krzysztof Marycz et al.
Acta veterinaria Hungarica, 62(3), 317-333 (2014-03-25)
Disorders of the locomotive system, especially those occurring due to degenerative changes of the joints, are serious problems in daily veterinary medical practice. Steroid injections are the main way of treating these disorders. However, this approach brings usually only temporary
Tyree H Kiser et al.
American journal of respiratory and critical care medicine, 189(9), 1052-1064 (2014-03-13)
Studies evaluating corticosteroid (CS) dosing for patients hospitalized with an acute exacerbation of chronic obstructive pulmonary disease (AECOPD) have largely excluded patients admitted directly to the intensive care unit (ICU), and none have evaluated the effect of CS dosing regimens
Simon W J Grant et al.
Dental update, 40(8), 669-670 (2013-11-28)
Giant cell arteritis (GCA) is a systemic vasculitis with symptoms that could cause a patient to present to a general dental practitioner. A case of GCA that presented as headache, jaw claudication, unilateral visual loss and tongue ulceration leading to
Zoltán Liptai et al.
Ideggyogyaszati szemle, 66(1-2), 67-71 (2013-04-24)
Authors, most of them Japanese, have recently published an increasing number of articles on mild encephalitis/encephalopathy with a reversible splenial lesion. We report on two new white European patients and compare published data with our own observations. A 15-year-old girl
Jingwu Liao et al.
Molecular medicine reports, 10(3), 1225-1230 (2014-06-28)
Elevation of intracellular cyclic adenosine monophosphate (cAMP) levels facilitates recovery following spinal injury by suppressing secondary pathology and promoting axonal regeneration. However, this treatment strategy is limited by lack of effective and tolerable clinical agents. The present study examined the
Marie B Condon et al.
Annals of the rheumatic diseases, 72(8), 1280-1286 (2013-06-07)
Lupus nephritis (LN) is a serious complication of systemic lupus erythematosus (SLE). All current treatment regimens include oral steroids, which are associated with severe adverse events and long-term damage. We have piloted a steroid-avoiding protocol (rituxilup) for the treatment of
Eliska Bílková et al.
Current pharmaceutical design, 17(32), 3577-3595 (2011-11-15)
Glucocorticoid drugs are commonly used in the treatment of many acute and chronic inflammatory diseases. However, application of these steroids is limited because of their physico-chemical properties, such as very low water solubility. Glucocorticoids also exhibit serious adverse side effects.
Zhihong Liu et al.
Annals of internal medicine, 162(1), 18-26 (2014-11-11)
Treatment of lupus nephritis (LN) remains challenging. To assess the efficacy and safety of a multitarget therapy consisting of tacrolimus, mycophenolate mofetil, and steroid compared with intravenous cyclophosphamide and steroid as induction therapy for LN. 24-week randomized, open-label, multicenter study.
Richard W Browne et al.
Journal of neurology, neurosurgery, and psychiatry, 85(8), 859-864 (2014-01-29)
There is increasing evidence that serum lipoprotein cholesterol biomarkers are associated with disease progression in clinically isolated syndromes (CIS). Apolipoproteins (Apo) are recognition ligands that mediate the physiological interactions of cholesterol-containing lipoproteins. The objective of this study was to investigate
A case of opsoclonus-myoclonus syndrome following a septic shock.
A Daumas et al.
Anaesthesia and intensive care, 41(6), 810-811 (2013-11-05)
Yoshikatsu Hosoda et al.
American journal of ophthalmology, 157(5), 1056-1063 (2014-02-05)
To investigate the correlation between choroidal and retinal lesions in eyes with acute Vogt-Koyanagi-Harada disease (VKH) using optical coherence tomography (OCT) by using a new parameter, retinal pigment epithelium (RPE) undulation index, which quantitatively describes choroidal deformations. Retrospective, observational, cross-sectional
Guillermo Ruiz-Irastorza et al.
Autoimmunity reviews, 13(2), 206-214 (2013-11-06)
To assess the effectiveness and safety of a protocol using medium doses of prednisone to treat lupus nephritis. Patients receiving the 'Cruces-protocol cohort' (CPC) were paired 1:2 with patients from the 'historic cohort' (HC). The CPC received medium doses of
Combination regimen of leflunomide plus methylprednisolone in a female patient with reactive arthritis and concomitant IgA nephropathy.
Yi-zhi Chen et al.
Chinese medical journal, 123(3), 375-378 (2010-03-03)
[CME. Severe cutaneous drug reaction].
Jeremy Deuel et al.
Praxis, 103(21), 1231-1243 (2014-10-12)
MMWR. Morbidity and mortality weekly report, 62(19), 377-381 (2013-05-17)
As of May 6, 2013, Michigan had reported 167 (52%) of the 320 paraspinal or spinal infections without meningitis associated with the 2012-2013 fungal meningitis outbreak nationally. Although the index patient had a laboratory-confirmed Aspergillus fumigatus infection, the fungus most
Xuejia Zhai et al.
Journal of pharmaceutical and biomedical analysis, 107, 450-455 (2015-02-11)
Chronic stress as well as major depressive disorders is associated with cortisol metabolism. Two enzymes modulate cortisol (F) and cortisone (E) interconversion: 11β-hydroxysteroid dehydrogenase type 1 and type 2 (11β-HSD1 and 11β-HSD2). Furthermore, F and E were inactivated by 5α
N-methyl-D-aspartate receptor antibody encephalitis: how much treatment is enough?
Susan Byrne et al.
Developmental medicine and child neurology, 57(1), 14-15 (2014-08-12)
Zhengming Gu et al.
Archives of pathology & laboratory medicine, 138(11), 1474-1480 (2014-10-31)
Invasive fungal infections are an important cause of morbidity and mortality among immunocompromised patients. To design and evaluate a multiplexed assay aimed at quantitative detection and differentiation of the 5 molds that are most commonly responsible for pulmonary infections. Using
Ricardo Vieira Botelho et al.
Revista da Associacao Medica Brasileira (1992), 55(6), 729-737 (2010-03-02)
Steroid therapy has been tested as a protector in spinal cord injury. Multicenter studies evaluating the methylprednisolone (MP) in post traumatic neurological recovery have shown promising results according to NASCIS. A large number of critical studies related to the NASCIS
In Hwan Cho et al.
Journal of glaucoma, 24(1), 81-83 (2013-02-23)
To report a case of bilateral simultaneous angle-closure glaucoma caused by septic condition of Korean hemorrhagic fever. A 62-year-old man visited our emergency center with signs of sepsis (fever, leukocytosis, and oliguria). After 4 days of hospitalization, the patient reported
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