CN
Search Within
Y0000016
应用筛选条件
关键词:'Y0000016'
显示 1-30 共 270 条结果 关于 "Y0000016" 范围 论文
M M Sahinovic et al.
British journal of anaesthesia, 112(1), 110-117 (2013-11-05)
The influence of frontal brain tumours on bispectral index (BIS) measurements and propofol requirements is unknown. The primary aim of our study was to determine whether BIS values recorded at loss and return of consciousness (LOC and ROC, respectively) differ
Ming-Lian Yu et al.
Die Pharmazie, 68(6), 449-452 (2013-07-24)
The present study aimed to evaluate the potential risk of drug-drug interactions associated with acitretin which is a drug for therapy of psoriasis approved by the Food and Drug Administration (FDA). The initial screening of acitretin's inhibition towards 4-methylumbelliferone (4-MU)
Jason A Campagna et al.
Anesthesiology, 121(6), 1203-1216 (2014-08-30)
Cyclopropyl-methoxycarbonyl metomidate (CPMM, also known as ABP-700) is a second-generation "soft" (i.e., metabolically labile) etomidate analogue. The purpose of this study was to characterize CPMM's pharmacology in beagle dogs in preparation for potential first in human phase 1 clinical trials.
Elif Sarıtaş Yüksel et al.
The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology, 25(3), 264-270 (2014-08-21)
To assess the sensitivity of magnetic resonance enterography (MRE) in the diagnosis of Crohn's disease (CD) activity and correlation between endoscopic and MRE scores in predicting the activity grade. Twenty-five ileal CD patients with clinical and biochemical evidence of activation
Arslan Onuk Asuman et al.
Middle East journal of anaesthesiology, 22(1), 47-52 (2013-07-10)
The aim of the study was to examine intraocular pressure (IOP) changes during laparoscopic cholecystectomy performed under either desflurane-thiopental anesthesia or propofol total intravenous anesthesia (TIVA). 36 patients who will undergo elective laparoscopic cholecystectomy were enrolled in the study. The
The slow death of lethal injection.
Owen Dyer
BMJ (Clinical research ed.), 348, g2670-g2670 (2014-05-02)
Jianhua Chang et al.
Experimental and molecular pathology, 112, 104327-104327 (2019-11-05)
Hypoxia was proven to cause brain cell apoptosis and autophagy. Herein, we tested the influences of propofol, a commonly used intravenous sedative hypnotic drug, on apoptosis and autophagy aroused by hypoxia stimulation in PC-12 and HT-22 cells. Followed by hypoxia
K Kaskinoro et al.
Anaesthesia, 70(2), 190-204 (2014-10-01)
Although electroencephalogram reactivity (i.e. transient changes in electrical brain activity following external stimulus) might be useful in depth-of-anaesthesia monitoring, it has not been systematically examined with different anaesthetics at doses titrated to unresponsiveness. Three 10-subject groups of healthy volunteers received
Tao Yu et al.
The Journal of surgical research, 193(2), 849-855 (2014-10-01)
Predicting fluid responsiveness is crucial for fluid administration in septic shock patients. Midazolam and propofol decrease vascular tone and venous return, which may influence preload dependency. However, little is known about the effects of these two sedatives on preload dependency
Cardiac output decrease and propofol: what is the mechanism?
David W Green
British journal of anaesthesia, 114(1), 163-164 (2014-12-17)
Letter by Zaugg and Lucchinetti regarding article, "Randomized comparison of sevoflurane versus propofol to reduce perioperative myocardial ischemia in patients undergoing noncardiac surgery".
Michael Zaugg et al.
Circulation, 127(25), e875-e875 (2013-06-26)
A J Thomson et al.
Anaesthesia, 69(5), 420-428 (2014-04-18)
Debate continues over the most appropriate blood-brain equilibration rate constant (ke0) for use with the Marsh pharmacokinetic model for propofol. We aimed to define the optimal ke0 value. Sixty-four patients were sedated with incremental increases in effect-site target concentration of
M V Madsen et al.
Acta anaesthesiologica Scandinavica, 59(4), 441-447 (2015-03-20)
Insufflation of the abdomen during laparoscopy improves surgical space, but may cause post-operative shoulder pain. The incidence of shoulder pain is reduced using a lower insufflation pressure, but this may, however, compromise the surgical space. We aimed at investigating whether
Brian P Weiser et al.
Scientific reports, 5, 9695-9695 (2015-04-09)
We used a photoactive general anesthetic called meta-azi-propofol (AziPm) to test the selectivity and specificity of alkylphenol anesthetic binding in mammalian brain. Photolabeling of rat brain sections with [(3)H]AziPm revealed widespread but heterogeneous ligand distribution, with [(3)H]AziPm preferentially binding to
Kohei Yamamoto et al.
European journal of drug metabolism and pharmacokinetics, 39(3), 195-202 (2014-01-29)
UDP-glucuronosyltransferase 1A9 (UGT1A9) contributes to the glucuronidation of numerous drugs. Cynomolgus monkeys are regarded as experimental animals similar to humans in studies on safety evaluation and biotransformation for drug development. In this study, the similarities and differences in the enzymatic
Muhammad Suleman Khan et al.
Basic & clinical pharmacology & toxicology, 115(6), 565-570 (2014-06-04)
A variety of techniques have been developed to monitor the depth of anaesthesia. Propofol's pharmacokinetics and response vary greatly, which might be explained by genetic polymorphisms. We investigated the impact of genetic variations on dosage, anaesthetic depth and recovery after
Zakaria Messieha
Anesthesia progress, 60(2), 67-71 (2013-06-15)
Emergence delirium and agitation (EAD) associated with sevoflurane general anesthesia are very commonly observed in young children. Such events pose a risk for injury as well as decreased parental satisfaction, especially in the ambulatory and office-based setting. This article reviews
Zaiqi Yang et al.
Molecular medicine reports, 11(1), 589-596 (2014-10-18)
The present study aimed to identify changes in atrial gene expression induced by sevoflurane and propofol using DNA microarray. The expression profiles of GSE4386 in atrial samples, obtained from patients who had received either the anesthetic gas sevoflurane or the
Ruei-Ming Chen et al.
Surgery, 154(1), 58-68 (2013-05-21)
Cerebrovascular endothelial cells (CECs), major component cells of the blood-brain barrier, can be injured by oxidative stress. Propofol can protect cells from oxidative injury. The aim of this study was to evaluate the effects of propofol on nitrosative stress-induced insults
Takayuki Kunisawa et al.
Therapeutics and clinical risk management, 11, 107-114 (2015-02-06)
We previously determined the pharmacokinetic (PK) parameters of landiolol in healthy male volunteers and gynecological patients. In this study, we determined the PK parameters of landiolol in patients with peripheral arterial disease. Eight patients scheduled to undergo peripheral arterial surgery
UnCheol Lee et al.
Anesthesiology, 118(6), 1264-1275 (2013-05-23)
Directional connectivity from anterior to posterior brain regions (or "feedback" connectivity) has been shown to be inhibited by propofol and sevoflurane. In this study the authors tested the hypothesis that ketamine would also inhibit cortical feedback connectivity in frontoparietal networks.
Primum non nocere or how to resolve drug-induced respiratory depression.
Albert Dahan et al.
Anesthesiology, 118(6), 1261-1263 (2013-05-24)
Akira Asai et al.
Internal medicine (Tokyo, Japan), 52(7), 761-765 (2013-04-03)
A 75-year-old woman developed depression in 2010 and was treated with oral medications at our Department of Psychiatry. Since she showed no tendency toward improvement, she underwent modified electroconvulsive therapy (mECT). Later, she developed severe liver injury that was presumably
Improving safety during sedation by nonanesthesiologists: do we lead or follow?
Carl Rosow
Anesthesia and analgesia, 119(1), 7-8 (2014-06-20)
Miki Iida et al.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 33(6), 1827-1837 (2014-06-28)
Intravenous anesthetics are used during the perioperative and/or postoperative period in critically ill patients. Vascular smooth muscle cells (VSMCs) play important roles in vascular injury repair or restenosis after intervention. We previously reported that platelet-derived growth factor (PDGF)-BB induces VSMC
So-Hyun Jansen-Park et al.
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 46(3), 356-360 (2014-02-07)
Real-time monitoring of the aortic valve function and the loading state of the left ventricle (LV) during mechanical circulatory support is essential. Therefore, we developed a system that determines accurately the aortic valve closing moment based on integrals derived from
Justin A R Lang et al.
Journal of applied physiology (Bethesda, Md. : 1985), 117(5), 535-543 (2014-07-06)
At birth, the transition to newborn life is triggered by lung aeration, which stimulates a large increase in pulmonary blood flow (PBF). Current theories predict that the increase in PBF is spatially related to ventilated lung regions as they aerate
Lisa Rancan et al.
Transplantation, 98(11), 1151-1157 (2014-10-01)
Transplants cause ischemia-reperfusion (IR) injury that can affect distant organs. Liver is particularly sensitive to IR injury. The present randomized experimental study was designed to investigate a possible protective effect of sevoflurane against liver inflammatory response to lung IR in
Thoracic epidural anesthesia in abdominal aortic surgery: use and advantages.
Miguel Angel Palomero Rodríguez et al.
Anesthesiology, 120(5), 1288-1289 (2014-04-24)
Christoph Haller et al.
Nucleic acid therapeutics, 25(1), 20-26 (2014-12-11)
A multitude of stem cell types has been extensively studied and used for myocardial regenerative therapy. Amongst these endothelial progenitor cells form a promising source. In our present study, we investigated a one-staged approach for isolation and application of autologous
1/9