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Tatiane de Oliveira Souza Senra et al.
Parasitology research, 112(4), 1461-1466 (2013-01-29)
The acaricidal activity of carvacrol, (E)-cinnamaldehyde, trans-anethole, and linalool was studied on Rhipicephalus microplus and Dermacentor nitens larvae. All the substances were tested at concentrations of 2.5, 5.0, 10.0, 15.0, and 20.0 μl/ml, with 10 repetitions per treatment. The modified
Ida B Niklasson et al.
Contact dermatitis, 68(3), 129-138 (2013-02-21)
Cinnamyl alcohol and cinnamal are frequent fragrance contact allergens. Both are included in the European baseline fragrance mix I, which is used for screening of contact allergy in dermatitis patients. The aim of this study was to investigate the autoxidation
Katherine R Zodrow et al.
Langmuir : the ACS journal of surfaces and colloids, 28(39), 13993-13999 (2012-09-04)
Biofilm-associated infections are one of the leading causes of death in the United States. Although infections may be treated with antibiotics, the overuse of antibiotics has led to the spread of antibiotic resistance. Many natural antimicrobial compounds derived from edible
Manuel Hitzler et al.
Toxicology in vitro : an international journal published in association with BIBRA, 27(6), 1659-1669 (2013-04-30)
Dendritic cells (DCs) exhibit the unique capacity to induce T cell differentiation and proliferation, two processes that are crucially involved in allergic reactions. By combining the exclusive potential of DCs as the only professional antigen-presenting cells of the human body
M Lisa Manier et al.
Journal of mass spectrometry : JMS, 49(8), 665-673 (2014-07-22)
Imaging mass spectrometry (IMS) studies increasingly focus on endogenous small molecular weight metabolites and consequently bring special analytical challenges. Since analytical tissue blanks do not exist for endogenous metabolites, careful consideration must be given to confirm molecular identity. Here, we
J Cocchiara et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 43(6), 867-923 (2005-04-07)
A toxicologic and dermatologic review of cinnamaldehyde when used as a fragrance ingredient is presented.
Michael Theurer et al.
Phytomedicine : international journal of phytotherapy and phytopharmacology, 20(12), 1119-1123 (2013-07-06)
Trans-cinnamaldehyde, a component of leaves from Cinnamomum osmophloeum kaneh, has been shown to counteract tumor growth. The substance exerts its effect at least in part by triggering apoptosis. The propapoptotic signaling involves altered gene expression and mitochondrial depolarization. In analogy
Erika Parkinson et al.
Toxicological sciences : an official journal of the Society of Toxicology, 142(1), 239-249 (2014-08-26)
The risk of contact sensitization is a major consideration in the development of new formulations for personal care products. However, developing a mechanistic approach for non-animal risk assessment requires further understanding of haptenation of skin proteins by sensitizing chemicals, which
Thomas Voets et al.
Nature chemical biology, 1(2), 85-92 (2006-01-13)
Drosophila melanogaster flies carrying the trp (transient receptor potential) mutation are rapidly blinded by bright light, because of the absence of a Ca2+-permeable ion channel in their photoreceptors. The identification of the trp gene and the search for homologs in
Burdock GA
Encyclopedia of Food and Color Additives, 1, 590-591 (1997)
Ping Shao et al.
Carbohydrate polymers, 135, 27-34 (2015-10-11)
Emulsifying properties of water soluble polysaccharides from Ulva fasciata (UFP) were evaluated in cinnamaldehyde/water emulsions in terms of droplet size distribution, rheological properties, visual phase separation, and zeta-potential. The cinnamaldehyde/water (10%, wt/wt) emulsions were formulated and stabilized by different concentrations
L Blavi et al.
Journal of animal science, 94(12), 5262-5271 (2017-01-04)
The early exposure of the fetus to certain volatiles may result in a further preference for these compounds later in life and could positively affect the acceptance of feed containing a similar flavor and the zootechnical responses. The study consisted
Kirtee D Wani et al.
PloS one, 9(9), e107315-e107315 (2014-10-01)
Cinnamaldehyde, the bioactive component of the spice cinnamon, and its derivatives have been shown to possess anti-cancer activity against various cancer cell lines. However, its hydrophobic nature invites attention for efficient drug delivery systems that would enhance the bioavailability of
Lindsey J Macpherson et al.
Nature, 445(7127), 541-545 (2007-01-24)
The nervous system senses peripheral damage through nociceptive neurons that transmit a pain signal. TRPA1 is a member of the Transient Receptor Potential (TRP) family of ion channels and is expressed in nociceptive neurons. TRPA1 is activated by a variety
Neera Singh et al.
British journal of clinical pharmacology, 65(3), 418-422 (2007-12-21)
Isoniazid is the most widely used first line antituberculosis drug. It is considered safe during lactation, but limited data are available on the transfer of isoniazid from circulation to milk in lactating women, which can provide an assessment of extent
Yaoqi Tian et al.
Carbohydrate polymers, 91(2), 586-589 (2012-11-06)
In this study, the high-amylose corn starch-cinnamaldehyde inclusion complex was prepared by an ultrasound treatment and its releasing characteristic was investigated. The results showed that the ultrasound treatment (35°C, 10min and 250W) generated a higher encapsulation rate of 40.2% than
Fengge Shen et al.
Parasitology research, 110(4), 1321-1326 (2012-02-22)
The acaricidal activity of trans-cinnamaldehyde was evaluated in vitro on Psoroptes cuniculi. In this study, different concentrations of trans-cinnamaldehyde were tested, and the observed mites mortality was compared with that observed in untreated and treated (Acacerulen R®) controls. The morphological
Juane Li et al.
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan, 32(3), 446-452 (2013-01-10)
To investigate the effects of cinnamaldehyde (CA), an active and major compound in cinnamon, on glucose metabolism and insulin resistance in C57BLKS/J db/db mice. Sixteen male C57BLKS db/db mice were randomly divided into control and CA treatment groups. CA was
Jolanta Janiszewska et al.
Bioorganic & medicinal chemistry letters, 22(3), 1388-1393 (2012-01-11)
A series of new cationic lipopeptides containing branched, amphiphilic polar head derived from (Lys)Lys(Lys) dendron and C(8) or C(12) chain at C-end were designed, synthesized and characterized. Antimicrobial in vitro activity expressed as minimal inhibitory concentration (MIC) was evaluated against
Hyeeun Kwon et al.
The American journal of Chinese medicine, 43(4), 621-636 (2015-06-30)
Cinnamomum cassia bark has been used in traditional herbal medicine to treat a variety of cardiovascular diseases. However, the antiproliferative effect of cinnamon extract on vascular smooth muscle cells (VSMCs) and the corresponding restenosis has not been explored. Hence, after
Gabriela Trevisan et al.
Naunyn-Schmiedeberg's archives of pharmacology, 387(7), 679-689 (2014-04-12)
The transient receptor potential ankyrin 1 (TRPA1) has been identified as a relevant target for the development of novel analgesics. Gallic acid (GA) is a polyphenolic compound commonly found in green tea and various berries and possesses a wide range
Hnin Thanda Aung et al.
Bioorganic & medicinal chemistry, 19(7), 2392-2396 (2011-03-11)
In our previous paper, we reported that rosmarinic acid (1) of Argusia argentea could neutralize snake venom induced hemorrhagic action. Rosmarinic acid (1) consists of two phenylpropanoids: caffeic acid (2) and 3-(3,4-dihydroxyphenyl)lactic acid (3). In this study, we investigated the
Joungyoun Noh et al.
Nature communications, 6, 6907-6907 (2015-04-22)
Cancer cells, compared with normal cells, are under oxidative stress associated with the increased generation of reactive oxygen species (ROS) including H2O2 and are also susceptible to further ROS insults. Cancer cells adapt to oxidative stress by upregulating antioxidant systems
Amrita A Nagle et al.
PloS one, 7(11), e50125-e50125 (2012-11-28)
Multifunctional trans-cinnamaldehyde (CA) and its analogs display anti-cancer properties, with 2-benzoyloxycinnamaldehyde (BCA) and 5-fluoro-2-hydroxycinnamaldehyde (FHCA) being identified as the ortho-substituted analogs that possess potent anti-tumor activities. In this study, BCA, FHCA and a novel analog 5-fluoro-2-benzoyloxycinnamaldehyde (FBCA), were demonstrated to
Soo-Jin Jeong et al.
Biological & pharmaceutical bulletin, 38(3), 425-434 (2015-03-12)
Gyejibokryeong-hwan (GJBRH; Keishi-bukuryo-gan in Japan and Guizhi Fuling Wan in China) is a traditional herbal formula comprising five medicinal herbs and is used to treat climacteric syndrome. GJBRH has been shown to exhibit biological activity against diabetes, diabetic nephropathy, atherosclerosis
Juliana Cavalcante de Moura et al.
British journal of pharmacology, 171(18), 4289-4299 (2014-05-23)
Transient receptor potential vanilloid 1 (TRPV1) and TRP ankyrin 1 (TRPA1) are involved in many biological processes, including nociception and hyperalgesia. Whereas the involvement of TRPV1 in psychiatric disorders such as anxiety and depression has been reported, little is known
C E Chapman et al.
Journal of dairy science, 100(3), 1712-1719 (2017-01-04)
The objective of this 70-d study was to determine the effects of the essential oil cinnamaldehyde compared with the ionophore monensin on performance of weaned Holstein dairy heifers. Eighty-four Holstein dairy heifers (91 ± 3.33 d of age; 109 ±
Tran Minh Ngoc et al.
Journal of natural products, 72(6), 1205-1208 (2009-06-27)
A methanol extract of the twigs of Cinnamomum cassia was found to possess inhibitory activity against tyrosinase. Purification of the MeOH extract afforded four new phenolics, cassiferaldehyde (6), icariside DC (9), cinnacassinol (10), and dihydrocinnacasside (13), together with 10 known
E-Hyun Shin et al.
Journal of medical entomology, 50(3), 579-584 (2013-06-28)
Leptotrombidium pallidum (Nagoya, Miyagawa, Mitamura & Tamiya) is a primary vector of Orientia tsutsugamushi (Hyashi), the causative agent of scrub typhus. An assessment is made of the repellency to L. pallidum larvae (chiggers) of cassia bark, eucalyptus, and star anise
Venkadesaperumal Gopu et al.
PloS one, 10(8), e0134684-e0134684 (2015-08-08)
Quorum sensing (QS) plays a vital role in regulating the virulence factor of many food borne pathogens, which causes severe public health risk. Therefore, interrupting the QS signaling pathway may be an attractive strategy to combat microbial infections. In the
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