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显示 1-30 共 179 条结果 关于 "PVP40" 范围 论文
Macromolecular Crowding as a Tool to Screen Anti-fibrotic Drugs: The Scar-in-a-Jar System Revisited.
Nataly Puerta Cavanzo et al.
Frontiers in medicine, 7, 615774-615774 (2021-02-02)
An unsolved therapeutic problem in fibrosis is the overproduction of collagen. In order to screen the effect of anti-fibrotic drugs on collagen deposition, the Scar-in-a-Jar approach has been introduced about a decade ago. With macromolecular crowding a rapid deposition of
Michael F Palopoli et al.
BMC evolutionary biology, 15, 93-93 (2015-05-23)
Although males and females need one another in order to reproduce, they often have different reproductive interests, which can lead to conflict between the sexes. The intensity and frequency of male-male competition for fertilization opportunities is thought to be an
Sung Neung Lee et al.
Archives of pharmacal research, 36(1), 79-85 (2013-01-19)
A novel surface-attached, spray-dried solid dispersion containing poorly water-soluble carvedilol (CV) without any change in the crystallinity was prepared using water, polyvinylpyrrolidone (PVP K30) and Tween 80. The solid dispersion was optimized by investigating the effects of the weight ratios
Michael G Mason et al.
Nature protocols, 15(11), 3663-3677 (2020-10-03)
The complexity of current nucleic acid isolation methods limits their use outside of the modern laboratory environment. Here, we describe a fast and affordable method to purify nucleic acids from animal, plant, viral and microbial samples using a cellulose-based dipstick.
Yan-Yan Yin et al.
Inorganic chemistry, 52(7), 3738-3743 (2013-03-20)
Both bulk crystals and nanocrystals of two helical complexes, [Cu(μ2-L)(H2O)]n (1) and {[Cu(μ2-L)(H2O)]·2H2O}n (2) (H2L = thiazolidine-2,4-dicarboxylic acid), have been synthesized with the chiralities of right-handedness (1) and left-handedness (2), respectively. 4-Cyanopyridine and poly(vinylpyrrolidone) (PVP) have been applied to control
Karin Weigel et al.
Journal of virology, 89(23), 11926-11934 (2015-09-18)
The selective accumulation of both DNA components of a bipartite geminivirus, Abutilon mosaic virus, was recorded during early systemic infection of Nicotiana benthamiana plants. Purified nuclei were diagnosed for viral DNA using hybridization specific for DNA A or DNA B
Helen Thomas et al.
Journal of chromatography. A, 1285, 48-56 (2013-03-16)
In protein chromatography, the size of the protein determines which fraction of pores it can access within a resin and at which rate of diffusion. Moreover, in the presence of grafted polymers like in advanced materials, adsorbed proteins and electrolytes
Gamal M El Maghraby et al.
Pharmaceutical development and technology, 19(6), 641-650 (2013-07-12)
Nisoldipine is a calcium channel blocker with low and variable oral bioavailability. This was attributed to slow dissolution and presystemic metabolism. Accordingly, the objective of this work was to enhance the dissolution rate of nisoldipine to formulate fast disintegrating tablets
J L Zamora
American journal of surgery, 151(3), 400-406 (1986-03-01)
The chemical, microbiologic, and toxic characteristics of povidone-iodine solution, a commonly used antiseptic agent, are addressed in a collective review of relevant works published from 1956 to the present. Interactions of this agent with the thyroid gland and the kidneys
Rafaela I S Ladeira-Ázar et al.
Applied biochemistry and biotechnology, 188(1), 29-42 (2018-10-06)
Considering bioethanol production, extensive research has been performed to decrease inhibitors produced during pretreatments, to diminish energy input, and to decrease costs. In this study, sugarcane bagasse was pretreated with NaOH, H2SO4, and water. The higher concentration of phenols, 3.3 g/L
Absence of Complex I Is Associated with Diminished Respiratory Chain Function in European Mistletoe.
Andrew E Maclean et al.
Current biology : CB, 28(10), 1614-1619 (2018-05-08)
Parasitism is a life history strategy found across all domains of life whereby nutrition is obtained from a host. It is often associated with reductive evolution of the genome, including loss of genes from the organellar genomes [1, 2]. In
Giuseppe Esposito et al.
Scientific reports, 7(1), 7735-7735 (2017-08-12)
Despite the effectiveness of combined anti-retroviral therapy, human immunodeficiency virus (HIV) infected-patients frequently report diarrhea and neuropsychological deficits. It is claimed that the viral HIV-1 Trans activating factor (HIV-1 Tat) protein is responsible for both diarrhea and neurotoxic effects, but
Bin Li et al.
Carbohydrate polymers, 92(2), 2033-2040 (2013-02-13)
Amorphous solid dispersions (ASD) of quercetin (Que) in cellulose derivative matrices, carboxymethylcellulose acetate butyrate (CMCAB), hydroxypropylmethylcellulose acetate succinate (HPMCAS), and cellulose acetate adipate propionate (CAAdP) were prepared with the goal of identifying an ASD that effectively increased Que aqueous solution
Yizhen Wan et al.
BMC evolutionary biology, 13, 141-141 (2013-07-06)
Grapes are one of the most economically important fruit crops. There are about 60 species in the genus Vitis. The phylogenetic relationships among these species are of keen interest for the conservation and use of this germplasm. We selected 309
Jannatul Ferdous et al.
PloS one, 10(3), e0118503-e0118503 (2015-03-21)
For accurate and reliable gene expression analysis using quantitative real-time reverse transcription PCR (qPCR), the selection of appropriate reference genes as an internal control for normalization is crucial. We hypothesized that non-coding, small nucleolar RNAs (snoRNAs)would be stably expressed in
Zhijie Yang et al.
Journal of the American Chemical Society, 138(10), 3493-3500 (2016-02-26)
The concept of template-confined chemical reactions allows the synthesis of complex molecules that would hardly be producible through conventional method. This idea was developed to produce high quality nanocrystals more than 20 years ago. However, template-mediated assembly of colloidal nanocrystals
Mianqi Xue et al.
Nanoscale, 5(5), 1803-1805 (2013-02-02)
Nano-dumbbells via electrospinning: controllable nano-dumbbells are fabricated via electrospinning. The weight block parts and the length of nanowires between them can be adjusted through changing the experimental conditions. This nanostructure enables ultralow-limit gas sensing properties of the resulting polypyrrole-based microsensor.
Sune Nørhøj Jespersen et al.
Journal of magnetic resonance (San Diego, Calif. : 1997), 300, 84-94 (2019-02-04)
Designing novel diffusion-weighted pulse sequences to probe tissue microstructure beyond the conventional Stejskal-Tanner family is currently of broad interest. One such technique, multidimensional diffusion MRI, has been recently proposed to afford model-free decomposition of diffusion signal kurtosis into terms originating
Yu-Tsai Yang et al.
Pharmaceutical development and technology, 19(7), 806-812 (2013-09-21)
The penta-ethyl ester prodrug of diethylenetriaminepentaacetic acid (DTPA), which exists as an oily liquid, was incorporated into a solid dispersion for oral administration by the solvent evaporation method using blends of polyvinylpyrrolidone (PVP), Eudragit® RL PO and α-tocopherol. D-optimal mixture
Andreas U Müller et al.
Nature communications, 10(1), 4653-4653 (2019-10-13)
In mycobacteria, transcriptional activator PafBC is responsible for upregulating the majority of genes induced by DNA damage. Understanding the mechanism of PafBC activation is impeded by a lack of structural information on this transcription factor that contains a widespread, but
Chen Lin et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 114, 330-338 (2013-06-22)
In this paper, we report a Re(I) complex of Re(CO)3(Cl-PYO)Br, where Cl-PYO stands for 2-(4-chlorophenyl)-5-(pyridin-2-yl)-1,3,4-oxadiazole, including its synthesis, identification, molecular structure, theoretical calculation and photophysical character. Re(CO)3(Cl-PYO)Br is found to be a yellow emitter with long excited state lifetime in
Eduard Butkevych et al.
Frontiers in microbiology, 11, 344-344 (2020-03-27)
Campylobacter jejuni is a widespread zoonotic pathogen and the leading bacterial cause of foodborne gastroenteritis in humans. Previous infection studies showed disruption of intercellular contacts, induction of epithelial apoptosis, and immune activation, all three contributing to intestinal barrier dysfunction leading
Bhupendra K Sen et al.
Bulletin of environmental contamination and toxicology, 93(5), 549-554 (2014-09-27)
The removal of phenolic compounds, i.e., o-cresol, m-cresol, and p-cresol from aqueous solution have been evaluated employing activated carbon (AC) coated with polymer supported iron nanoparticles (FeNPs). The synthesized FeNPs were characterized by scanning electron microscope and X-ray diffraction analysis.
Andrada Ianuş et al.
NeuroImage, 183, 934-949 (2018-08-27)
Microscopic diffusion anisotropy (μA) has been recently gaining increasing attention for its ability to decouple the average compartment anisotropy from orientation dispersion. Advanced diffusion MRI sequences, such as double diffusion encoding (DDE) and double oscillating diffusion encoding (DODE) have been
Martin Kuentz et al.
Drug development and industrial pharmacy, 39(9), 1476-1483 (2012-10-10)
An automated version of uniaxial powder flow testing has recently been developed and there is a need for experimental data from pharmaceutical powders. To compare the novel testing method with an annular shear cell using different pharmaceutical excipients. A particular
Dayton J Goodell et al.
PloS one, 9(5), e96522-e96522 (2014-05-07)
Binding of the Ca2+/calmodulin(CaM)-dependent protein kinase II (CaMKII) to the NMDA-type glutamate receptor (NMDAR) subunit GluN2B controls long-term potentiation (LTP), a form of synaptic plasticity thought to underlie learning and memory. Regulation of this interaction is well-studied biochemically, but not
Shanqiu Liu et al.
ACS nano, 14(2), 1623-1634 (2020-02-01)
We describe a successful strategy to substantially enhance cell nucleation efficiency in polymer foams by using designer nanoparticles as nucleating agents. Bare and poly(dimethylsilane) (PDMS)-grafted raspberry-like silica nanoparticles with diameters ranging from ∼80 nm to ∼200 nm were synthesized and
István Lázár et al.
Gels (Basel, Switzerland), 4(2) (2019-01-25)
Nanogold is widely used in many areas of physics and chemistry due to its environment-sensitive plasmon resonance absorption. The immobilization of gold nanoparticles in highly porous silica aerogel offers an attractive alternative to liquid gold solutions as they show a
Mo Zhu et al.
Fungal biology, 123(3), 218-230 (2019-02-26)
UV-C irradiation is known to compromise germination of Blumeria graminis conidia and to reduce powdery mildew infestation. However, only scarce information is available on the effects of UV-C irradiation on B. graminis appressorium formation. Applying a Formvar® resin-based in vitro system allowed
Sidona Sikorskaite et al.
Plant methods, 9, 31-31 (2013-07-28)
In this study, a protocol is described for rapid preparation of an enriched, reasonably pure fraction of nuclear proteins from the leaves of tobacco (Nicotiana tabacum), potato (Solanum tuberosum) and apple (Malus domestica). The protocol gives reproducible results and can
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