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PHR1447
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关键词:'PHR1447'
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Sabine Klein et al.
Neuropharmacology, 90, 53-62 (2014-12-03)
Despite more than 20 clinically approved antiepileptic drugs (AEDs), there remains a substantial unmet clinical need for patients with refractory (AED-resistant) epilepsy. Animal models of refractory epilepsy are needed for at least two goals; (1) better understanding of the mechanisms
Katherine A Lyseng-Williamson
CNS drugs, 25(10), 901-905 (2011-09-23)
Levetiracetam (Keppra®, E Keppra®) is an established second-generation antiepileptic drug (AED). Worldwide, levetiracetam is most commonly approved as adjunctive treatment of partial-onset seizures with or without secondary generalization; other approved indications include monotherapy treatment of partial-onset seizures with or without
Marte Helene Bjørk et al.
Epilepsia, 56(1), 28-39 (2014-12-20)
To assess incidence, prevalence, risk factors, and prognosis of peripartum depression and anxiety in a prospective study of women with epilepsy. Pregnancies in women with epilepsy (n=706) were compared to pregnancies in all women without epilepsy (n=106,511) including women with
Muhammad U Farooq et al.
American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 66(6), 541-561 (2009-03-07)
The role of levetiracetam in different epileptic, nonepileptic, neurologic, and psychiatric disorders is discussed. Levetiracetam, an antiepileptic drug (AED), was first approved as an adjunctive therapy for the treatment of partial epilepsy in adults. It is currently being used in
Reversed-phase HPLC analysis of levetiracetam in tablets using monolithic and conventional C18 silica columns.
Can NO and Arli G
Journal of AOAC (Association of Official Analytical Chemists) International, 93(4), 1077-1085 (2010)
Optimized and validated flow-injection spectrophotometric analysis of topiramate, piracetam and levetiracetam in pharmaceutical formulations
Hadad G, et al.
Acta pharmaceutica, 61(4), 377-389 (2011)
Fawzi A Babtain
Clinical neuropharmacology, 35(4), 201-202 (2012-07-19)
Levetiracetam was approved for generalized and partial epilepsy in pediatric and adult population. It is also an effective antimyoclonus, but the evidence only supports its use as an adjunctive agent along with other antiepileptic drugs, such as sodium valproate, and
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