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关键词:'P6526'
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Aimee L Cunningham et al.
Virulence, 11(1), 283-294 (2020-04-04)
There is a need for development of an effective vaccine against Francisella tularensis, as this potential bioweapon has a high mortality rate and low infectious dose when delivered via the aerosol route. Moreover, this Tier 1 agent has a history
Crystal L Richards et al.
Microbial ecology, 76(1), 52-63 (2015-03-23)
Private residences in rural areas with water systems that are not adequately regulated, monitored, and updated could have drinking water that poses a health risk. To investigate water quality on the Crow Reservation in Montana, water and biofilm samples were
Shin-ichi Nishimura et al.
Journal of the American Chemical Society, 132(39), 13596-13597 (2010-09-14)
A new pyrophosphate compound Li(2)FeP(2)O(7) was synthesized by a conventional solid-state reaction, and its crystal structure was determined. Its reversible electrode operation at ca. 3.5 V vs Li was identified with the capacity of a one-electron theoretical value of 110
Anna E Champion et al.
Frontiers in cellular and infection microbiology, 8, 182-182 (2018-07-03)
Francisella tularensis is the etiologic agent of tularemia, and subspecies tularensis (type A) is the most virulent subspecies. The live vaccine strain (LVS) of subspecies holarctica produces a capsule-like complex (CLC) that consists of a large variety of glycoproteins. Expression
Sukalyani Banik et al.
PloS one, 10(6), e0130858-e0130858 (2015-06-23)
Francisella tularensis is a facultative intracellular pathogen, and is the causative agent of a fatal human disease known as tularemia. F. tularensis is classified as a Category A Biothreat agent by the CDC based on its use in bioweapon programs
Santiago Navas-Carretero et al.
Nutrition (Burbank, Los Angeles County, Calif.), 25(1), 20-24 (2008-08-30)
Preventing iron deficiency has been a main target of the World Health Organization since 1992. Difficulties to reach dietary recommended iron intakes and to enhance iron absorption should be overcome. We compared in iron-deficient women the bioavailability of iron of
Laura Rossi et al.
Food chemistry, 151, 243-247 (2014-01-16)
Ferric pyrophosphate is a widely used material in the area of mineral fortification but its synthesis and properties in colloidal form are largely unknown. In this article, we report on the synthesis and characterisation of colloidal iron(III) pyrophosphate particles with
Naresh Modepalli et al.
Pharmaceutical research, 30(3), 889-898 (2012-11-29)
Iontophoretic mediated transdermal delivery of ferric pyrophosphate (FPP) in combination with microneedle pretreatment was investigated as a potential treatment for iron deficiency anemia (IDA). In vitro transdermal delivery studies were performed using hairless rat skin and pharmacodynamic studies were performed
Maria Andersson et al.
The American journal of clinical nutrition, 88(5), 1378-1387 (2008-11-11)
Dual fortification of salt with iodine and iron could be a sustainable approach to combating iodine and iron deficiencies. We compared the efficacy of dual-fortified salt (DFS) made by using 2 proposed contrasting formulas-one fortifying with iron as micronized ground
Padmapriya P Banada et al.
Journal of clinical microbiology, 55(1), 291-301 (2016-11-17)
Francisella tularensis is a potential bioterrorism agent that is highly infectious at very low doses. Diagnosis of tularemia by blood culture and nucleic acid-based diagnostic tests is insufficiently sensitive. Here, we demonstrate a highly sensitive F. tularensis assay that incorporates
Perspective on Iron-Based Phosphate Cathode for Commercial Sodium-Ion Cells
Yajing Liu, et al
Small, 19, 2302972-2302972 (2023)
Padmapriya P Banada et al.
Journal of clinical microbiology, 57(5) (2019-03-08)
Francisella tularensis, Bacillus anthracis, and Yersinia pestis are tier 1 select agents with the potential to rapidly cause severe disease. Rapid detection of these bacteria from patient samples at the point of care could contribute to improved clinical outcomes in
Taoufik Ghrairi et al.
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica, 123(3), 260-268 (2015-01-06)
Pseudomonas strains isolated from hot spring water were tested for bacteriocin-like substance (BLS) production using a target panel of closely related microorganisms and other Gram-positive and Gram-negative bacteria. Molecular identification was carried out through specific PCR and 16S RNA sequence
Mark A Roe et al.
European journal of nutrition, 48(2), 115-119 (2009-01-15)
Food iron fortification is a sustainable and relatively simple strategy to reduce/prevent iron deficiency but is a challenge for the food industry because of possible adverse organoleptic changes caused by the added iron. A micronized dispersible ferric pyrophosphate, trademarked as
Siva Ram Kiran Vaka et al.
Pharmaceutical development and technology, 16(5), 483-488 (2010-06-16)
The objective of this study was to investigate the feasibility of rapid administration of iron via transdermal route as an alternative to parenteral route of administration. In vitro drug delivery studies were carried out using porcine epidermis mounted on Franz
H N Shivakumar et al.
Journal of drug targeting, 18(1), 36-44 (2009-07-29)
Bovine serum albumin (BSA) microspheres of ferric pyrophosphate (FPP) intended for passive targeting to the Peyer's patches has been proposed for oral iron supplementation. Microspheres prepared by emulsification chemical cross linking method were characterized for surface topography, entrapment efficiency, particle
Le Zhu et al.
Journal of agricultural and food chemistry, 57(11), 5014-5019 (2009-05-20)
Iron bioavailability from supplements and fortificants varies depending upon the form of the iron and the presence or absence of iron absorption enhancers and inhibitors. Our objectives were to compare the effects of pH and selected enhancers and inhibitors and
I Angeles-Agdeppa et al.
International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition, 78(2), 74-86 (2008-09-16)
Iron deficiency anemia (IDA) in the Philippines is a serious public health problem. Fortifying rice offers a great opportunity to control IDA. However, information on other types of fortificants that can be used is scarce. To compare the effects of
Jun Li et al.
Environmental science and pollution research international, 25(10), 9697-9707 (2018-01-26)
The results show that ozone concentration determination using ultraviolet spectrophotometry (UV-2450) at 258 nm is easier than using indigo method at 600 nm. A strong linear relationship was found between purge time and O3 concentration in deionized water. Ozone concentration can be
S Narasimha Murthy et al.
Journal of pharmaceutical sciences, 98(8), 2670-2676 (2009-01-01)
Transdermal delivery of iron can overcome the GI side effects and the discomfort associated with parenteral administration. Slow and prolonged transdermal delivery of iron would also avoid potential oversaturation of transferrin and overcome accumulation of free iron in the systemic
Christine Hotz et al.
Food and nutrition bulletin, 29(2), 140-149 (2008-08-13)
Universal fortification of staple foods with iron has been widely promoted as a cost-effective strategy to reduce iron deficiency in developing-country populations. Nonetheless, relatively few efficacy trials have been reported to date to demonstrate impact on iron status. The Ultra
Maria Andersson et al.
The American journal of clinical nutrition, 92(5), 1094-1104 (2010-09-17)
Random serial sampling is widely used in population pharmacokinetic studies and may have advantages compared with conventional fixed time-point evaluation of iron fortification. Our objective was to validate random serial sampling to judge the efficacy of iron fortification of a
Shoubin Sun et al.
Journal of ophthalmology, 2015, 425438-425438 (2015-08-11)
Ocular siderosis is a common eye disease caused by retention of an iron-containing intraocular foreign body in the eye. Iron-containing intraocular foreign bodies may cause severe inflammatory reaction and affect visual function. Currently the optimal treatment method of ocular siderosis
Tabassum Rahman et al.
Frontiers in immunology, 11, 1828-1828 (2020-09-29)
The NLRP3 inflammasome is central to host defense and implicated in various inflammatory diseases and conditions. While the favored paradigm of NLRP3 inflammasome activation stipulates a unifying signal intermediate that de-represses NLRP3, this view has not been tested. Further, structures
Seham M Rabadi et al.
The Journal of biological chemistry, 291(10), 5009-5021 (2015-12-09)
Francisella tularensis, the causative agent of a fatal human disease known as tularemia, has been used in the bioweapon programs of several countries in the past, and now it is considered a potential bioterror agent. Extreme infectivity and virulence of
Lena Davidsson et al.
The American journal of clinical nutrition, 89(6), 1815-1820 (2009-05-01)
Non-water-soluble iron compounds have been reported to be less well absorbed than ferrous sulfate in young children, and concern has been raised about their usefulness as food fortificants. The objective was to evaluate the usefulness of ferrous fumarate and ferric
Shaghayegh Papian et al.
Microbial pathogenesis, 147, 104396-104396 (2020-07-21)
Legionella pneumophila is a Gram-negative intracellular bacterium and causes legionnaire's disease an -atypical pneumonia in humans. Lipopolysaccharide (LPS) is the main antigen of Gram-negative bacteria but is less studied because of its carbohydrate nature. Here, we immunized mice with detoxified
Juan Francisco Haro-Vicente et al.
European journal of nutrition, 47(8), 470-478 (2008-10-28)
Food iron (Fe) fortification is an adequate approach for preventing Fe-deficiency anemia. Poorly water-soluble Fe compounds have good sensory attributes but low bioavailability. The reduction of the particle size of Fe fortificants and the addition of ascorbic acid might increase
Wilhelmina M Huston et al.
Microbes and infection, 10(5), 497-503 (2008-04-12)
Multicopper oxidases have been described to have functions in copper tolerance, manganese oxidation, and iron oxidation in a range of bacteria. The putative cytoplasmic membrane multicopper oxidase from Legionella pneumophila was investigated. The mcoL gene was found to be critical
Fatemeh Alaei Faradonbeh et al.
Srpski arhiv za celokupno lekarstvo, 143(5-6), 274-278 (2015-08-12)
Legionellapneumophila is the most commonly detected cause of legionellosis, which is an acute respiratory tract infection with high morbidity and mortality rates. The aim of this study was to investigate the prevalence rate of L. pneumophila in bronchoalveolar lavages and
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