CN
Search Within
m4880
应用筛选条件
关键词:'m4880'
显示 1-30 共 3888 条结果 关于 "m4880" 范围 论文
Anna Löschberger et al.
Journal of cell science, 127(Pt 20), 4351-4355 (2014-08-26)
Here, we combine super-resolution fluorescence localization microscopy with scanning electron microscopy to map the position of proteins of nuclear pore complexes in isolated Xenopus laevis oocyte nuclear envelopes with molecular resolution in both imaging modes. We use the periodic molecular
Juan Alejandro Perdomo et al.
Photosynthesis research, 124(1), 67-75 (2015-02-11)
There is general consensus in the literature that plants with different photosynthetic mechanisms (i.e. C3 vs. C4) have Rubiscos characterised by different kinetic performances. However, potential differences in the temperature dependencies of Rubisco kinetic parameters between C3 and C4 plants
Susan Schuster et al.
Journal of virology, 88(22), 13447-13459 (2014-09-12)
Insects are a reservoir for many known and novel viruses. We discovered an unknown virus, tentatively named mosinovirus (MoNV), in mosquitoes from a tropical rainforest region in Côte d'Ivoire. The MoNV genome consists of two segments of positive-sense RNA of
Knut Kirmse et al.
Nature communications, 6, 7750-7750 (2015-07-17)
A large body of evidence from in vitro studies suggests that GABA is depolarizing during early postnatal development. However, the mode of GABA action in the intact developing brain is unknown. Here we examine the in vivo effects of GABA
Mohammed Basahi
Comptes rendus biologies, 338(11), 723-727 (2015-10-27)
Inter simple sequence repeats (ISSR) analysis was used to determine the genetic diversity among 15 genotypes of sorghum [Sorghum bicolor (L.) Moench] growing in some parts of Saudi Arabia and Yemen. A total of 92 alleles were amplified, with an
Bo Cao et al.
International journal of molecular medicine, 35(3), 771-776 (2015-01-17)
The need to overcome cancer multidrug resistance (MDR) has fueled considerable interest in the development of novel synthetic antitumor agents with cytotoxicity against cancer cell lines with MDR. In this study, we aimed to investigate CIP-36, a novel podophyllotoxin derivative
Clarissa Muere et al.
Journal of applied physiology (Bethesda, Md. : 1985), 119(3), 308-320 (2015-05-30)
Previous work in intact awake and sleeping goats has found that unilateral blockade of excitatory inputs in the ventral respiratory column (VRC) elicits changes in the concentrations of multiple neurochemicals, including serotonin (5-HT), substance P, glycine, and GABA, while increasing
Yanru Zeng et al.
BMC genetics, 15 Suppl 1, S2-S2 (2014-08-01)
Torreya grandis Fort. ex Lindl, a conifer species widely distributed in Southeastern China, is of high economic value by producing edible, nutrient seeds. However, knowledge about the genome structure and organization of this species is poorly understood, thereby limiting the
Qin Wang et al.
Neurochemical research, 40(5), 924-931 (2015-03-03)
Taurine is a sulfur-containing amino acid present in high concentrations in mammalian tissues, and has been implicated in several processes involving brain development and neurotransmission. However, the role of taurine in inner ear neural development is still largely unknown. Here
Damon Polioudakis et al.
PloS one, 10(5), e0126535-e0126535 (2015-05-21)
miRNAs play a central role in numerous pathologies including multiple cancer types. miR-191 has predominantly been studied as an oncogene, but the role of miR-191 in the proliferation of primary cells is not well characterized, and the miR-191 targetome has
Armêl Millet et al.
Scientific reports, 5, 13154-13154 (2015-08-25)
The enzymatic DNA relaxation requires the DNA to be transiently nicked and rejoined, the covalent topoisomerase-DNA complex being a key intermediate of the nicking-joining reaction. Practically, this reaction is most often characterized by oligonucleotides. However, the incision-religation of an oligonucleotide
S Schuster et al.
Molecular psychiatry, 20(9), 1120-1131 (2015-04-15)
Neuropsychiatric developmental disorders, such as autism spectrum disorders (ASDs) and schizophrenia, are typically characterized by alterations in social behavior and have been linked to aberrant dendritic spine and synapse development. Here we show, using genetically engineered mice, that the Cdc42
Irina Anosova et al.
Nucleic acids research, 43(10), 5208-5220 (2015-04-29)
The chromatin remodeling complex NoRC, comprising the subunits SNF2h and TIP5/BAZ2A, mediates heterochromatin formation at major clusters of repetitive elements, including rRNA genes, centromeres and telomeres. Association with chromatin requires the interaction of the TAM (TIP5/ARBP/MBD) domain of TIP5 with
Han-Peng Jiang et al.
The Analyst, 139(19), 4940-4946 (2014-07-30)
In the current study, we developed a facile strategy for the one-pot synthesis of an aptamer-based organic-silica hybrid monolithic capillary column. A 5'-SH-modified aptamer, specifically targeting doxorubicin, was covalently modified in the hybrid silica monolithic column by a sol-gel method
Thierry K Ngouana et al.
Mycoses, 58(1), 33-39 (2014-10-08)
Minor species of the Candida albicans complex may cause overestimation of the epidemiology of C. albicans, and misidentifications could mask their implication in human pathology. Authors determined the occurrence of minor species of the C. albicans complex (C. africana, C.
José Luís Dores-Sousa et al.
Toxicology, 329, 106-119 (2015-01-15)
Age is a known susceptibility factor for the cardiotoxicity of several anticancer drugs, including mitoxantrone (MTX). The impact of anticancer drugs in young patients is underestimated, thus we aimed to evaluate the cardiotoxicity of MTX in juvenile and adult animals.
Nuclear translocation of p19INK4d in response to oxidative DNA damage promotes chromatin relaxation.
Silvina V Sonzogni et al.
Molecular and cellular biochemistry, 398(1-2), 63-72 (2014-09-11)
DNA is continuously exposed to damaging agents that can lead to changes in the genetic information with adverse consequences. Nonetheless, eukaryotic cells have mechanisms such as the DNA damage response (DDR) to prevent genomic instability. The DNA of eukaryotic cells
Xiao-Yun Yang et al.
Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 36(11), 2027-2033 (2015-07-15)
Lysophosphatidic acid (LPA) is a bioactive phospholipid that activates at least five known G-protein-coupled receptors (GPCRs): LPA1-LPA5. The nervous system is a major locus for LPA1 expression. LPA has been shown to regulate neuronal proliferation, migration, and differentiation during central
Steven Lacy et al.
Drug metabolism and disposition: the biological fate of chemicals, 43(8), 1190-1207 (2015-05-28)
Metabolism and excretion of cabozantinib, an oral inhibitor of receptor tyrosine kinases, was studied in 8 healthy male volunteers after a single oral dose of 175 mg cabozantinib l-malate containing (14)C-cabozantinib (100 µCi/subject). Total mean radioactivity recovery within 48 days
Jung Min Hwang et al.
Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology, 126(7), 1348-1353 (2014-12-03)
To investigate whether there is a relation between the plasticity induced by different intensities of facilitatory rTMS with different intensities and brain-derived neurotrophic factor (BDNF) genotype. Forty healthy volunteers (14 men, mean age 27.3years) were enrolled. All participants received three
R Jason Pitts et al.
PloS one, 9(10), e111858-e111858 (2014-11-02)
The principal Afrotropical malaria vector mosquito, Anopheles gambiae remains a significant threat to human health. In this anthropophagic species, females detect and respond to a range of human-derived volatile kairomones such as ammonia, lactic acid, and other carboxylic acids in
Anne-Sophie Bergot et al.
PLoS pathogens, 10(10), e1004466-e1004466 (2014-10-24)
Human Papillomavirus (HPV) 16 E7 protein promotes the transformation of HPV infected epithelium to malignancy. Here, we use a murine model in which the E7 protein of HPV16 is expressed as a transgene in epithelium to show that mast cells
Jose M Sánchez-Robles et al.
Molecular ecology, 23(24), 6165-6178 (2014-10-31)
Plant architecture is crucial to pollination and mating in wind-pollinated species. We investigated the effect of crown architecture on pollen dispersal, mating system and offspring quality, combining phenotypic and genotypic analyses in a low-density population of the endangered species Abies
Shoaib Ashraf et al.
International journal for parasitology, 45(9-10), 647-654 (2015-05-10)
Haemonchus contortus is a nematode of livestock that can cause severe disease and mortality. Ivermectin, an anti-parasitic drug that targets glutamate-gated chloride channels, is widely used in humans, livestock, companion animals and agriculture. Although an association between genetic changes to
C Escobedo-Fregoso et al.
Transboundary and emerging diseases, 62(2), 137-147 (2013-04-24)
Prevalence of the protozoan Perkinsus spp. in the gills of the pleasure oyster Crassostrea corteziensis from two estuaries in Nayarit, Mexico, was measured. The protozoan was identified by PCR amplification of the internal transcribed spacer (ITS) region of the rDNA
Thomas Z Persson Vinnersten et al.
Insect science, 22(4), 549-559 (2014-06-05)
Floodwater mosquitoes (Diptera: Culicidae) are associated with periodically flooded wet meadows, marshes, and swamps in floodplains of major rivers worldwide, and their larvae are abundant in the shallow parts of flooded areas. The nuisance caused by the blood-seeking adult female
Yakov Y Woldman et al.
Biochemical and biophysical research communications, 465(2), 232-238 (2015-08-09)
A chemiluminescent method is proposed for quantitation of NO generation in cell cultures. The method is based on activation of soluble guanylyl cyclase by NO. The product of the guanylyl cyclase reaction, pyrophosphate, is converted to ATP by ATP sulfurylase
Gabsik Yang et al.
Journal of medicinal food, 18(9), 1013-1021 (2015-06-24)
Solanum tuberosum L. cv Jayoung (JY) is a potato with dark purple flesh and contains substantial amounts of polyphenols. In this study, we evaluated the therapeutic effects of S. tuberosum L. cv JY in a mouse model of Dermatophagoides farinae
Chun-Chi Wu et al.
PloS one, 10(7), e0132052-e0132052 (2015-07-07)
Koelreuteria henryi Dummer, an endemic plant of Taiwan, has been used as a folk medicine for the treatment of hepatitis, enteritis, cough, pharyngitis, allergy, hypertension, hyperlipidemia, and cancer. Austrobailignan-1, a natural lignan derivative isolated from Koelreuteria henryi Dummer, has anti-oxidative
Andrew Bell et al.
Plant molecular biology, 89(6), 539-558 (2015-09-09)
Among a set of genes in pea (Pisum sativum L.) that were induced under drought-stress growth conditions, one encoded a protein with significant similarity to a regulator of chlorophyll catabolism, SGR. This gene, SGRL, is distinct from SGR in genomic
1/130