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Hong-Kyun Kim et al.
Dental materials journal, 34(4), 508-515 (2015-08-04)
The aim of this study was to compare osseointegration and surface characteristics of zirconia implants made by the powder injection molding (PIM) technique against those made by the conventional milling procedure in rabbit tibiae. Surface characteristics of 2 types of
H J Kang et al.
Asian-Australasian journal of animal sciences, 28(8), 1187-1193 (2015-06-25)
This study determined the effects of dietary restriction on growth and the expression of lipid metabolism and growth hormone signaling genes in the longissimus dorsi muscle (LM) of Korean cattle. Thirty-one Korean cattle steers (average age 10.5 months) were allocated
Ellen T Arena et al.
Proceedings of the National Academy of Sciences of the United States of America, 112(25), E3282-E3290 (2015-06-10)
Few studies within the pathogenic field have used advanced imaging and analytical tools to quantitatively measure pathogenicity in vivo. In this work, we present a novel approach for the investigation of host-pathogen processes based on medium-throughput 3D fluorescence imaging. The
Hyeryun Shin et al.
PloS one, 16(9), e0257395-e0257395 (2021-09-18)
Sensory experience modulates proliferation, differentiation, and migration of oligodendrocyte progenitor cells (OPCs). In the mouse primary visual cortex (V1), visual deprivation-dependent modulation of OPCs has not been demonstrated. Here, we demonstrate that undifferentiated OPCs developmentally peaked around postnatal day (P)
Ori Furman et al.
Theriogenology, 82(8), 1165-1172 (2014-09-13)
This study establishes an experimental model for subclinical mastitis induced by Gram-positive (G+) exosecretions of Staphylococcus aureus origin or Gram-negative (G-) endotoxin of Escherichia coli origin to examine its effects on follicular growth and steroid concentrations in Holstein dairy cows.
Tomohiro Makino et al.
Biochemical pharmacology, 171, 113717-113717 (2019-11-22)
Heritable disorders associated with hemoglobin production are the most common monogenic disorders. These are mainly represented by disorders such as β-thalassemia and sickle cell disease. Induction of fetal hemoglobin (HbF) has been known to ameliorate the clinical severity of these
Vasilios S Liarakos et al.
European journal of ophthalmology, 24(3), 299-308 (2013-11-19)
To evaluate the effect of subconjunctival anti-vascular endothelial growth factor (VEGF) ranibizumab on corneal and anterior segment neovascularization. In this experimental study and laboratory investigation, chemical cauterization was utilized to induce corneal neovascularization in 16 rabbits randomly divided in 2
Pain
Handbook of Veterinary Neurology (2011)
Hoon Dong Kim et al.
Investigative ophthalmology & visual science, 56(1), 122-131 (2014-12-17)
To evaluate the changes of retinal function with multifocal electroretinogram (mfERG), and estimate the association between functional and structural changes after selective retina therapy (SRT) with microsecond-pulsed laser in comparison to continuous wave laser photocoagulation (cwPC). Selective retina therapy and
Zhi-Yang Chang et al.
PloS one, 8(1), e55291-e55291 (2013-02-06)
This study aimed to evaluate the neuroprotective effect of EPO in the presence of N-methyl-d-aspartate (NMDA)-, trophic factor withdrawal (TFW)-, and tumor necrosis factor-alpha (TNF-α)-induced toxicity on total, small, and large retinal ganglion cells (RGCs). Retinal cells from adult rats
Burak Turgut et al.
Clinical & experimental ophthalmology, 43(1), 67-76 (2014-05-08)
To investigate the effects of subconjunctivally administered trastuzumab on wound healing in experimental glaucoma filtration surgery. Comparative, experimental study. Twenty eight eyes. Twenty-eight male New Zealand white rabbits were randomly assigned to four groups, each including seven rabbits: The rabbits
I H Murai et al.
Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 26(4), 1395-1404 (2015-01-15)
Evidence suggests that creatine may have some beneficial effects on bone. The study aimed to investigate the effects of exercise alone or combined with creatine on bone health in ovariectomized rats. Findings show that exercise, but not creatine, has an
N Pluchino et al.
Steroids, 95, 104-110 (2015-01-18)
Estetrol (E4), a naturally occurring estrogen produced exclusively by human fetal liver, is currently being evaluated for potential use in contraception and menopausal care in humans. The present study was designed to profile E4 effects on the central nervous system
Mehmet K Kaya et al.
Clinical & experimental ophthalmology, 43(5), 449-457 (2015-02-03)
The aim of this study was to compare the effects of lapatinib and trastuzumab on vascular endothelial growth factor on experimental corneal neovascularization. A total of 35 Wistar albino rats were randomly divided into five groups, each containing seven animals.
S L Jones et al.
Hormones and behavior, 73, 104-115 (2015-07-15)
Exposure to testosterone during a critical period of prenatal development disrupts the normal display of sexual behaviors in adult ovariectomized (OVX) rats treated with estradiol benzoate (EB) followed by progesterone (P). The organizational hypothesis posits that prenatally androgenized females (PNAFs)
Gokhan Bayramoglu et al.
Cytotechnology, 67(5), 845-849 (2014-05-09)
There is little information about the hepatoprotective effects of gallic acid against ischemia-reperfusion (I/R) damage. Animals were subjected to I/R. Gallic acid at doses of 50 and 100 mg/kg body weight (bw) were injected as a single dose prior to ischemia.
Jing Chen et al.
PLoS genetics, 10(10), e1004688-e1004688 (2014-10-31)
Spinster homolog 2 (Spns2) acts as a Sphingosine-1-phosphate (S1P) transporter in zebrafish and mice, regulating heart development and lymphocyte trafficking respectively. S1P is a biologically active lysophospholipid with multiple roles in signalling. The mechanism of action of Spns2 is still
Jing Yuan et al.
Nature chemical biology, 5(10), 765-771 (2009-09-08)
Studies of gene function and molecular mechanisms in Plasmodium falciparum are hampered by difficulties in characterizing and measuring phenotypic differences between individual parasites. We screened seven parasite lines for differences in responses to 1,279 bioactive chemicals. Hundreds of compounds were
Jong Oh Kim et al.
International journal of biological macromolecules, 79, 217-225 (2015-05-11)
Nitric oxide (NO) is a promising therapeutic agent with antibacterial and wound-healing properties. However, the gaseous state and short half-life of NO necessitate a formulation that can control its storage and release. In this study, we developed NO-releasing films (CS/NO
Pengfei Wu et al.
PloS one, 13(11), e0206131-e0206131 (2018-11-08)
Chicken is widely favored by consumers because of some unique features. The leg muscles occupy an important position in the market. However, the specific mechanism for regulating muscle growth speed is not clear. In this experiment, we used Jinghai yellow
Tomas Blanco-Mezquita et al.
Cornea, 33(11), 1225-1231 (2014-08-30)
In this study, we investigated the wound-healing process after photorefractive keratectomy with mitomycin C (MMC) in hen corneas. In addition, we evaluated the synergistic effect of ethanol and MMC. Forty-eight adult hens were divided into 3 groups: A: ethanol-assisted debridement
Lucía Ibares-Frías et al.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 253(7), 1071-1083 (2015-03-07)
To evaluate corneal wound healing in the hen animal model after additive surgery with an intracorneal ring segment (ICRS). We implanted one ICRS in each eye of 76 hens. In control group 1 (n = 22 hens), the stromal channel was prepared
Isabella M Guimaraes et al.
Molecular brain, 8, 24-24 (2015-04-18)
The metabotropic glutamate receptor 5 (mGluR5) is involved in various brain functions, including memory, cognition and motor behavior. Regarding locomotor activity, we and others have demonstrated that pharmacological antagonism of mGluR5 promotes hyperkinesia in mice. Moreover, increased locomotor activity can
Maria dos Prazeres Carneiro Cardoso et al.
Acta cirurgica brasileira, 30(2), 107-114 (2015-02-26)
To evaluate the effects of preconditioning with oils mixes containing ω3/ω6/ω9 associated with micro-currents on skin repair in rats. One-hundred and eight Wistar rats randomized into G-1, G-2 and G-3 groups were treated with saline (0.9%), mix 1 (corn+soybean oils)
Elzbieta Kolaczkowska et al.
Nature communications, 6, 6673-6673 (2015-03-27)
Neutrophil extracellular traps (NETs) composed of DNA decorated with histones and proteases trap and kill bacteria but also injure host tissue. Here we show that during a bloodstream infection with methicillin-resistant Staphylococcus aureus, the majority of bacteria are sequestered immediately
Carsten Schuldt et al.
Acta ophthalmologica, 93(5), e328-e336 (2014-12-18)
To determine the visco-elastic properties of isolated rabbit scleral tissue and dose-dependent biomechanical and morphological changes after collagen cross-linking by riboflavin/blue light treatment. Scleral patches from 87 adult albino rabbit eyes were examined by dynamic shear rheology. Scleral patches were
Keiji Ibata et al.
Neuron, 102(6), 1184-1198 (2019-05-11)
Synapse formation is achieved by various synaptic organizers. Although this process is highly regulated by neuronal activity, the underlying molecular mechanisms remain largely unclear. Here we show that Cbln1, a synaptic organizer of the C1q family, is released from lysosomes
Caroline Clouard et al.
The Journal of nutrition, 145(9), 2176-2184 (2015-07-17)
Maternal dietary docosahexaenoic acid (DHA) intake is thought to affect development in the offspring. We assessed the impact of maternal dietary DHA on behavior, brain fatty acid (FA) profile, and sickness response of offspring in pigs, a pertinent model for
Shu-I Yeh et al.
Investigative ophthalmology & visual science, 56(4), 2126-2134 (2015-02-14)
To investigate the potential of a pigment epithelial-derived factor (PEDF) peptide 44-mer to promote limbal regeneration in a rabbit partial limbal deficiency model. Limbal excision (180°) was created surgically, and topical application of 44-mer-containing ointment once a day for 2
S Gruber-Blum et al.
Hernia : the journal of hernias and abdominal wall surgery, 19(4), 651-657 (2014-09-10)
Fibrin sealant (FS) is a safe and efficient fixation method in open intraperitoneal hernia repair. While favourable results have been achieved with hydrophilic meshes, hydrophobic (such as Omega fatty acid coated) meshes (OFM) have not been specifically assessed so far.
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