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V2002
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Duodenal infusion of feces for recurrent Clostridium difficile.
Trevor C Van Schooneveld et al.
The New England journal of medicine, 368(22), 2143-2143 (2013-05-31)
Nickalus R Khan et al.
Journal of neurosurgery. Spine, 21(6), 974-983 (2014-09-27)
Surgical site infection (SSI) is a serious and costly complication of spinal surgery. There have been several conflicting reports on the use of intrawound vancomycin powder in decreasing SSI in spine surgery. The purpose of this study is to answer
Continuous infusion of vancomycin in neonates.
Anisa D Patel et al.
Archives of disease in childhood, 98(6), 478-479 (2013-04-02)
Dan Vershkov et al.
Cell reports, 26(10), 2531-2539 (2019-03-07)
Fragile X syndrome (FXS) is caused primarily by a CGG repeat expansion in the FMR1 gene that triggers its transcriptional silencing. In order to investigate the regulatory layers involved in FMR1 inactivation, we tested a collection of chromatin modulators for
Stephen W Davies et al.
The journal of trauma and acute care surgery, 75(5), 830-835 (2013-10-26)
Vancomycin is considered the drug of choice for methicillin-resistant Staphylococcus aureus infection; however, it has also been linked with nephrotoxicity in the past, sometimes leading to its substitution with linezolid. We hypothesized that patients treated with vancomycin for gram-positive (GP)
Treating Clostridium difficile infection.
Daniel M Shafran et al.
CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 186(7), 531-531 (2013-12-18)
Stacy E F Melanson et al.
American journal of clinical pathology, 140(6), 801-806 (2013-11-15)
Blood samples for vancomycin levels are often drawn too early, leading to potential misinterpretation of results. However, only a few studies describe interventions to reduce mistimed vancomycin levels. We implemented an information technology (IT)-based intervention that provided educational instructions to
Philip Storey et al.
Ophthalmology, 121(1), 283-289 (2013-10-23)
To compare the incidence of endophthalmitis after intravitreal injection with and without topical postinjection antibiotic prophylaxis. Retrospective case-control study. All patients treated with intravitreal injection of ranibizumab, bevacizumab, or aflibercept for a variety of retinal vascular diseases at a single
Máté Szász et al.
Acta microbiologica et immunologica Hungarica, 60(4), 461-468 (2013-12-03)
Biofilm-forming Staphylococcus epidermidis strains are common cause of the periprosthetic infection. The treatment of the periprosthetic infection is very problematic, so the prevention of these infections by an antibiotic containing prothesis could be an option for prevention.The purpose of the
Hiroto Inaba et al.
Cancer, 120(13), 1985-1992 (2014-03-29)
Intensive chemotherapy for pediatric acute myeloid leukemia incurs the risk of infectious complications, but the benefits of antibiotic prophylaxis remain unclear. In the current study, among 103 children treated on the AML02 protocol between October 2002 and October 2008 at
Kai Chen et al.
Journal of critical care, 30(1), 218-218 (2014-12-03)
The purpose of the study was to investigate the pharmacokinetics of combined intravenous (i.v.) and intracerebroventricular (i.c.v.) vancomycin for patients with intracranial infections after craniotomy and to provide the basis for establishing the intracranial local administration criterion. Fourteen postoperative intracranial
Ioannis M Zacharioudakis et al.
American journal of kidney diseases : the official journal of the National Kidney Foundation, 65(1), 88-97 (2014-07-22)
Vancomycin-resistant enterococci (VRE) have become important nosocomial pathogens causing outbreaks worldwide. Patients undergoing dialysis represent a vulnerable population due to their comorbid conditions, frequent use of antibacterial agents, and frequent contact with health care settings. Systematic review and meta-analysis of
Robert Krautz et al.
eLife, 9 (2020-12-31)
Postmitotic tissues are incapable of replacing damaged cells through proliferation, but need to rely on buffering mechanisms to prevent tissue disintegration. By constitutively activating the Ras/MAPK-pathway via RasV12-overexpression in the postmitotic salivary glands (SGs) of Drosophila larvae, we overrode the
Aseem Arif Shaikh et al.
Clinical orthopaedics and related research, 472(7), 2201-2207 (2014-03-07)
The treatment of knee arthritis with coexistent bone or joint sepsis is challenging. Despite the condition causing considerable morbidity, there is no generally agreed-upon approach to its treatment. We used aggressive débridement of the knee and implantation of intraoperatively molded
Vancomycin-induced interstitial nephritis superimposed on coexisting renal disease: the importance of renal biopsy.
Michael S Gelfand et al.
The American journal of the medical sciences, 347(4), 338-340 (2014-03-22)
Darren N Seril et al.
The American journal of gastroenterology, 109(7), 941-947 (2014-07-06)
Clostridium difficile (C. difficile) infection (CDI) following total proctocolectomy and ileal pouch-anal anastomosis has been increasingly recognized over the past 5 years. CDI of the ileal pouch has been recognized in ∼10% of symptomatic patients seen at a tertiary referral
Lam T Khuat et al.
Science translational medicine, 12(571) (2020-11-27)
The efficacy of allogeneic hematopoietic stem cell transplantation (allo-HSCT) is limited by acute and chronic graft-versus-host disease (GVHD). The impact of obesity on allo-HSCT outcomes is poorly understood. Here, we report that obesity had a negative and selective impact on
Paul A Muller et al.
Science (New York, N.Y.), 370(6514), 314-321 (2020-08-29)
The gut microbiota affects tissue physiology, metabolism, and function of both the immune and nervous systems. We found that intrinsic enteric-associated neurons (iEANs) in mice are functionally adapted to the intestinal segment they occupy; ileal and colonic neurons are more
Diffuse umbilicated vesicles in a critically ill child.
Laura Chang et al.
JAMA dermatology, 149(5), 641-642 (2013-05-17)
Collins Njie Ateba et al.
Journal of water and health, 11(4), 684-691 (2013-12-18)
A total of 22 groundwater samples were randomly collected from three rural communities in the Mafikeng area. Bile esculin agar was used for selective isolation of enterococci. Standard preliminary tests (Gram staining, oxidase test, catalase test) and confirmatory tests (Prolex™
Risk factors for vancomycin nephrotoxicity: still a matter of debate*.
Verônica T Costa e Silva et al.
Critical care medicine, 42(12), 2635-2636 (2014-11-18)
Filipe Cerca et al.
Journal of medical microbiology, 63(Pt 10), 1274-1283 (2014-07-24)
Staphylococcus epidermidis is the most commonly isolated aetiological agent of nosocomial infections, mainly due to its ability to establish biofilms on indwelling medical devices. Detachment of bacteria from S. epidermidis biofilms and subsequent growth in the planktonic form is a
Torsten S Boutrup et al.
Acta veterinaria Scandinavica, 52, 17-17 (2010-02-26)
Porcine proliferative enteropathy in pigs is caused by the obligate, intracellular bacterium Lawsonia intracellularis. In vitro studies have shown close bacterium-cell interaction followed by cellular uptake of the bacterium within 3 h post inoculation (PI). However, knowledge of the initial
Hadeel Al-Kofide et al.
Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 16(4), 245-250 (2009-12-18)
gram-positive infections are prevalent among cancer patients and vancomycin therapy is often initiated empirically. A typical vancomycin pharmacokinetics is observed in such patients. The aim of the study was to evaluate the pharmacokinetics of vancomycin in this patient population and
Peter A Haddad et al.
Artificial organs, 40(8), 804-810 (2015-12-30)
Biofilms are communities of bacteria that can cause infections which are resistant to the immune system and antimicrobial treatments, posing a significant threat for patients with implantable and indwelling medical devices. The purpose of our research was to determine if
Medical research. The promise of poop.
Jop de Vrieze
Science (New York, N.Y.), 341(6149), 954-957 (2013-08-31)
Mireia Uribe-Herranz et al.
The Journal of clinical investigation, 130(1), 466-479 (2019-12-10)
Alterations in gut microbiota impact the pathophysiology of several diseases, including cancer. Radiotherapy (RT), an established curative and palliative cancer treatment, exerts potent immune modulatory effects, inducing tumor-associated antigen (TAA) cross-priming with antitumor CD8+ T cell elicitation and abscopal effects.
Zuojia Chen et al.
Immunity, 54(1), 151-163 (2020-11-22)
The gastrointestinal tract is known as the largest endocrine organ that encounters and integrates various immune stimulations and neuronal responses due to constant environmental challenges. Enterochromaffin (EC) cells, which function as chemosensors on the gut epithelium, are known to translate
Ajay E Kuriyan et al.
American journal of ophthalmology, 157(4), 774-780 (2014-01-15)
To report the clinical settings, antibiotic susceptibilities, and outcomes of endophthalmitis caused by Streptococcus species. Retrospective, observational case series. Single-center study evaluating all patients with culture-positive endophthalmitis caused by Streptococcus species between January 1, 2000, and December 31, 2011. Study
Neelam Pushker et al.
American journal of ophthalmology, 156(1), 178-183 (2013-04-30)
To evaluate the role of oral corticosteroids as an anti-inflammatory adjunct in the treatment of orbital cellulitis. Prospective, comparative, single-masked, interventional clinical study. setting: Tertiary eye care center (All India Institute of Medical Sciences). study population: Patients with acute onset
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