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Bruna Fernanda Murbach Teles Andrade et al.
The Journal of pharmacy and pharmacology, 66(10), 1491-1496 (2014-06-18)
In traditional medicine, plants have formed the basis of sophisticated systems that have been in existence for thousands of years and still provide mankind with new remedies. Cymbopogon martinii, known as palmarosa, has been used in aromatherapy as a skin
A Gallardo et al.
Journal of medical entomology, 49(2), 332-335 (2012-04-13)
The major components of geranium (Geranium maculatum L.) oil and their mixtures were tested against female Pediculus humanus capitis De Geer (Phthiraptera: Pediculidae). Chemical analysis by gas chromatography coupled to mass spectrometry revealed four major constituents: citronellol (38%), geraniol (16%)
Ramasamy S Annadurai et al.
BMC genomics, 13, 663-663 (2012-11-28)
Phyto-remedies for diabetic control are popular among patients with Type II Diabetes mellitus (DM), in addition to other diabetic control measures. A number of plant species are known to possess diabetic control properties. Costus pictus D. Don is popularly known
Frauke Lüddeke et al.
Applied and environmental microbiology, 78(7), 2128-2136 (2012-01-31)
Castellaniella defragrans is a Betaproteobacterium capable of coupling the oxidation of monoterpenes with denitrification. Geraniol dehydrogenase (GeDH) activity was induced during growth with limonene in comparison to growth with acetate. The N-terminal sequence of the purified enzyme directed the cloning
Jong Hyun Lee et al.
Cancer letters, 360(2), 280-293 (2015-02-24)
Aberrant activation of signal transducer and activator of transcription 3 (STAT3) is frequently observed in multiple myeloma (MM) cancer and can upregulate the expression of several genes involved in proliferation, survival, metastasis, and angiogenesis. The effect of farnesol (FOH) on
Alexander M Boutanaev et al.
Proceedings of the National Academy of Sciences of the United States of America, 112(1), E81-E88 (2014-12-17)
Plants produce an array of specialized metabolites, including chemicals that are important as medicines, flavors, fragrances, pigments and insecticides. The vast majority of this metabolic diversity is untapped. Here we take a systematic approach toward dissecting genetic components of plant
A Lapczynski et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 46 Suppl 11, S160-S170 (2008-07-22)
A toxicologic and dermatologic review of geraniol when used as a fragrance ingredient is presented.
Peter J McNamara et al.
Antimicrobial agents and chemotherapy, 53(5), 1898-1906 (2009-02-19)
Menstrual toxic shock syndrome is a rare but potentially life-threatening illness manifest through the actions of Staphylococcus aureus toxic shock syndrome toxin 1 (TSST-1). Previous studies have shown that tampon additives can influence staphylococcal TSST-1 production. We report here on
Luca Narduzzi et al.
Journal of agricultural and food chemistry, 63(30), 6823-6834 (2015-07-15)
We analyzed via untargeted UHPLC-ESI-Q-TOF-MS the metabolome of the berry tissues (skin, pulp, seeds) of some American Vitis species (Vitis cinerea, Vitis californica, Vitis arizonica), together with four interspecific hybrids, and seven Vitis vinifera cultivars, aiming to find differences in
Christine Wittig et al.
PloS one, 10(7), e0131946-e0131946 (2015-07-15)
Geraniol exerts several direct pharmacological effects on tumor cells and, thus, has been suggested as a promising anti-cancer compound. Because vascularization is a major precondition for tumor growth, we analyzed in this study the anti-angiogenic action of geraniol. In vitro
Gavin L Sacks et al.
Journal of agricultural and food chemistry, 60(12), 2998-3004 (2012-03-09)
1,1,6-Trimethyl-1,2-dihydronaphthalene (TDN) is well-known to contribute "petrol" aromas to aged Riesling wines, but its prevalence and contribution to young Riesling or non-Riesling wines is not well understood. TDN concentrations were measured in 1-3-year-old varietal wines produced from Cabernet franc (n
Seung Hwan Lee et al.
Biosensors & bioelectronics, 74, 554-561 (2015-07-21)
Various attempts have been made to mimic the human olfactory system using human olfactory receptors (hORs). In particular, OR-expressed cell-based odorant detection systems mimic the smell sensing mechanism of humans, as they exploit endogenous cellular signaling pathways. However, the majority
Characteristic flavor of Kamho-shochu (sweet potato spirit).
Ohta T, et al.
Agricultural and Biological Chemistry, 54(6), 1353-1357 (1990)
Emilie Deletre et al.
Parasites & vectors, 8, 316-316 (2015-06-13)
Laboratory and field studies showed that repellent, irritant and toxic actions of common public health insecticides reduce human-vector contact and thereby interrupt disease transmission. One of the more effective strategies to reduce disease risk involves the use of long-lasting treated
San Zeng et al.
Pharmaceutical research, 32(8), 2548-2558 (2015-02-13)
Citral is composed of a random mixture of two geometric stereoisomers geranial (trans-citral) and neral (cis-citral) yet few studies have directly compared their in vivo antitumor properties. A micelle formulation was therefore developed. Geranial and neral were synthesized. Commercially-purchased citral
Martin Holm Rau et al.
BMC genomics, 16, 1051-1051 (2015-12-15)
Bacterial small RNAs (sRNAs) are recognized as posttranscriptional regulators involved in the control of bacterial lifestyle and adaptation to stressful conditions. Although chemical stress due to the toxicity of precursor and product compounds is frequently encountered in microbial bioprocessing applications
Yukihiro Yamamoto et al.
Bioorganic & medicinal chemistry letters, 18(14), 4044-4046 (2008-06-17)
In order to prepare functional phospholipids in the medical and pharmaceutical fields, perillyl alcohol, myrtenol, and nerol were transphosphatidylated via phospholipase D in an aqueous system. The yields of phosphatidyl-perillyl alcohol, -myrtenol, and -nerol were 79 mol %, 87 mol
Michael Linnen et al.
Bioprocess and biosystems engineering, 37(10), 2121-2129 (2014-05-02)
CelTherm is a biochemical process to produce renewable fuels and chemicals from lignocellulosic biomass. The present study's objective was to determine the level of treatment/purity of the microbial triacylglyceride oil (TAG) necessary to facilitate fuel production. After a unique microbe
Thirapit Subongkot et al.
International journal of nanomedicine, 10, 4581-4592 (2015-08-01)
The purpose of this study was to investigate the effect of ultradeformable liposome components, Tween 20 and terpenes, on vesicle fluidity. The fluidity was evaluated by electron spin resonance spectroscopy using 5-doxyl stearic acid and 16-doxyl stearic acid as spin
Naoko Sato-Masumoto et al.
Phytochemistry, 104, 12-20 (2014-05-28)
Studies on the biosynthesis of oil compounds in Perilla will help in understanding regulatory systems of secondary metabolites and in elucidating reaction mechanisms for natural product synthesis. In this study, two types of alcohol dehydrogenases, an aldo-keto reductase (AKR) and
Karamkolly R Rekha et al.
Chemico-biological interactions, 217, 57-66 (2014-04-29)
Parkinson's disease (PD) is a common disabling movement disorder owing to progressive depletion of dopamine in nigrostriatal region, and can be experimentally accelerated by the neurotoxin 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine (MPTP). MPTP-treated mice are a representative animal model for searching
Joachim Morrens et al.
Neuron, 106(1), 142-153 (2020-02-07)
Dopamine neurons mediate the association of conditioned stimuli (CS) with reward (unconditioned stimuli, US) by signaling the discrepancy between predicted and actual reward during the US. Some theoretical models suggest that learning is also influenced by the salience or associability
Damien Steyer et al.
Food microbiology, 33(2), 228-234 (2012-12-04)
Geraniol produced by grape is the main precursor of terpenols which play a key role in the floral aroma of white wines. We investigated the fate of geraniol during wine fermentation by Saccharomyces cerevisiae. The volatile compounds produced during fermentation
Muthukumaran Jayachandran et al.
Molecular and cellular biochemistry, 398(1-2), 39-53 (2014-09-15)
Hyperlipidemia is a major, modifiable risk factor for atherosclerosis and cardiovascular disease. In the present study, we have focused on the effect of different doses of geraniol (GOH) on the lipid profile and lipid metabolizing enzymes in atherogenic diet (AD)
Derek R Artz et al.
PloS one, 10(8), e0135688-e0135688 (2015-08-15)
There is a growing body of empirical evidence showing that wild and managed bees are negatively impacted by various pesticides that are applied in agroecosystems around the world. The lethal and sublethal effects of two widely used fungicides and one
Alexandra Veyrac et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 35(19), 7575-7586 (2015-05-15)
In search for the mechanisms underlying complex forms of human memory, such as episodic recollection, a primary challenge is to develop adequate animal models amenable to neurobiological investigation. Here, we proposed a novel framework and paradigm that provides means to
Lina Hagvall et al.
Contact dermatitis, 67(1), 20-27 (2012-06-12)
The fragrance terpene geraniol forms sensitizing compounds via autoxidation and skin metabolism. Geranial and neral, the two isomers of citral, are the major haptens formed in both of these activation pathways. To investigate whether testing with oxidized geraniol detects more
Amélie Slegers et al.
Molecules (Basel, Switzerland), 20(6), 10980-11016 (2015-06-18)
Developed from crosses between Vitis vinifera and North American Vitis species, interspecific hybrid grape varieties are becoming economically significant in northern areas, where they are now extensively grown for wine production. However, the varietal differences between interspecific hybrids are not
Bertrand Fouks et al.
The Journal of experimental biology, 216(Pt 2), 285-291 (2012-10-06)
Foraging is a result of innate and acquired mechanisms, and is optimized in order to increase fitness. During foraging, an animal faces many threats, such as predation and infection. The uptake of parasites and diseases while foraging is common and
Maizom Hassan et al.
Bioscience, biotechnology, and biochemistry, 76(8), 1463-1470 (2012-08-11)
NADP(+)-dependent geraniol dehydrogenase (EC 1.1.1.183) is an enzyme that catalyzes the oxidation of geraniol to geranial. Stable, highly active cell-free extract was obtained from Polygonum minus leaves using polyvinylpolypyrrolidone, Amberlite XAD-4, glycerol, 2-mercaptoethanol, thiourea, and phenylmethylsulfonylfluoride in tricine-NaOH buffer (pH
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