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关键词:'P9630'
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Louise Clement et al.
International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition, 82(2), 130-136 (2012-10-16)
The purpose of this study was to evaluate the B-6 vitamers in plasma and related symptoms in hemodialysis subjects taking high- or low-dose vitamins. A total of 24 hemodialysis (HD) subjects were divided into two groups. Twelve subjects received a
Oivind Midttun et al.
Clinical chemistry, 51(7), 1206-1216 (2005-06-25)
Homocysteine, a risk factor of cardiovascular disease, cognitive disorders, and pregnancy complications, exists at a point of metabolic convergence of several B vitamins, including vitamins B(6) and B(2) (riboflavin). Measurement of the various forms of these vitamins may be useful
Xiaoxu Cheng et al.
Journal of separation science, 43(4), 727-735 (2019-11-26)
As an important Chinese medicine decoction, Wu-tou decoction has been used to treat rheumatic arthritis for more than a thousand years. We previously reported that the Wu-tou decoction could change the urinary and serum metabolites in adjuvant-induced arthritis rats significantly.
Antitumour Effects of 4?Pyridoxate Diammine Hydroxy Platinum, a Novel Cisplatin Derivative, Against Malignant Gliomas In?vitro and In?vivo: A Comparison with Cisplatin.
Tokunaga Y, et al.
Pharmacy and Pharmacology Communications, 3(7), 353-356 (1997)
Yi-Chia Huang et al.
European journal of nutrition, 42(2), 84-90 (2003-03-15)
Exclusion of animal products and having only plant protein in vegetarian diets may affect the status of certain B-vitamins, and further cause the elevation of plasma homocysteine concentration. The purpose of this study was to assess the status of homocysteine
Øivind Midttun et al.
The American journal of clinical nutrition, 86(1), 131-138 (2007-07-10)
Vitamin B-6 exists in different forms; one of those forms, pyridoxal 5'-phosphate (PLP), serves a cofactor in many enzyme reactions, including the transsulfuration pathway, in which homocysteine is converted to cystathionine and then to cysteine. Data on the relations between
D Majchrzak et al.
Annals of nutrition & metabolism, 50(6), 485-491 (2006-09-22)
A vegetarian diet is considered to promote health and longevity and reduce the risk of cardiovascular diseases and cancer. However, a vegetarian diet may be deficient in some nutrients. Exclusion of animal products in vegetarian diets may affect the status
Priscille G Massé et al.
The American journal of clinical nutrition, 80(4), 946-951 (2004-09-28)
Although many studies have reported reduced vitamin B-6 status with aging, little information is available about the specific effects of menopause. We aimed to examine vitamin B-6 metabolism in premenopausal and early postmenopausal women. We examined dietary intake and vitamin
Katsumi Shibata et al.
Nutrition and metabolic insights, 6, 51-57 (2013-01-01)
The objective of this study was to investigate whether the intake level of a staple food influences the nutritional status of water-soluble vitamins in pregnant Japanese women. Urinary excretion of water-soluble vitamins was used as a biomarker for nutritional assessment.
Sue-Joan Chang et al.
The Journal of nutrition, 132(10), 3130-3134 (2002-10-09)
The Estimated Average Requirement (EAR) and Recommended Dietary Allowance (RDA) of vitamin B-6 for children were recently estimated by extrapolating from adult values because of limited available information. To determine vitamin B-6 requirements and provide recommendations for intakes, vitamin B-6
Svetlana Dolina et al.
Medical hypotheses, 79(2), 157-164 (2012-06-01)
The study testifies an assumption on epilepsy as an inborn error of pyridoxine metabolism and suggests non-invasive quantitative biomarkers for clarified evaluation of clinical status and monitoring an individual treatment by antiepileptic drugs. Urinary parameters of pyridoxal-phosphate (PLP)-dependent tryptophan degradation
Michael E Rybak et al.
Analytical biochemistry, 333(2), 336-344 (2004-09-29)
A reversed-phase high-performance liquid chromatography (HPLC) method with fluorometric detection was developed for the routine determination of pyridoxal 5'-phosphate (PLP) and 4-pyridoxic acid (4-PA) in serum. Chlorite postcolumn derivatization was used to oxidize PLP to a more fluorescent carboxylic acid
Y-C Huang et al.
European journal of clinical nutrition, 56(5), 387-392 (2002-05-10)
To assess vitamin B6 intake and status of critically ill patients. The relationship between vitamin B6 status indicators and the severity of illness and outcome in these patients was also examined. Prospective clinical study. The study was performed at the
Michael E Rybak et al.
Analytical biochemistry, 388(1), 175-177 (2009-02-24)
Protein precipitation followed by centrifuge filtration was tested as a simplified sample preparation procedure for quantifying pyridoxal 5'-phosphate (PLP) and 4-pyridoxic acid (4PA) in serum by high-performance liquid chromatography. Serum samples (n=160) were prepared by both centrifuge filtration and an
J D Shoemaker et al.
Journal of chromatography, 562(1-2), 125-138 (1991-01-02)
Eighty-five clinical urine samples and nineteen urine samples previously found by other laboratories to suggest genetic metabolic defects were prepared for trimethylsilylation by treatment with urease, followed by azeotropic dehydration. The "Target Analyte Search" program provided with the VG Trio
Juan Xu et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 1136, 121884-121884 (2019-12-11)
A method for the simultaneous quantification of B vitamins and related amines in one-carbon (1C) metabolism would benefit the study of diet and genetic/epigenetic regulation of mammalian development and health. We present a validated method for the simultaneous quantitative analysis
Arve Ulvik et al.
The American journal of clinical nutrition, 95(5), 1072-1078 (2012-04-12)
A negative association between systemic markers of inflammation and plasma vitamin B-6 has been observed in population-based and patient cohorts; however, vitamin B-6 (pyridoxine) treatment has mostly failed to improve inflammatory indexes. We aimed to assess the effect of pyridoxine
Katsumi Shibata et al.
Journal of nutritional science and vitaminology, 51(6), 385-391 (2006-03-09)
To acquire the data concerning the tolerable upper intake level which prevents health problems from an excessive intake of pantothenic acid, an animal experiment was done. Rats of the Wistar strain (male, 3 wk old) were fed on a diet
Yi-Chia Huang et al.
Nutrition (Burbank, Los Angeles County, Calif.), 21(7-8), 779-785 (2005-06-25)
This study assessed the effect of vitamin B6 status on immune responses in mechanically ventilated, critically ill patients and compared the results with those of healthy controls. This was designed as a cross-sectional observational study. Forty patients in the intensive
Sweekruthi A Shetty et al.
Journal of chromatography. A, 1609, 460452-460452 (2019-08-25)
Absolute quantification of B-vitamins in milk is becoming imperative to correlate its impact on child/human health. In today's world of changing food habits and environmental pollution, there is concern if milk is what we think it to be. In the
Katsumi Shibata et al.
Nutrition and metabolic insights, 6, 1-10 (2013-08-13)
We aimed to determine the effects of vitamin B1 deficiency on vitamin contents of urine, liver, and blood. In the current study, rats were divided into 3 groups (n = 5, each group): the first was freely fed a complete
Gianfranco Frigerio et al.
Toxicology letters, 329, 56-66 (2020-05-08)
Although thousands of different chemicals have been identified in cigarette smoke, the characterization of their urinary metabolites still requires significant research. The aim of this work was to perform an untargeted metabolomic approach to a pilot cross-sectional study conducted on
V M Kodentsova et al.
Voprosy meditsinskoi khimii, 39(5), 29-33 (1993-09-01)
Increase of vitamin B6 derivatives by 36% in liver tissue, decrease in content of thiamine by 20%, of ascorbic acid--by 35%, of oxidized nicotinamide coenzymes--by 27%, simultaneously with a decrease in excretion of 1-methyl nicotinamide and 4-pyridoxic acid with urine
Karen L Ericson et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 823(2), 218-220 (2005-08-02)
The sensitivity of fluorescent detection of the biologically active form of Vitamin B-6, pyridoxal 5'-phosphate (PLP), in biological samples has been improved approximately four-fold by adopting chlorite as a post-column derivatization reagent (instead of bisulfite) in high-performance liquid chromatography (HPLC)
J A Driskell et al.
International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition, 70(5), 221-225 (2000-11-09)
The vitamin B-6 intakes and plasma B-6 vitamer levels of healthy nonsupplemented men and women, 19-24 and 25-50 years, were compared. The subjects did not take nutrient supplements or medications or use tobacco products. Subjects were grouped as follows: eight
K Schuster et al.
The American journal of clinical nutrition, 39(3), 466-470 (1984-03-01)
Urinary excretion of 4-pyridoxic acid (4PA) in 19 men (n = 5) and women (n = 14) was measured to evaluate the validity of determining the 4PA/creatinine ratio in random urine samples as an alternative to total 24-h 4PA excretion
M Jankowska et al.
Transplantation proceedings, 46(8), 2631-2635 (2014-11-09)
Vitamin B6 status has an impact on the body's inflammatory and immune responses. Immunosuppressive therapy may influence vitamin B6 metabolism in kidney transplant recipients. Treatment with polyclonal anti-thymocyte globulin (ATG) is associated with long-term changes in inflammatory and immune parameters.
Aya Moriya et al.
Journal of nutritional science and vitaminology, 64(6), 412-424 (2019-01-05)
The present study aims to determine the most suitable dietary balance of energy-producing nutrients for recovery from starvation. Rats were fed their standard high- carbohydrate diet (HCD, carbohydrate energy : protein energy : fat energy=71 : 18 : 11) for
J A Driskell et al.
Biomedical chromatography : BMC, 5(5), 198-201 (1991-09-01)
Plasma B-6 vitamer and plasma and urinary 4-pyridoxic acid concentrations of 21 young white women, 21-27 years, having radiomonitored pyridoxal 5'-phosphate and coenzyme stimulation of erythrocyte alanine aminotransferase activities indicative of adequate vitamin B-6 status were determined in an effort
Wei Zeng et al.
Biomedical chromatography : BMC, 34(4), e4795-e4795 (2020-01-23)
In this study, we focused on studying the changes in urine metabolites in hyperlipidemic rats using ultra-performance liquid chromatography coupled with quadrupole time-of-fight mass spectrometry (UPLC-Q-TOF/MS) and metabolomics, as well as the effect of Citri Reticulatae Chachiensis Pericarpium (CRCP) on
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