CN
Search Within
M1850000
应用筛选条件
关键词:'M1850000'
显示 1-30 共 95 条结果 关于 "M1850000" 范围 论文
Anjan Debnath et al.
Antimicrobial agents and chemotherapy, 58(7), 4138-4144 (2014-05-14)
Entamoeba histolytica and Giardia lamblia are anaerobic protozoan parasites that cause amebiasis and giardiasis, two of the most common diarrheal diseases worldwide. Current therapy relies on metronidazole, but resistance has been reported and the drug has significant adverse effects. Therefore
Qian Li et al.
Microbes and infection, 16(1), 17-27 (2013-10-22)
Pseudomonas aeruginosa is an important opportunistic bacterial pathogen, causing infections of respiratory and other organ systems in immunocompromised hosts that may invade and proliferate in mucosal epithelial cells to induce apoptosis. Previous studies suggest that oral bacteria, especially gram-negative periodontal
Daehee Han et al.
PloS one, 10(2), e0118795-e0118795 (2015-02-18)
We have previously generated a mouse model of spontaneous Th2-associated disease of the small intestine called TRAF6ΔDC, in which dendritic cell (DC)-intrinsic expression of the signaling mediator TRAF6 is ablated. Interestingly, broad-spectrum antibiotic treatment ameliorates TRAF6ΔDC disease, implying a role
Mamun-Ur Rashid et al.
Anaerobe, 28, 216-219 (2014-07-13)
One hundred fourteen Clostridium difficile strains were collected from 67 patients and analyzed for the presence of C. difficile toxin B by the cell cytotoxoicity neutralization assay, genes for toxin A, toxin B, binary toxin and TcdC deletion by PCR. All
Lee-Wei Chen et al.
Journal of the American College of Surgeons, 219(4), 606-619 (2014-09-23)
Burn patients can incur high rates of hospital-acquired infections. The mechanism of antibiotic exposure on inducing infection vulnerability has not been determined. This study aimed to examine the effects of antibiotic treatment on host defense mechanisms. First we treated C57/BL6
Jiajia Xue et al.
Biomaterials, 35(34), 9395-9405 (2014-08-20)
Infection is the major reason for guided tissue regeneration/guided bone regeneration (GTR/GBR) membrane failure in clinical application. In this work, we developed GTR/GBR membranes with localized drug delivery function to prevent infection by electrospinning of poly(ε-caprolactone) (PCL) and gelatin blended
Wendy Itzel Escobedo Hinojosa et al.
Journal of ethnopharmacology, 155(2), 1156-1163 (2014-06-28)
The root barks of Hippocratea celastroides have been used for decades in Mexican traditional medicine to treat gastritis and ulcers. To investigate the anti-Helicobacter pylori, gastroprotective, anti-inflammatory, and cytotoxic activities of methanolic extracts obtained from the leaves, stems, and root
Shankumar Mooyottu et al.
International journal of food microbiology, 192, 111-116 (2014-12-03)
Clostridium difficile is a pathogen of significant public health concern causing a life-threatening, toxin-mediated enteric disease in humans. The incidence and severity of the disease associated with C. difficile have increased in the US with the emergence of hypervirulent strains
Catherine M Zip
Dermatologic clinics, 28(3), 525-534 (2010-06-01)
Metronidazole is a synthetic nitroimidazole derivative with antimicrobial and antiinflammatory properties. It was the first topical therapy approved solely for rosacea and remains a cornerstone of rosacea management. This article reviews the optimal use of topical metronidazole in the treatment
Kristine A Kuhn et al.
PloS one, 9(12), e114195-e114195 (2014-12-06)
IL-6 is a pleiotropic cytokine often associated with inflammation. Inhibition of this pathway has led to successful treatment of rheumatoid arthritis, but one unforeseen potential complication of anti-IL-6 therapy is bowel perforation. Within the intestine, IL-6 has been shown to
M Catherine McEllistrem et al.
Southern medical journal, 107(9), 597-599 (2014-09-05)
The 2010 Infectious Diseases Society of America/Society for Healthcare Epidemiology of America treatment guidelines for Clostridium difficile infections (CDI) recommend oral metronidazole for mild-to-moderate disease and oral vancomycin for severe disease. Given that disease severity is easily determined by the
Yasuhiro Horita et al.
Antimicrobial agents and chemotherapy, 58(6), 3168-3176 (2014-03-26)
Predicting drug-drug interactions (DDIs) related to cytochrome P450 (CYP), such as CYP3A4 and one of the major drug transporters, P-glycoprotein (P-gp), is crucial in the development of future chemotherapeutic regimens to treat tuberculosis (TB) and TB/AIDS coinfection cases. We evaluated
Dina Zandbergen et al.
Journal of periodontology, 84(3), 332-351 (2012-05-23)
The treatment of periodontitis frequently begins with a non-surgical phase that includes scaling and root planing (SRP) and, on occasion, the use of systemic antibiotics. The goal of this review is to systematically evaluate the data concerning the effect of
Michael Selgrad et al.
World journal of gastroenterology, 20(43), 16245-16251 (2014-12-05)
To assess whether antibiotic resistance varies between the antrum and corpus of the stomach of patients that are either Helicobacter pylori (H. pylori) therapy-naive or pre-treated. H. pylori strains were isolated from antrum and corpus biopsies from 66 patients that
Michael D Huband et al.
Antimicrobial agents and chemotherapy, 59(1), 467-474 (2014-11-12)
AZD0914 is a new spiropyrimidinetrione bacterial DNA gyrase/topoisomerase inhibitor with potent in vitro antibacterial activity against key Gram-positive (Staphylococcus aureus, Staphylococcus epidermidis, Streptococcus pneumoniae, Streptococcus pyogenes, and Streptococcus agalactiae), fastidious Gram-negative (Haemophilus influenzae and Neisseria gonorrhoeae), atypical (Legionella pneumophila), and
Clostridium difficile in retail baskets, trolleys, conveyor belts, and plastic bags in Saudi Arabia.
Mohammed A Alqumber
Saudi medical journal, 35(10), 1274-1277 (2014-10-16)
To determine Clostridium difficile (C. difficile) prevalence on retail surfaces and shoppers plastic bags. From 20 June to 10 August 2011, in a cross-sectional epidemiological study, 17 supermarkets from 2 cities, Albaha and Altaif, Saudi Arabia were sampled. A total
Vancomycin-associated neutrophilic dermatitis histologically mimicking Cryptococcus.
Alan S Boyd et al.
Journal of the American Academy of Dermatology, 70(4), e86-e88 (2014-03-19)
Andrey Galkin et al.
The Journal of biological chemistry, 289(15), 10502-10509 (2014-02-22)
Carbamate kinase from Giardia lamblia is an essential enzyme for the survival of the organism. The enzyme catalyzes the final step in the arginine dihydrolase pathway converting ADP and carbamoyl phosphate to ATP and carbamate. We previously reported that disulfiram
Marin J de Jong et al.
Archives of disease in childhood, 99(12), 1109-1113 (2014-07-24)
The association between Dientamoeba (D.) fragilis and the aetiology of functional gastrointestinal disorders (FGID) in children is unclear. The aim of this retrospective case-control study is to clarify the clinical relevance of D. fragilis in children with chronic abdominal pain.
Fang-Hsuean Liao et al.
Cell & bioscience, 4, 25-25 (2014-06-07)
Protein phosphates 4 (PP4), encoded by the ppp4c gene, is a ubiquitously expressed phosphatase that has been implicated in the regulation of cytokine signaling and lymphocyte survival; recent reports suggest that PP4 may be involved in pre-TCR signaling and B
Horacio Reyes-Vivas et al.
Antimicrobial agents and chemotherapy, 58(12), 7072-7082 (2014-09-17)
Giardiasis is highly prevalent in the developing world, and treatment failures with the standard drugs are common. This work deals with the proposal of omeprazole as a novel antigiardial drug, focusing on a giardial glycolytic enzyme used to follow the
Priscileila Colerato Ferrari et al.
Drug development and industrial pharmacy, 40(8), 1123-1131 (2013-07-03)
Alternating Current Biosusceptometry is a magnetically method used to characterize drug delivery systems. This work presents a system composed by an automated ACB sensor to acquire magnetic images of floating tablets. The purpose of this study was to use an
Claudia M Hemsley et al.
Antimicrobial agents and chemotherapy, 58(10), 5775-5783 (2014-07-23)
Noninherited antibiotic resistance is a phenomenon whereby a subpopulation of genetically identical bacteria displays phenotypic tolerance to antibiotics. We show here that compared to Escherichia coli, the clinically relevant genus Burkholderia displays much higher levels of cells that tolerate ceftazidime.
Ebola in Freetown area, Sierra Leone--a case study of 581 patients.
Rashid Ansumana et al.
The New England journal of medicine, 372(6), 587-588 (2014-12-30)
Ying-Ting Huang et al.
Acta neurologica Taiwanica, 21(2), 74-78 (2012-08-11)
Neurotoxicities resulting from various medications are under diagnosed; Metronidazole-induced encephalopathy is one of them. Here we present two patients with a history of metronidazole use and discuss neuroimaging findings. We report two patients suffering from acute neurological symptoms associated with
K A Knoop et al.
Mucosal immunology, 8(1), 198-210 (2014-07-10)
The delivery of luminal substances across the intestinal epithelium to the immune system is a critical event in immune surveillance, resulting in tolerance to dietary antigens and immunity to pathogens. How this process is regulated is largely unknown. Recently goblet
C Rodriguez et al.
Veterinary microbiology, 172(1-2), 309-317 (2014-06-05)
Clostridium difficile has been identified as a significant agent of diarrhoea and enterocolitis in both foals and adult horses. Hospitalization, antibiotic therapy or changes in diet may contribute to the development of C. difficile infection. Horses admitted to a care
Norberto C Chavez-Tapia et al.
The Cochrane database of systematic reviews, (1)(1), CD004886-CD004886 (2009-01-23)
Metronidazole is the standard of care for uncomplicated amoebic liver abscesses (considering that complicated liver abscesses are those localized in left lobe, multiple, and/or pyogenic abscesses). However, a subset of patients with amoebic liver abscesses remain symptomatic, with a significant
Holly M Pope et al.
PloS one, 9(7), e103283-e103283 (2014-07-25)
Axon degeneration is a feature of many peripheral neuropathies. Understanding the organismal response to this degeneration may aid in identifying new therapeutic targets for treatment. Using a transgenic zebrafish line expressing a bacterial nitroreductase (Ntr)/mCherry fusion protein in the peripheral
Metronidazole-induced encephalopathy: a case report and review of the literature.
Michelle M Bottenberg et al.
Journal of clinical pharmacology, 51(1), 112-116 (2010-03-12)
1/4