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Jun Li et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 49(10), 2706-2709 (2011-07-06)
Phenobarbital (PB) is an efficacious and well-studied hepatic tumor promoting agent. Nuclear factor-κB (NF-κB) is a transcription factor activated by reactive oxygen and is involved in cell proliferation and apoptosis. We previously found that PB activates NF-κB and that dietary
Safety assessment of the substance alpha-tocopherol acetate for use in food contact materials
Bolognesi C, et al.
EFSA Journal, 14(3), 4412-4412 (2016)
Ephraim F Trakhtenberg et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 34(21), 7361-7374 (2014-05-23)
The failure of the CNS neurons to regenerate axons after injury or stroke is a major clinical problem. Transcriptional regulators like Set-β are well positioned to regulate intrinsic axon regeneration capacity, which declines developmentally in maturing CNS neurons. Set-β also
Ye Zhang et al.
The journal of physical chemistry. A, 115(29), 8242-8247 (2011-06-17)
Photoionization is known to take place when α-tocopherol (TOH) is excited to the S(1) state in a polar medium. It has been previously suggested that TO(•) is formed only as a result of proton release by TOH(•+), a process that
Resveratrol liposomes and lipid nanocarriers: comparison of characteristics and inducing browning of white adipocytes
Zu Y, et al.
Colloids and Surfaces. B, Biointerfaces, 164, 414-423 (2018)
Phytantriol-based in situ liquid crystals with long-term release for intra-articular administration.
Yulin Chen et al.
AAPS PharmSciTech, 16(4), 846-854 (2015-01-13)
The purpose of this study was to develop an injectable in situ liquid crystal formulation for intra-articular (IA) administration, and in situ forming a viscous liquid crystalline gel with long-term release of sinomenine hydrochloride (SMH) upon water absorption. The pseudo-ternary
P C Allen et al.
Poultry science, 81(1), 41-48 (2002-03-12)
In two trials, broiler chickens, processed similarly to those placed in commercial operation, were fed, from 1 d of age, a range (13 to 200 ppm) of DL-alpha-tocopheryl acetate (VE-AC) levels, and the effects on the pathology of Eimeria maxima
Preparation of core-shell PAN nanofibers encapsulated ?-tocopherol acetate and ascorbic acid 2-phosphate for photoprotection.
Wu XM, Branford-White CJ, Yu DG, et al.
Colloids and Surfaces, B: Biointerfaces, 82, 247-252 (2011)
Streamlined duplex live-dead microplate assay for cultured cells
Pfeffer BA and Fliesler SJ
Experimental Eye Research, 161, 17-29 (2017)
Bernard F McDonald et al.
Pharmaceutical development and technology, 20(2), 211-218 (2013-11-29)
The purpose of this study was to develop a novel multipaticulate drug delivery technology suitable for the delivery of pre-solubilized celecoxib to the gastrointestinal tract and more specifically to the colon. The solubility of celecoxib in a range of oils
S K Linneen et al.
Journal of animal science, 93(8), 3941-3949 (2015-10-07)
Seven ruminally cannulated crossbred steers (BW = 720 ± 62 kg) were used in a randomized crossover design (4 periods, each 18 d) to evaluate in vivo rumen characteristics and apparent digestibility of steers consuming low-quality prairie hay and 1
Sylvain Losdat et al.
PloS one, 6(7), e22221-e22221 (2011-07-19)
Mounting an immune response against pathogens incurs costs to organisms by its effects on important life-history traits, such as reproductive investment and survival. As shown recently, immune activation produces large amounts of reactive species and is suggested to induce oxidative
Partial nutrient characterization of arugula (rocket-Eruca sativa L.) and the effect of heat treatment on its lipoxidase activity
Tassi EMM, et al.
Brazilian Journal of Food Technology, 21 (2018)
Effects of natural (RRR α-tocopherol acetate) or synthetic (all-rac α-tocopherol acetate) vitamin E supplementation on reproductive efficiency in beef cows.
Horn M, Gunn P, Van Emon M, et al.
Journal of Animal Science, 88, 3121-3127 (2011)
Vitamin E supplementation and cardiovascular events in high-risk patients.
Yusuf S, et al.
The New England Journal of Medicine, 342(3), 154-160 (2000)
Hiroyuki Kitajima et al.
Acta paediatrica (Oslo, Norway : 1992), 104(2), e82-e89 (2014-11-11)
Methods to improve the mental development of extremely low birthweight (ELBW) children are currently lacking. We assessed the effects of long-term supplementation of alpha-tocopherol on the neurological development of 259 school-aged ELBW children. Extremely low birthweight participants were divided into
Dorota Olender et al.
European journal of medicinal chemistry, 44(2), 645-652 (2008-07-02)
Some new nitroimidazole derivatives have been synthesized by treating 4,5-dinitro- and 2-methyl-4,5-dinitroimidazoles with epoxypropane, epichlorohydrin or phenacyl bromide in alkylation reactions. The nitro group in N-substituted 4,5-dinitro- and 2-methyl-4,5-dinitroimidazoles has been replaced with primary and secondary amines to afford 4-amino-5-nitroimidazole
Molecular mechanism of alpha-tocopherol action
Azzi A
Free radical biology & medicine, 43(1), 16-21 (2007)
Eiko Kato et al.
Bioorganic & medicinal chemistry, 19(21), 6348-6355 (2011-09-29)
The water-soluble vitamin E derivative, sodium dl-α-tocopheryl-6-O-phosphate (1), exhibits protective effects against skin damage. As reported herein, we investigated the actions of 1 on the formation of the inflammatory mediator, prostaglandin E(2) (PGE(2)), as compared to dl-α-tocopheryl acetate (2) and
Denis Fourches et al.
Chemical research in toxicology, 23(1), 171-183 (2009-12-18)
Drug-induced liver injury is one of the main causes of drug attrition. The ability to predict the liver effects of drug candidates from their chemical structures is critical to help guide experimental drug discovery projects toward safer medicines. In this
alpha-Tocopherol stereoisomers
Jensen S K and Lauridsen C
Vitamins and Hormones, 76, 281-308 (2007)
Absorption, transport, and tissue delivery of vitamin E
Rigotti A
Molecular Aspects of Medicine, 28(5-6), 423-436 (2007)
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