CN
Search Within
P5295
应用筛选条件
关键词:'P5295'
显示 1-30 共 85 条结果 关于 "P5295" 范围 论文
J Gallinat et al.
Anasthesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS, 34(9), 520-527 (1999-10-30)
Delirium is a serious postoperative complication after general anaesthesia. The incidence is estimated to be about 10-15%. In the case of additional risk factors, such as old age, previously existing cerebral-vasculous and psychic deficiencies, and anaesthesia of long duration the
Piracetam and vinpocetine ameliorate rotenone-induced Parkinsonism in rats
Zaitone SA, et al.
International Journal of Pharmaceutics, 44(6), 774-774 (2012)
G Justus Hofmeyr et al.
The Cochrane database of systematic reviews, 6(6), CD001064-CD001064 (2012-06-15)
Piracetam is thought to promote the metabolism of brain cells when they are hypoxic. It has been used to prevent adverse effects of fetal distress. The objective of this review was to assess the effects of piracetam for suspected fetal
Kenji Inaba et al.
The journal of trauma and acute care surgery, 74(3), 766-771 (2013-02-22)
Brain Trauma Foundation guidelines recommend seizure prophylaxis for preventing early posttraumatic seizure (PTS). Phenytoin (PHE) is commonly used. Despite a paucity of data in traumatic brain injury, levetiracetam (LEV) has been introduced as a potential replacement, which is more costly
Przemyslaw M Mrozikiewicz et al.
Acta pharmaceutica (Zagreb, Croatia), 64(2), 223-232 (2014-06-11)
There are a number of compounds that can modify the activity of ABC (ATP-binding cassette) and SLC (solute carrier) transporters in the blood-brain barrier (BBB). The aim of this study was to investigate the effect of natural and synthetic substances
Ahmed H Ahmed et al.
Journal of medicinal chemistry, 53(5), 2197-2203 (2010-02-19)
Glutamate receptors are the most prevalent excitatory neurotransmitter receptors in the vertebrate central nervous system and are important potential drug targets for cognitive enhancement and the treatment of schizophrenia. Allosteric modulators of AMPA receptors promote dimerization by binding to a
Levetiracetam: a possible new inducer of toxic epidermal necrolysis and Stevens-Johnson syndrome in 2 cases.
Tu Anh Duong et al.
JAMA dermatology, 149(1), 113-115 (2013-01-18)
K Tajima et al.
Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 116(4), 209-214 (2000-11-21)
Myoclonus is defined as shock-like, brief involuntary abnormal movements in muscle jerking caused by external stimuli; and it arises from progressive myoclonus epilepsy, post-anoxic encephalopathy and Alzheimer's disease, causing disabling symptoms. It is a rare syndrome but very difficult to
Elisabetta Martini et al.
Journal of medicinal chemistry, 54(7), 2512-2516 (2011-03-09)
A series of cis and trans 3,7-diazabicyclo[4.3.0]nonan-8-ones has been synthesized and tested for their ability to revert scopolamine-induced amnesia in the mouse passive-avoidance test. The racemates of the most potent compounds 4 and 7 were separated and tested, but no
Bong Su Kang et al.
Epileptic disorders : international epilepsy journal with videotape, 15(3), 302-310 (2013-08-29)
To evaluate the long-term efficacy and safety of levetiracetam based on a large population of patients in a tertiary epilepsy centre. All patients who received levetiracetam at the Seoul National University Hospital between January 2007 and March 2009 were evaluated.
M M Asadullaev et al.
Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 112(10), 24-27 (2012-12-20)
Sixty patients were randomized to treatment with cytoflavin (n=30) or nootropil (n=30). Patients of the main group received cytoflavin along with standard treatment for correction of hemodynamics. The treatment scheme was as follows: intravenous injections during 10 days, tablets -
Levetiracetam-associated acute pancreatitis in an adolescent with autism: a case report.
Daniel M Almeida et al.
Pancreas, 42(1), 177-178 (2012-12-21)
Fulvio Gualtieri et al.
Current pharmaceutical design, 8(2), 125-138 (2002-01-29)
Cognition enhancers are drugs able to facilitate attentional abilities and acquisition, storage and retrieval of information, and to attenuate the impairment of cognitive functions associated with head traumas, stroke, age and age-related pathologies. Development of cognition enhancers is still a
Qingtao Gao et al.
Neurochemical research, 40(7), 1438-1447 (2015-05-23)
In our previous study, we demonstrated that nodakenin, a coumarin compound isolated from Angelica decursiva, ameliorates learning and memory impairments induced by scopolamine. In the present study, we investigated the effects of nodakenin on the cognitive function in the normal
Hélène Amieva et al.
PloS one, 8(1), e52755-e52755 (2013-01-18)
Numerous studies have looked at the potential benefits of various nootropic drugs such as Ginkgo biloba extract (EGb761®; Tanakan®) and piracetam (Nootropyl®) on age-related cognitive decline often leading to inconclusive results due to small sample sizes or insufficient follow-up duration.
Andrei G Malykh et al.
Drugs, 70(3), 287-312 (2010-02-20)
There is an increasing interest in nootropic drugs for the treatment of CNS disorders. Since the last meta-analysis of the clinical efficacy of piracetam, more information has accumulated. The primary objective of this systematic survey is to evaluate the clinical
S Ricci et al.
The Cochrane database of systematic reviews, (2)(2), CD000419-CD000419 (2006-04-21)
Piracetam has neuroprotective and antithrombotic effects which may help to reduce death and disability in people with acute stroke. The objective of this review was to assess the effects of piracetam in acute presumed ischaemic stroke. We searched the Cochrane
Phenytoin or levetiracetam for seizure prophylaxis in TBI.
Larissa DeDea
JAAPA : official journal of the American Academy of Physician Assistants, 25(12), 11-11 (2013-04-23)
Partha Palit et al.
Journal of ethnopharmacology, 159, 274-284 (2014-12-03)
Gelsemium sempervirens (L.) J.St.-Hil is a herb used for the treatment of various neuroses in both homeopathic and Ayurvedic systems. The present study examines whether Gelsemium reconstituted tincture can protect against scopolamine induced cognitive discrepancies in amnesic mouse model. In
Nitin K Sethi et al.
Drug metabolism and drug interactions, 28(2), 123-124 (2013-02-20)
Levetiracetam is a commonly used broad-spectrum anticonvulsant efficacious in both partial and generalized seizures. It has an extremely favorable side effect profile with few drug-drug interactions, low potential for hematological and hepatic toxicity, and thus has rapidly become the preferred
Marta Maschio et al.
Epileptic disorders : international epilepsy journal with videotape, 14(4), 388-397 (2012-12-19)
An open pilot study to evaluate the effect of pregabalin (PGB) as add-on therapy on seizure control, quality of life, and anxiety in patients with brain tumour-related epilepsy (BTRE). We recruited 25 consecutive patients with BTRE and uncontrolled seizures. At
[Current possibilities of the correction of oxidative stress in acute brain ischaemia].
E I Chukanova et al.
Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 112(11), 79-82 (2013-02-05)
A A Al Hajeri et al.
The Cochrane database of systematic reviews, (2)(2), CD006111-CD006111 (2007-04-20)
Sickle cell disease is one of the most common genetic disorders. Sickle cell crises in which irregular and dehydrated cells contribute to blocking of blood vessels are characterised by episodes of pain. Treatment is mainly supportive and symptomatic. In vitro
G J Hofmeyr et al.
The Cochrane database of systematic reviews, (2)(2), CD001064-CD001064 (2000-05-05)
Piracetam is thought to promote the metabolism of brain cells when they are hypoxic. It has been used to prevent adverse effects of fetal distress. The objective of this review was to assess the effects of piracetam for suspected fetal
A A Noorbala et al.
Journal of clinical pharmacy and therapeutics, 24(5), 369-374 (1999-12-03)
There is a growing interest in investigating the role of glutamate receptors in the pathophysiology of schizophrenia. Indeed, the hyperdopaminergic theory of schizophrenia can explain only the positive symptoms of schizophrenia, whereas the glutamate hypothesis may provide a more comprehensive
Measurement and correlation for the solubilities of cinnarizine, pentoxifylline, and piracetam in supercritical carbon dioxide
Lee, C, et al.
Fluid Phase Equilibria, 367(1), 182-187 (2014)
Mika H Martikainen et al.
Epileptic disorders : international epilepsy journal with videotape, 14(4), 438-441 (2012-12-19)
Epilepsy is a common manifestation of mitochondrial disease associated with mutations of the mitochondrial polymerase γ (POLG). Prognosis of mitochondrial epilepsy is often poor and there are few reports of successful treatment of POLG-related epilepsy. We describe a 26-year-old woman
Helge Bjørnæs et al.
Epilepsy & behavior : E&B, 27(1), 40-48 (2013-02-05)
We performed a double-blind placebo-controlled crossover study of the effects of spike activity during sleep and when awake on learning, long-term memory, vigilance and behavior before and after treatment with levetiracetam in children with electrical status epilepticus during sleep. At
Sawsan A Zaitone et al.
Indian journal of pharmacology, 44(6), 774-779 (2012-12-19)
To evaluate the neuroprotective effect of the nootropic drugs, piracetam (PIR) and vinpocetine (VIN), in rotenone-induced Parkinsonism in rats. Sixty male rats were divided into 6 groups of 10 rats each. The groups were administered vehicle, control (rotenone, 1.5 mg/kg/48
Eugen Trinka et al.
Journal of neurology, neurosurgery, and psychiatry, 84(10), 1138-1147 (2012-08-31)
To compare the effectiveness of levetiracetam (LEV) with extended-release sodium valproate (VPA-ER) and controlled-release carbamazepine (CBZ-CR) as monotherapy in patients with newly diagnosed epilepsy. This unblinded, randomised, 52-week superiority trial (NCT00175903) recruited patients (≥16 years of age) with ≥2 unprovoked
1/3