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显示 1-30 共 14522 条结果 关于 "X100" 范围 论文
Mohsen Saeedi et al.
Journal of environmental management, 214, 204-214 (2018-03-12)
The effects of soil components such as clay minerals and as humic acids, as well as co-existing metals and polycyclic aromatic hydrocarbons, on desorption and mobility are examined. Three types of artificially blended clay and clay mineral mixtures (pure kaolinite
Samantha T Clark et al.
Colloids and surfaces. B, Biointerfaces, 187, 110609-110609 (2019-12-07)
The effects of lipid charge and head group size on liposome partitioning by detergents is an important consideration for applications such as liposomal drug delivery or proteoliposome formation. Yet, the solubilization of mixed-lipid liposomes, those containing multiple types of lipids
Weiling Zou et al.
Analytical and bioanalytical chemistry, 413(5), 1429-1440 (2021-01-07)
The sensitive chitosan (CTS) detection methods based on the resonance Rayleigh scattering (RRS) quenching method and fluorescence quenching of Eosin Y were put forward. In the HAC-NaAC buffer solution, Eosin Y interacted with Triton X-100 to generate the binary complex
Marta Vignola et al.
Water research, 143, 66-76 (2018-06-26)
Rapid quantification of absolute microbial cell abundances is important for a comprehensive interpretation of microbiome surveys and crucial to support theoretical modelling and the design of engineered systems. In this paper, we propose a protocol specifically optimised for the quantification
Roberto Gaetani et al.
Tissue engineering. Part C, Methods (2018-11-07)
Different approaches have investigated the effects of the different extracellular matrices (ECMs) and 3D culture on islets function, showing encouraging results. Ideally, the proper scaffold should mimic the biochemical composition of the native tissue as it drives numerous signaling pathways
Alejandro Ropolo et al.
Frontiers in endocrinology, 11, 411-411 (2020-07-14)
Autophagy is an evolutionarily preserved degradation process of cytoplasmic cellular constituents, which participates in cell response to disease. We previously characterized VMP1 (Vacuole Membrane Protein 1) as an essential autophagy related protein that mediates autophagy in pancreatic diseases. We also
Luis Muniz-Feliciano et al.
Autophagy, 13(12), 2072-2085 (2017-09-22)
Macroautophagy/autophagy is an intracellular stress survival and recycling system whereas phagocytosis internalizes material from the extracellular milieu; yet, both pathways utilize lysosomes for cargo degradation. Whereas autophagy occurs in all cells, phagocytosis is performed by cell types such as macrophages
Huanyu Zhang et al.
Molecular oncology, 15(2), 725-738 (2020-11-24)
Pancreatic cancer (PC) is one of the most common human malignancies worldwide and remains a major clinical challenge. Here, we found that benproperine phosphate (BPP), a cough suppressant, showed a significant anticancer effect on PC both in vitro and in vivo via
Matthew Faulkner et al.
Nanoscale, 9(30), 10662-10673 (2017-06-16)
Carboxysomes are proteinaceous organelles that play essential roles in enhancing carbon fixation in cyanobacteria and some proteobacteria. These self-assembling organelles encapsulate Ribulose 1,5-bisphosphate carboxylase/oxygenase (Rubisco) and carbonic anhydrase using a protein shell structurally resembling an icosahedral viral capsid. The protein
Bindu P Nair et al.
Materials science & engineering. C, Materials for biological applications, 52, 333-342 (2015-05-09)
Scaffolds that can provide the requisite biological cues for the fast regeneration of bone are highly relevant to the advances in tissue engineering and regenerative medicine. In the present article, we report the fabrication of a chitosan-gelatin-siloxane scaffold bearing interpolymer-siloxane
Seolsong Kim et al.
Autophagy, 16(7), 1200-1220 (2019-08-31)
Hypothalamic glial cells named tanycytes, which line the 3rd ventricle (3V), are components of the hypothalamic network that regulates a diverse array of metabolic functions for energy homeostasis. Herein, we report that TSPO (translocator protein), an outer mitochondrial protein, is
Ruizhi He et al.
Toxicology and applied pharmacology, 356, 159-171 (2018-08-08)
The lysosome is emerging as a central regulator of the autophagic process, which plays a critical role in tumor growth and chemoresistance. Alantolactone, which is a natural compound produced by Inula helenium, has been shown to induce apoptosis in numerous
Diba Bagheri et al.
Reproductive biology, 18(3), 295-300 (2018-06-09)
Low oxygen concentrations during in vitro embryo development not only improving the embryo quality but also can lead to successful implantation. Yet, there is no investigation at the molecular level to indicate the association between increased implantation rate and invasive
Magdalena Olbryt et al.
Investigational new drugs, 35(5), 545-555 (2017-04-19)
Anthracycline chemotherapeutics, e.g. doxorubicin and daunorubicin, are active against a broad spectrum of cancers. Their cytotoxicity is mainly attributed to DNA intercalation, interference with topoisomerase activity, and induction of double-stranded DNA breaks. Since modification of anthracyclines can profoundly affect their
Zhiming Chen et al.
OncoTargets and therapy, 12, 8125-8138 (2019-11-07)
Upregulation of CXCL8 (C-X-C motif ligand 8) in tumor cells has been reported in several types of cancer, and it correlates with a poor prognosis. However, the role of CXCL8 in glioma progression remains unknown. In this study, we examined
Virginia Hargest et al.
Viruses, 13(3) (2021-03-07)
Since the 1970s, eight closely related serotypes of classical human astroviruses (HAstV) have been associated with gastrointestinal illness worldwide. In the late 2000s, three genetically unique human astrovirus clades, VA1-VA3, VA2-VA4, and MLB, were described. While the exact disease associated
Fernanda M Faturi et al.
Muscle & nerve, 53(1), 118-126 (2015-05-12)
Stretching (St) has been used for treating denervated muscles. However, its effectiveness and safety claims require further study. Rats were divided into: (1) those with denervated (D) muscles, evaluated 7 or 15 days after sciatic nerve crush injury; (2) those
Tomohiro Umeda et al.
Acta neuropathologica communications, 5(1), 59-59 (2017-08-02)
The E693Δ (Osaka) mutation in APP is linked to familial Alzheimer's disease. While this mutation accelerates amyloid β (Aβ) oligomerization, only patient homozygotes suffer from dementia, implying that this mutation is recessive and causes loss-of-function of amyloid precursor protein (APP).
Silas Maniatis et al.
Science (New York, N.Y.), 364(6435), 89-93 (2019-04-06)
Paralysis occurring in amyotrophic lateral sclerosis (ALS) results from denervation of skeletal muscle as a consequence of motor neuron degeneration. Interactions between motor neurons and glia contribute to motor neuron loss, but the spatiotemporal ordering of molecular events that drive
Hong Nhan Tran et al.
Advanced science (Weinheim, Baden-Wurttemberg, Germany), 7(21), 2002395-2002395 (2020-11-12)
A charge transport layer based on transition metal-oxides prepared by an anhydrous sol-gel method normally requires high-temperature annealing to achieve the desired quality. Although annealing is not a difficult process in the laboratory, it is definitely not a simple process
Maria Camilla Ciardulli et al.
International journal of molecular sciences, 21(16) (2020-08-23)
Mesenchymal stem cells derived from human bone marrow (hBM-MSCs) are utilized in tendon tissue-engineering protocols while extra-embryonic cord-derived, including from Wharton's Jelly (hWJ-MSCs), are emerging as useful alternatives. To explore the tenogenic responsiveness of hBM-MSCs and hWJ-MSCs to human Growth
Cheng-Li Lin et al.
Biological procedures online, 22, 20-20 (2020-09-05)
Ligamentum flavum hypertrophy (LFH) is among the most crucial factors in degenerative lumbar spinal stenosis, which can cause back pain, lower extremity pain, cauda equina syndrome and neurogenic claudication. The exact pathogenesis of LFH remains elusive despite extensive research. Most
Anna Aulicino et al.
BMC genomics, 16, 1046-1046 (2015-12-15)
Mycobacterium abscessus (MAB) is an emerging pathogen causing pulmonary infections in those with inflammatory lung disorders, such as Cystic Fibrosis (CF), and is associated with the highest fatality rate among rapidly growing mycobacteria (RGM). Phenotypically, MAB manifests as either a
Haiqiong Wang et al.
Science advances, 5(2), eaav4971-eaav4971 (2019-02-23)
Injured axons undergo a controlled, self-destruction process, known as Wallerian degeneration. However, the underlying mechanism remains elusive. Using the Drosophila wing nerve as a model, we identify the ESCRT component Vps4 as a previously unidentified essential gene for axonal integrity.
Yin Li et al.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 92, 544-553 (2017-06-04)
This study aims to investigate the effects of PI3K/AKt/mTOR signaling pathway on the proliferation and apoptosis in acute liver failure (ALF) by chaperone mediated autophagy (CMA). The hepatocytes extracted from both normal rats and rats with ALF were assigned to
Grégoire Chevalier et al.
Nature communications, 11(1), 6363-6363 (2020-12-15)
Depression is the leading cause of disability worldwide. Recent observations have revealed an association between mood disorders and alterations of the intestinal microbiota. Here, using unpredictable chronic mild stress (UCMS) as a mouse model of depression, we show that UCMS
Priya Singh et al.
Chemistry (Weinheim an der Bergstrasse, Germany), 25(41), 9728-9736 (2019-05-08)
Enzyme-mediated catalysis is attributed to enzyme-substrate interactions, with models such as "induced fit" and "conformational selection" emphasizing the role of protein conformational transitions. The dynamic nature of the protein structure, thus, plays a crucial role in molecular recognition and substrate
X Leng et al.
Domestic animal endocrinology, 67, 28-36 (2019-01-25)
Many studies have shown positive effects of prostaglandins (PGs) on various steps of skeletal muscle formation such as myoblast proliferation and myotube hypertrophy. In animals, PGs are synthesized through the action of the rate-limiting enzymes cyclooxygenase (COX) -1 and COX-2
Naoko Toki et al.
Nucleic acids research, 48(20), 11626-11644 (2020-11-02)
SINEUPs are long non-coding RNAs (lncRNAs) that contain a SINE element, and which up-regulate the translation of target mRNA. They have been studied in a wide range of applications, as both biological and therapeutic tools, although the underpinning molecular mechanism
Nayoung Lee et al.
Proteomics, 19(17), e1900086-e1900086 (2019-07-19)
Mitogen-activated protein (MAP) kinase signaling is critical for various cellular responses, including cell proliferation, differentiation, and cell death. The MAP kinase cascade is conserved in the eukaryotic kingdom as a three-tiered kinase module-MAP kinase kinase kinase, MAP kinase kinase, and
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