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显示 1-30 #N/A 810 条结果 关于 "Y0000796" 范围 论文
Maria Spiliotaki et al.
Breast cancer research : BCR, 16(6), 485-485 (2014-11-30)
Clinical dormancy is frequently observed in breast cancer. In the present study, we aimed to characterize circulating tumor cells (CTCs) in dormancy candidates (DC) with early breast cancer in terms of proliferation and apoptosis. Cytospins of peripheral blood mononuclear cells
Tongyu Liu et al.
Journal of neuroscience research, 92(9), 1199-1204 (2014-05-09)
Ependymal cells are multiciliated epithelial cells that line the ventricles in the adult brain. Abnormal function or structure of ependymal cilia has been associated with various neurological deficits. For the first time, we report three distinct ependymal cell types, I
Ji-Young Na et al.
Research in veterinary science, 97(3), 605-610 (2014-12-04)
This study evaluated the effectiveness of irradiated porcine tendon xenografts for lateral collateral ligament (LCL) reconstruction. Twenty healthy adult beagle dogs underwent LCL reconstruction using irradiated porcine tendons treated with poly-gamma-glutamic acid. Serological and histological assessments were performed to evaluate
Jogchum Plat et al.
PloS one, 9(10), e110758-e110758 (2014-10-31)
The inflammatory component of non-alcoholic steatohepatitis (NASH) can lead to irreversible liver damage. Therefore there is an urgent need to identify novel interventions to combat hepatic inflammation. In mice, omitting cholesterol from the diet reduced hepatic inflammation. Considering the effects
Qingli Zhang et al.
The Journal of general virology, 95(Pt 12), 2700-2709 (2014-09-11)
A new nodavirus, named covert mortality nodavirus (CMNV), is associated with covert mortality disease of shrimp which has caused serious loss in China since 2009. Histopathological examination of shrimp suffering the disease revealed coagulative necrosis of striated muscle similar to
Xiangjun Kong et al.
Colloids and surfaces. B, Biointerfaces, 122, 359-367 (2014-08-02)
By using 2-N,6-O-sulfated chitosan (26SCS) immobilized poly(lactide-co-glycolide) (PLGA) scaffolds, our system achieved controlled release and improved bioactivity of recombinant human bone morphology protein-2 (rhBMP-2). Initially aminolyzed by ethylenediamine, PLGA scaffolds surface was immobilized with 26SCS via electrostatic assembly. Upon the
You Wu et al.
Journal of applied physiology (Bethesda, Md. : 1985), 117(7), 788-796 (2014-08-02)
With proteinaceous-liquid flooding of discrete alveoli, a model of the edema pattern in the acute respiratory distress syndrome, lung inflation over expands aerated alveoli adjacent to flooded alveoli. Theoretical considerations suggest that the overexpansion may be proportional to surface tension
Yukio Akasaki et al.
Arthritis & rheumatology (Hoboken, N.J.), 66(12), 3349-3358 (2014-09-05)
A major signaling pathway that regulates cellular aging is the insulin/insulin-like growth factor 1 (IGF-1)/phosphatidylinositol 3-kinase (PI3K)/Akt/FoxO transcription factor axis. We previously observed that FoxO transcription factors are dysregulated in aged and OA cartilage. The objective of this study was
Jiansuo Zhou et al.
Molecular medicine reports, 10(2), 971-976 (2014-05-21)
This study investigated the role of microRNA-21 (miR-21) and microRNA-24 (miR-24) in the pathological processes that follow cerebral ischemic injury and examined the potential use of miR-21 and -24 in stroke diagnostics as sensitive plasma biomarkers. An oxygen-glucose deprivation (OGD)
Konrad Kleszczyński et al.
Journal of pineal research, 58(1), 117-126 (2014-11-27)
Melatonin, a lipophilic compound synthesized and released from the pineal gland, effectively acts against ultraviolet radiation (UVR), one of the main inducers of epidermal damage, skin cancer, inflammation, and DNA photo damage. One of the common known stress protein induced
Rafael Ramos Caiado et al.
Arquivos brasileiros de oftalmologia, 77(5), 288-292 (2014-12-11)
Purpose: To compare intraocular pressure (IOP) using the simplified daily tensional curve (SDTC) between supine and sitting positions in terms of peak levels and amount of fluctuation in both, glaucomatous and healthy subjects. The secondary endpoint was the comparison of
Carl Weitlauf et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 34(46), 15369-15381 (2014-11-14)
Progression of neurodegeneration in disease and injury is influenced by the response of individual neurons to stressful stimuli and whether this response includes mechanisms to counter declining function. Transient receptor potential (TRP) cation channels transduce a variety of disease-relevant stimuli
G R Willis et al.
BJOG : an international journal of obstetrics and gynaecology, 121(13), 1596-1603 (2014-05-13)
To assess circulating biochemical indices of endothelial function and nitro-oxidative stress in women with polycystic ovary syndrome (PCOS). Case-control study. Seventeen women with PCOS and eighteen age- and body mass index-matched healthy volunteers. Nitric oxide (NO) metabolite levels were assessed
Tyson J Smyth et al.
Biochimica et biophysica acta, 1838(11), 2954-2965 (2014-08-08)
Small endogenous vesicles called exosomes are beginning to be explored as drug delivery vehicles. The in vivo targets of exosomes are poorly understood; however, they are believed to be important in cell-to-cell communication and may play a prominent role in
Kyle D Dukes et al.
Analytical biochemistry, 458, 43-48 (2014-04-24)
Silver nanoparticles have been modified with self-assembled monolayers of hydroxyl-terminated long chain thiols and encapsulated with a silica shell. The resulting core-shell nanoparticles were used as optical labels for cell analysis using flow cytometry and microscopy. The excitation of plasmon
Toshio Hisatomi et al.
Retina (Philadelphia, Pa.), 35(2), 310-318 (2014-08-12)
Brilliant Blue G is used as a surgical adjuvant for retinal surgery. Although BBG double or multiple staining was reported, the effectiveness and safety of repeated staining is still elusive. To further examine the effectiveness and safety, we examined BBG
Donato Citarella et al.
Journal of contaminant hydrology, 172, 10-23 (2014-12-03)
This paper describes the application of an innovative procedure that allows the estimation of longitudinal and transverse dispersivities in an experimental plume devised in a laboratory sandbox. The phenomenon of transport in porous media is studied using sodium fluorescein as
Chi-Cheng Lu et al.
Oncology reports, 32(2), 597-606 (2014-06-13)
The aim of the present study was to explore the effect of 6-fluoro-2-(3-fluorophenyl)-4-(cyanoanilino) quinazoline (HMJ-30) on the anti-angiogenic properties and apoptosis-related mechanism of human umbilical vein endothelial cells (HUVECs). In this study, HMJ-30 dose- and time-dependently inhibited the viability of
Long Wang et al.
Molecular medicine reports, 11(4), 2711-2716 (2014-12-18)
Glucocorticoid‑induced osteoporosis (GIOP) is a widespread clinical complication following glucocorticoid therapy. This irreversible damage to bone‑forming and ‑resorbing cells is essential in the pathogenesis of osteoporosis. Autophagy is a physiological process involved in the regulation of cells and their responses
Jessica MacIntyre et al.
European journal of pharmacology, 735, 105-114 (2014-04-23)
The endocannabinoid system plays a role in regulation of vasoactivity in the peripheral vasculature; however, little is known about its role in regulation of the CNS microvasculature. This study investigated the pharmacology of cannabinoids and cannabimimetic lipids in the retinal
Kenzo Sonoda et al.
BioMed research international, 2014, 482396-482396 (2014-09-02)
In several human malignancies, the expression of receptor-binding cancer antigen expressed on SiSo cells (RCAS1) is associated with aggressive characteristics and poor overall survival. RCAS1 alters the tumor microenvironment by inducing peripheral lymphocyte apoptosis and angiogenesis, while reducing the vimentin-positive
Hua Liang et al.
Medical oncology (Northwood, London, England), 32(5), 151-151 (2015-04-04)
Platelets play an important role in metastasis of circulating tumor cells (CTCs). It has been demonstrated that hydroxyethyl starch (HES) inhibits platelets function. However, the effect of HES on CTCs in patients with colorectal cancer remains unclear. We compared the
Shinya Takahashi et al.
Frontiers in plant science, 6, 254-254 (2015-05-09)
Ultraviolet (UV)-B irradiation leads to DNA damage, cell cycle arrest, growth inhibition, and cell death. To evaluate the UV-B stress-induced changes in plant cells, we developed a model system based on tobacco Bright Yellow-2 (BY-2) cells. Both low-dose UV-B (low
[Fluorescence properties and metabolic features of fluorescein].
T Desmettre et al.
Journal francais d'ophtalmologie, 23(9), 821-833 (2001-02-24)
Liang Zhou et al.
Oncology reports, 32(4), 1734-1740 (2014-08-12)
As a highly aggressive malignant disease, the prognosis of patients with pancreatic ductal adenocarcinoma (PDAC) is poor. Yet, the mechanisms underlying the progression of PDAC remain unclear. MicroRNAs (miRNAs) may be involved in various human cancers as cancer suppressors or
Thomas Buus Jensen et al.
PloS one, 10(4), e0124902-e0124902 (2015-04-16)
Albumin has been identified in preparations of renal distal tubules and collecting ducts by mass spectrometry. This study aimed to establish whether albumin was a contaminant in those studies or actually present in the tubular cells, and if so, identify
B Li et al.
Free radical research, 48(7), 758-768 (2014-04-12)
Stromal interaction molecule (STIM) proteins are parts of elaborate eukaryotic Ca(2+) signaling systems and are considered to be important players in regulating neuronal Ca(2+) homeostasis under normal ageing and pathological conditions. Here, we investigated the potential role of STIM1 in
Yuan Gao et al.
International journal of molecular sciences, 15(11), 20982-20996 (2014-11-19)
The aim of this study was to isolate human mesenchymal stem cells (MSCs) from the gingiva (GMSCs) and confirm their multiple differentiation potentials, including the odontogenic lineage. GMSCs, periodontal ligament stem cells (PDLSCs) and dermal stem cells (DSCs) cultures were
Eiichi Hasegawa et al.
PloS one, 9(9), e106507-e106507 (2014-09-05)
Vision loss due to vascular disease of the retina is a leading cause of blindness in the world. Retinal angiomatous proliferation (RAP) is a subgroup of neovascular age-related macular degeneration (AMD), whereby abnormal blood vessels develop in the retina leading
Cindy X Guo et al.
Molecular vision, 20, 670-682 (2014-06-03)
Changes in connexin expression are associated with many pathological conditions seen in animal models and in humans. We hypothesized that gap junctions are important mediators in tissue dysfunction and injury processes in the retina, and therefore, we investigated the pattern
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