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显示 1-30 共 38 条结果 关于 "T5888" 范围 论文
P Fadda et al.
International journal of pharmaceutics, 446(1-2), 166-175 (2013-02-21)
Warm microemulsions (WME) containing lipids are used as starting systems to obtain solid lipid nanoparticles (SLN) in alternative processes to those based on high pressure homogenization technique. SLN characteristics can be influenced by the microemulsion composition and the specific conditions
Vidya Vaidyanathan et al.
American journal of physiology. Endocrinology and metabolism, 303(5), E624-E634 (2012-07-05)
The goal of this study was to determine whether administration of the CB₁ cannabinoid receptor antagonist rimonabant would alter fatty acid flux in nonhuman primates. Five adult baboons (Papio Sp) aged 12.1 ± 4.7 yr (body weight: 31.9 ± 2.1
Xinyue Dai et al.
Food & function, 11(2), 1869-1880 (2020-02-19)
This study aimed to quantify the short-chain fatty acids (SCFAs) and medium-chain fatty acids (MCFAs) in human milk triacylglycerols (TAGs) and investigate their concentrations in human milk consumed during lactation by infants born at different gestational ages. One hundred and
Transesterification to biodiesel with superhydrophobic porous solid base catalysts.
Fujian Liu et al.
ChemSusChem, 4(8), 1059-1062 (2011-06-01)
Remington: The Science and Practice of Pharmacy, 1 (2006)
Soheila Kashanian et al.
International journal of nanomedicine, 6, 2393-2401 (2011-11-25)
Solid lipid nanoparticles (SLNs) are colloidal carrier systems which provide controlled-release profiles for many substances. In this study, we prepared aqueous dispersions of lipid nanoparticles using a modified, pH-sensitive derivative of phosphatidylethanolamine. SLNs were prepared using polysorbate 80 as the
Mandar R Patel et al.
Journal of food science, 77(1), N8-13 (2012-01-21)
The use of solid lipid nanoparticles (SLNs) is a technique that has been widely used in the pharmaceutical industry for the last 2 decades and has become of increasing interest to food scientists due to its potential for encapsulation and
I Rivolta et al.
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 62(1), 45-53 (2011-04-01)
The aim of present work was to elucidate the interaction of solid lipid nanoparticles (SLNs) with cellular plasma-membrane to gain insight of intracellular drug delivery. To this aim we followed the uptake of coumarin-6 (a drug model) either free in
Hiromichi Nakahara
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 132(7), 817-822 (2012-07-14)
Lung surfactants (LS), a complex of ∼90 wt% lipids (mainly dipalmitoylphosphatidylcholine or DPPC) and ∼10 wt% surfactant proteins (SP-A, -B, -C, and -D), adsorb to an air-alveolar fluid interface and then lower its surface tension down to near zero during
Laure Gabert et al.
Rapid communications in mass spectrometry : RCM, 25(19), 2697-2703 (2011-09-14)
Lipid metabolism studies focus mainly on oxidation and storage but rarely on faecal elimination, which is needed to assess total lipid distribution during the postprandial period. The purpose of the present work was to set up and validate the analysis
Maike Windbergs et al.
Journal of pharmaceutical sciences, 99(3), 1464-1475 (2009-08-20)
In this study, in situ and mapping Raman spectroscopic measurements were used to investigate the physical structure of solid lipid extrudates and relate the structure to dissolution behaviour. Theophylline anhydrate was extruded with tripalmitin, with and without the water-soluble polymer
Starch, Lipid, and Protein Accumulation in Nutrient-Stressed Microalgal Cells Studied Using Fourier Transform Infrared Microscopy
Hastings G, et al.
Frontiers in Science, Technology, Engineering and Mathematics, 2(2), 1-1 (2018)
Gergely Szakonyi et al.
Acta pharmaceutica Hungarica, 82(2), 81-90 (2012-08-09)
Increasing number of new, innovative pharmaceutical products are in the generic market. One of the important dosage forms is the group of orally disintegrating products. The feature of these products is that they disintegrate rapidly in the mouth upon contact
Sriharsha Gupta Potta et al.
Journal of microencapsulation, 28(1), 74-81 (2010-12-22)
Solid lipid nanoparticles (SLNs) loaded with ibuprofen (IBU) were prepared by solvent-free high-pressure homogenization (HPH). The produced SLNs consisted of stearic acid, triluarin or tripalmitin as lipid matrixes and various stabilizers. The produced empty and IBU-loaded SLNs were characterized for
Ce Qi et al.
Journal of the science of food and agriculture, 92(4), 787-793 (2011-11-22)
High-purity soybean phosphatidylcholine (SPC) (94%) were prepared using macroporous resin adsorption chromatography previously. Catalase is a food enzyme for promoting health and protecting against many age-related disease. Solid lipid nanoparticles (SLN) are safe immobilizing systems for efficient protein transportation to
Jeoung Mae Son et al.
Journal of the science of food and agriculture, 90(9), 1520-1526 (2010-06-16)
Solvent fractionation is effective in improving separation at low temperature, resulting in higher yield and purity of the final product. Tripalmitin (PPP) is an important substrate for the synthesis of human milk fat substitute (HMFS). In this study a fraction
Ardalan Chaichi et al.
The Analyst, 146(1), 170-183 (2020-11-03)
Post-traumatic stress disorder (PTSD) is a widespread psychiatric injury that develops serious life-threatening symptoms like substance abuse, severe depression, cognitive impairments, and persistent anxiety. However, the mechanisms of post-traumatic stress injury in brain are poorly understood due to the lack
Anna Topolewska et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 990, 150-157 (2015-04-16)
Green leafy vegetables are valuable secondary sources of nutrients, including lipids, commonly consumed in developing countries. However, method development for the analysis of fatty acids is usually focused on the animal lipid samples, rarely including natural plant extracts. Hence, the
Danielle M Schwartz et al.
Journal of lipid research, 48(11), 2514-2520 (2007-08-25)
We have developed a reliable, rapid, and economical assay for the quantification of triacylglycerol (TG) in cells and animal tissues. In a few hours, this assay quantifies microgram amounts of TG from tens or even hundreds of samples. The protocol
Xiao-Li Qin et al.
Journal of agricultural and food chemistry, 60(9), 2377-2384 (2012-03-01)
Tripalmitin-enriched triacylglycerols were concentrated from palm stearin by acetone fractionation and as the substrate reacted with a mixture of equimolar quantities of fatty acids (C8:0-C18:3). The incorporation degree and acyl migration level of the fatty acids and acylglycerols composition were
Yung-Chih Kuo et al.
Colloids and surfaces. B, Biointerfaces, 88(2), 682-690 (2011-08-26)
Solid lipid nanoparticles (SLNs) with complex internal phase were fabricated for formulating stavudine (D4T), delavirdine (DLV), and saquinavir (SQV). The lipids including Compritol 888 ATO, tripalmitin, and cacao butter were stabilized by L-α-phospatidylcholine, cholesteryl hemisuccinate, and taurocholate to form SLNs.
Isothermal crystallization of tripalmitin in sesame oil
Dibildox-Alvarado E and Toro-Vazquez JF
Journal of the American Oil Chemists' Society, 74(2), 69-76 (1997)
Rehab Nabil Shamma et al.
Pharmaceutical development and technology, 17(5), 583-593 (2011-07-21)
Sustained release matrix pellets of the freely water soluble drug, betahistine dihydrochloride (BH), were prepared using freeze pelletization technique. Different waxes and lipids (cetyl alcohol, beeswax, glyceryl tripalmitate (GTP) and glyceryl tristearate) were evaluated for the preparation of matrix pellets.
Maike Windbergs et al.
AAPS PharmSciTech, 11(1), 2-8 (2010-03-24)
Extrudates based on varying ratios of the triglyceride tripalmitin and the hydrophilic polymer polyethylene glycol as matrix formers were produced as oral dosage forms with controlled release characteristics. The extrudates were processed below the melting points of the excipients and
Chang Li et al.
Journal of agricultural and food chemistry, 63(44), 9850-9854 (2015-10-20)
The capacities of six antioxidants to inhibit the formation of 3-monochloropropane-1,2 diol (3-MCPD) esters were examined in this study. Inhibitory capacities of the antioxidants were investigated both in chemical models containing the precursors (tripalmitoyl glycerol, 1,2-dipalmitoyl-sn-glycerol, monopalmitoyl glycerol, and sodium
Rieke Witzleb et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 77(1), 170-177 (2010-10-14)
The aim of this work was to develop a continuous solid lipid extrusion process that includes post-process milling of the extrudates. Die diameters smaller than 0.5 mm should be used for taste masking of the bitter tasting anthelmintic praziquantel. During
Soad A Yehia et al.
The Journal of pharmacy and pharmacology, 64(10), 1425-1437 (2012-09-05)
The purpose of this study was to develop an injectable depot liposphere delivery system with high loading capacity for controlled delivery of donepezil to decrease dosing frequency and increase patient compliance. A 3(2) full factorial design was employed to study
Maximilian Greiner et al.
Journal of agricultural and food chemistry, 60(20), 5243-5249 (2012-04-17)
Using molecular-dynamics (MD) simulations the densities and self-diffusion coefficients of a range of liquid monoacid triacylglycerides (TAGs) have been studied as a function of temperature and, for the first time, pressure. While offset by their ambient properties, the response of
Maike Windbergs et al.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 37(5), 555-562 (2009-05-02)
Different combinations of monoacid triglycerides and polyethylene glycol powders of different molecular weights were successfully extruded below their melting temperatures as a basis for oral dosage forms. The incorporated polyethylene glycols exhibiting different mean molecular weights were compared with respect
Ming-Jun Tsai et al.
International journal of pharmaceutics, 423(2), 461-470 (2011-12-24)
The objective of the present work was to investigate the specific brain targeting of baicalein by intravenous injection after incorporation into nanostructured lipid carriers (NLCs). The NLC system, composed of tripalmitin, Gelucires, vitamin E, phospholipids, and poloxamer 188 (referred to
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