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Emmanuelle Vulliet et al.
Environmental science and pollution research international, 21(12), 7512-7521 (2014-03-07)
To collect a complete dataset regarding the occurrence of organic substances in groundwater, this study presents the examination of 66 organic contaminants in the groundwater of overseas departments, including pesticides, pharmaceutical compounds, hormones and some industrial substances. The selective and
Vahid Mirshafiee et al.
Biomaterials, 75, 295-304 (2015-10-30)
Nanoparticles (NPs) are functionalized with targeting ligands to enable selectively delivering drugs to desired locations in the body. When these functionalized NPs enter the blood stream, plasma proteins bind to their surfaces, forming a protein corona that affects NP uptake
Malik Mukhtar et al.
Environmental monitoring and assessment, 187(8), 482-482 (2015-07-02)
The present studies were carried out to observe the dissipation pattern of chlorpyrifos on apple in Kashmir Valley. Persistence of chlorpyrifos in apple was studied following two applications rates of chlorpyrifos (Dursban 20 EC) at 200 g a.i. ha(-1) (single dose
Ju-Hye Lee et al.
Food chemistry, 141(3), 3241-3249 (2013-07-23)
There is an increasing surplus of tomatoes that are abandoned due to their failure to meet customer standards. Therefore, to allow both value additions and the effective reuse of surplus tomatoes, we developed tomato vinegar (TV) containing phytochemicals and evaluated
Ana Gil-Bona et al.
Journal of proteome research, 14(1), 142-153 (2014-11-05)
The commensal fungus Candida albicans secretes a considerable number of proteins and, as in different fungal pathogens, extracellular vesicles (EVs) have also been observed. Our report contains the first proteomic analysis of EVs in C. albicans and a comparative proteomic
E Yenilmez et al.
Die Pharmazie, 70(2), 67-73 (2015-05-23)
In the present study chitosan based gel formulations containing Egg Yolk Oil (EYO) and Epidermal Growth Factor (EGF) were formulated successfully aiming at enhanced topical treatment of dermal burns the combination of traditional approaches with modern drug delivery systems. Physicochemical
Temmei Ito et al.
Biomedical materials (Bristol, England), 10(1), 015025-015025 (2015-03-03)
In order to obtain a hydroxyapatite (HAp)-poly(ethylene glycol) (PEG) composite, tetra amine-terminated PEG was crosslinked using disuccinimidyl tartrate to obtain a PEG hydrogel. Using two kinds of chelators with different stability constants for Ca ion (N-(2-hydroxyethyl) ethylenediamine-N,N',N'-triacetic acid (EDTA-OH, 8.14)
S A Kim et al.
Journal of food protection, 78(12), 2233-2239 (2015-11-29)
This study investigated changes in the microbial composition of microbrewed beer during the manufacturing processes and identified potential microbial hazards, effective critical quality control points, and potential contamination routes. Comprehensive quantitative (aerobic plate count, lactic acid bacteria, fungi, acetic acid
Kiranj K Chaudagar et al.
Clinical and experimental hypertension (New York, N.Y. : 1993), 36(8), 557-566 (2014-02-05)
Telmisartan possesses endothelial protective effects due to angiotensin II type 1 receptor antagonist, peroxisome proliferator-activated receptor γ (PPARγ) agonist and antioxidant action. Therefore, our objective was to study effect of telmisartan on angiogenic responsiveness of coronary endothelial cells (cECs) of
Shudipto K Dishari et al.
Biotechnology progress, 31(5), 1280-1286 (2015-06-18)
Virus filtration can provide a robust method for removal of adventitious parvoviruses in the production of biotherapeutics. Although virus filtration is typically thought to function by a purely size-based removal mechanism, there is limited data in the literature indicating that
Hwang Eui Cho et al.
Biomedical chromatography : BMC, 28(12), 1624-1632 (2014-05-02)
A sensitive and specific high-performance liquid chromatography-tandem mass spectrometry (LC-MS/MS) method was developed for the determination of Grayanotoxin I (GTX I) and Grayanotoxin III (GTX III) in rat whole blood. Grayanotoxins (GTXs) and clindamycin as internal standard (IS) were extracted
Asma Khoobi et al.
The Analyst, 139(16), 4064-4072 (2014-06-24)
A highly sensitive electrochemical nanosensor was developed using covalent modification of a glassy carbon electrode (GCE) by self-assembly of a novel Schiff base. Scanning electron microscopy (SEM) and electrochemical techniques were used to investigate the immobilization of the self-assembled monolayer
Joseph O Rich et al.
Bioresource technology, 196, 347-354 (2015-08-11)
Bacterial contaminants can inhibit ethanol production in biofuel fermentations, and even result in stuck fermentations. Contaminants may persist in production facilities by forming recalcitrant biofilms. A two-year longitudinal study was conducted of bacterial contaminants from a Midwestern dry grind corn
Latrice D Faulkner et al.
Endocrinology, 156(4), 1372-1385 (2015-01-16)
Proopiomelanocortin (POMC)-derived peptides like α-melanocyte-stimulating hormone (MSH) substantially improve hepatic insulin sensitivity and regulate energy expenditure. Melanocortinergic agents are also powerful inducers of sexual arousal that are being investigated for a possible therapeutic role in erectile dysfunction. It is currently
Shuying Huo et al.
Dalton transactions (Cambridge, England : 2003), 43(41), 15328-15336 (2014-07-31)
L-Selenomethionine (SeMet), the predominant form of selenium acquired from the diet by humans, has been used as a supplement, and exhibit some important functions like cancer prevention and antioxidative defense. Its interactions with Pt(II) anticancer drugs have been characterized, but
T Biron-Shental et al.
Placenta, 36(2), 199-203 (2014-12-17)
The intrauterine environment, including the placenta, is influenced by a variety of factors, among which is diabetes during pregnancy. These factors can affect lifetime morbidity. Senescence is a state of cellular metabolic arrest, known to be correlated with age-related diseases
Xin Zhu et al.
Antimicrobial agents and chemotherapy, 59(6), 3008-3017 (2015-03-11)
The antipseudomonal efficiency and mechanism of action of a novel engineered antimicrobial peptide, T9W, were evaluated in this study. T9W displayed high activity, with a lethal concentration (LC) of 1 to 4 μM against Pseudomonas aeruginosa, including against ciprofloxacin-, gentamicin-
Ismail M Fareez et al.
International journal of biological macromolecules, 72, 1419-1428 (2014-12-03)
The vulnerability of probiotics at low pH and high temperature has limited their optimal use as nutraceuticals. This study addressed these issues by adopting a physicochemical driven approach of incorporating Lactobacillus plantarum LAB12 into chitosan (Ch) coated alginate-xanthan gum (Alg-XG)
Claudia Dietze et al.
Analytical and bioanalytical chemistry, 407(29), 8735-8743 (2015-09-24)
A fast and straightforward method to prototype microfluidic chip systems for dead-volume-free hyphenation to electrospray-ionisation mass spectrometry is presented. The developed approach based on liquid-phase lithography provides an inexpensive and reliable access to microfluidic chips for MS coupling which can
Jiheng Li et al.
International journal of biological macromolecules, 72, 1097-1103 (2014-12-03)
The molecular aggregation of collagen solution (Col) in the presence of glycerol (Col-G) and 2-propanol (Col-P) was investigated. The transition temperature (Tm) of collagen, determined by ultra-sensitive differential scanning calorimetry, increased proportionally to the concentration of glycerol about 0.929 °C
Meiling Ye et al.
Nanoscale research letters, 9(1), 642-642 (2014-12-19)
Nano-sized particles are known to interfere with drug-metabolizing cytochrome P450 (CYP) enzymes, which can be anticipated to be a potential source of unintended adverse reactions, but the mechanisms underlying the inhibition are still not well understood. Herein we report a
Mohamed Abdel-Tawab Korany et al.
Journal of chromatographic science, 52(8), 837-847 (2013-09-06)
A novel high performance liquid chromatographic (HPLC) method with a pre-column derivatization reaction has been developed and validated. The method was used for the determination of the aminoglycoside antibiotic amikacin sulphate (AMK) in the presence of its synthetic precursor kanamycin
Mary-Rus Martínez-Cuenca et al.
PloS one, 10(7), e0134372-e0134372 (2015-08-01)
This work provides insight into several mechanisms involved in boron (B) regulation pathway in response to high B conditions in Citrus. The study was carried out in Citrus macrophylla W. (Cm) seedlings cultured "in vitro" in media with 50 or
Lucília N Diogo et al.
European journal of pharmacology, 765, 58-67 (2015-08-21)
Animal models of chronic intermittent hypoxia (CIH) mimic the hypertension observed in patients with obstructive sleep apnoea. Antihypertensive drugs were applied to these animal models to address the physiological mechanism but not to revert established hypertension. We aimed to investigate
Huijuan Zhang et al.
Biomaterials, 37, 353-366 (2014-12-03)
Artesunate (AS) is an iron-dependent drug, which has been used extensively as anti-malarial drugs worldwide with no obvious side effects. Recently, studies have shown that AS also possess profound cytotoxicity against tumor cells. However, simultaneous delivery of hydrophobic AS and
De Lu Zhang et al.
Aquatic toxicology (Amsterdam, Netherlands), 157, 215-224 (2014-12-03)
Aphanizomenon flos-aquae is a cyanobacterium that produces neurotoxins or paralytic shellfish poisons (PSPs) called aphantoxins, which present threats to environmental safety and human health via eutrophication of water bodies worldwide. Although the molecular mechanisms of this neurotoxin have been studied
Narges Naseri et al.
Carbohydrate polymers, 109, 7-15 (2014-05-13)
The aim of this study was to develop electrospun chitosan/polyethylene oxide-based randomly oriented fiber mats reinforced with chitin nanocrystals (ChNC) for wound dressing. Microscopy studies showed porous mats of smooth and beadless fibers with diameters between 223 and 966 nm.
David B Neau et al.
The Journal of biological chemistry, 289(46), 31905-31913 (2014-09-19)
Lipoxygenases (LOX) play critical roles in mammalian biology in the generation of potent lipid mediators of the inflammatory response; consequently, they are targets for the development of isoform-specific inhibitors. The regio- and stereo-specificity of the oxygenation of polyunsaturated fatty acids
Antoine Larrieu et al.
Nature communications, 6, 6043-6043 (2015-01-17)
Activated forms of jasmonic acid (JA) are central signals coordinating plant responses to stresses, yet tools to analyse their spatial and temporal distribution are lacking. Here we describe a JA perception biosensor termed Jas9-VENUS that allows the quantification of dynamic
Lesley Johnston et al.
Analytical and bioanalytical chemistry, 407(16), 4535-4540 (2015-04-12)
Most methods reported in the literature for determination of nitrofuran metabolites use the same extraction and derivatisation conditions to hydrolyse and extract the protein-bound residues from animal tissue. While undertaking certification of reference materials for nitrofuran metabolites in freeze-dried prawn
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