Merck
CN

A protocol for the management of adhesive small bowel obstruction.

The journal of trauma and acute care surgery (2014-12-30)
Tyler Loftus, Frederick Moore, Erin VanZant, Trina Bala, Scott Brakenridge, Chasen Croft, Lawrence Lottenberg, Winston Richards, David Mozingo, Linda Atteberry, Alicia Mohr, Janeen Jordan
摘要

Differentiating between partial adhesive small bowel obstruction (aSBO) likely to resolve with medical management and complete obstruction requiring operative intervention remains elusive. We implemented a standardized protocol for the management of aSBO and reviewed our experience retrospectively. Patients with symptoms of aSBO were admitted for intravenous fluid resuscitation, bowel rest, nasogastric tube decompression, and abdominal examinations every 4 hours. Laboratory values and a computed tomography scan of the abdomen and pelvis with intravenous contrast were obtained. Patients with peritonitis or computed tomography scan findings suggesting bowel compromise were taken to the operating room for exploration following resuscitation. All other patients received 80 mL of Gastroview (GV) and 40 mL of sterile water via nasogastric tube. Abdominal plain films were obtained at 4, 8, 12, and 24 hours. If contrast did not reach the colon within 24 hours, then operative intervention was performed. Over 1 year, 91 patients were admitted with aSBO. Sixty-three patients received GV, of whom 51% underwent surgery. Twenty-four patients went directly to the operating room because of clinical or imaging findings suggesting bowel ischemia. Average time to surgery was within 1 day for the no-GV group and 2 days for the GV group. Patients passing GV to the colon within 5 hours of administration had a 90% rate of resolution of obstruction. There was a direct relationship between the duration of time before passing GV to the colon and hospital length of stay (HLOS) (r = 0.459). Patients who received GV and did not require surgery had lower HLOS (3 days vs. 11 days, p < 0.0001). The GV protocol facilitated early recognition of complete obstruction. Administration of GV had diagnostic and therapeutic value and did not increase HLOS, morbidity, or mortality. Therapeutic study, level V. Epidemiologic study, level V.

材料
货号
品牌
产品描述

Sigma-Aldrich
碳酸氢钠, powder, BioReagent, for molecular biology, suitable for cell culture, suitable for insect cell culture
Sigma-Aldrich
碳酸氢钠, ACS reagent, ≥99.7%
Sigma-Aldrich
碳酸氢钠 溶液, solution (7.5%), sterile-filtered, BioReagent, suitable for cell culture
Sigma-Aldrich
碳酸氢钠, ReagentPlus®, ≥99.5%, powder
Sigma-Aldrich
碳酸氢钠, BioXtra, 99.5-100.5%
Sigma-Aldrich
碳酸氢钠, puriss., meets analytical specification of Ph. Eur., BP, USP, FCC, E500, 99.0-100.5%, powder
Supelco
碳酸氢钠溶液, 0.1 M NaHCO3 in water, eluent concentrate for IC
USP
碳酸氢钠, United States Pharmacopeia (USP) Reference Standard
Sigma-Aldrich
碳酸氢钠, tested according to Ph. Eur.
Sigma-Aldrich
碳酸氢钠, anhydrous, free-flowing, Redi-Dri, ReagentPlus®, ≥99.5%
Sigma-Aldrich
碳酸氢钠, −40-+140 mesh, ≥95%
Sigma-Aldrich
重碳酸钠-12C, 99.9 atom % 12C
Sigma-Aldrich
碳酸氢钠, Vetec, reagent grade, 99%