WH0001269M1

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关键词:'WH0001269M1'

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Emerging therapeutic targets in cancer induced bone disease: A focus on the peripheral type 2 cannabinoid receptor.

Marino S and Idris A

Pharmacological Research, 119, 391-403 (2017)

Common polymorphisms in the cannabinoid CB2 receptor gene (CNR2) are not associated with myocardial infarction and cardiovascular risk factors.

Reinhard W, et al.

International Journal of Molecular Medicine, 22, 165-174 (2008)

Cancer-Cachexia-Induced Human Skeletal Muscle Myotube Degeneration Is Prevented via Cannabinoid Receptor 2 Agonism In Vitro.

John Noone et al.

Pharmaceuticals (Basel, Switzerland), 16(11) (2023-11-25)

Cachexia syndrome, leading to reduced skeletal muscle and fat mass, is highly prevalent in cancer patients, resulting in further negative implications for these patients. To date, there is no approved therapy for cachexia syndrome. The objective of this study was

Sex-dependent influence of chronic mild stress (CMS) on voluntary alcohol consumption; study of neurobiological consequences

Marco EM, et al.

Pharmacology, Biochemistry, and Behavior, 152, 68-80 (2017)

Diversity Revealed by a Novel Family of Cadherins Expressed in Neurons at a Synaptic Complex

Kohmura N, et al.

Neuron, 20, 1137-1151 (1998)

Cannabinoid Receptor Type 1 Expression in the Developing Avian Retina: Morphological and Functional Correlation With the Dopaminergic System.

Luzia da Silva Sampaio et al.

Frontiers in cellular neuroscience, 12, 58-58 (2018-04-18)

The avian retina has been used as a model to study signaling by different neuro- and gliotransmitters. It is unclear how dopaminergic and cannabinoid systems are related in the retina. Here we studied the expression of type 1 and 2

Maternal high-fat diet decreases milk endocannabinoids with sex-specific changes in the cannabinoid and dopamine signaling and food preference in rat offspring.

Dias-Rocha, et al.

Frontiers in Endocrinology, 14, 1087999-1087999 (2023)

Role of the endocannabinoid system in the control of mouse myometrium contractility during the menstrual cycle

Pagano E, et al.

Biochemical Pharmacology, 124, 83-93 (2017)

The cannabinoid WIN 55,212-2 decreases specificity protein transcription factors and the oncogenic cap protein eIF4E in colon cancer cells.

Sandeep Sreevalsan et al.

Molecular cancer therapeutics, 12(11), 2483-2493 (2013-09-14)

2,3-Dihydro-5-methyl-3-([morpholinyl]methyl)pyrollo(1,2,3-de)-1,4-benzoxazinyl]-[1-naphthaleny]methanone [WIN 55,212-2, (WIN)] is a synthetic cannabinoid that inhibits RKO, HT-29, and SW480 cell growth, induced apoptosis, and downregulated expression of survivin, cyclin D1, EGF receptor (EGFR), VEGF, and its receptor (VEGFR1). WIN also decreased expression of specificity protein

Multiple osteoporosis susceptibility genes on chromosome 1p36 in Chinese.

Huang QY

Bone, 44, 984-988 (2009)

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