CN
APP
amyloid beta (A4) precursor protein
别名:
AAA, ABETA, ABPP, AD1, APPI, CTFgamma, CVAP, PN-II, PN2
物种:
Human APP (351), Mouse App (11820), Rat App (54226), fruit fly app (39399), chicken APP (374198), dog APP (403407), domestic cat APP (101085564), cow APP (280722), sheep APP (101111593), domestic guinea pig App (100715302)
UniProtKB ID:
基因ID:
- Human(351) Summary: This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- Mouse(11820) amyloid beta (A4) precursor protein
- Rat(54226) amyloid beta (A4) precursor protein
- fruit fly(39399) approximated
- chicken(374198) amyloid beta (A4) precursor protein
- dog(403407) amyloid beta (A4) precursor protein
- domestic cat(101085564) amyloid beta (A4) precursor protein
- cow(280722) amyloid beta (A4) precursor protein
- sheep(101111593) amyloid beta (A4) precursor protein
- domestic guinea pig(100715302) amyloid beta (A4) precursor protein
- naked mole-rat(101724743) amyloid beta (A4) precursor protein
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ELISA
货号
说明
物种
Human Amyloid β42 Brain ELISA, This Human Amyloid β42 Brain ELISA is used to measure & quantify Amyloid β42 levels in Neuroscience research.,
物种
human
High Sensitivity Human Amyloid β40 ELISA, This High Sensitivity Human Amyloid β40 ELISA is used to measure & quantify Amyloid β40 levels in Neuroscience research.,
物种
human
High Sensitivity Human Amyloid β42 ELISA, This High Sensitivity Human Amyloid β42 ELISA is used to measure & quantify Amyloid β42 levels in Neuroscience research.,
物种
human
Small Molecule - Antagonist
Antibodies
货号
说明
物种反应性
应用
抗APP A4抗体，a.a.APP{NT}的66-81，克隆22C11, clone 22C11, Chemicon®, from mouse,
物种反应性
canine, fish, human, monkey, mouse, pig, rat
应用
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
抗β-淀粉样蛋白1-42抗体, Chemicon®, from rabbit,
物种反应性
chicken, human, mouse
应用
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
抗淀粉样蛋白抗体，β1-40, Chemicon®, from rabbit,
物种反应性
human, mouse
应用
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
抗-APP-C99抗体，克隆mC99（70–80）, ascites fluid, clone mC99(70-80), from mouse,
物种反应性
human, mouse
应用
immunofluorescence
immunohistochemistry
immunoprecipitation (IP)
western blot
immunohistochemistry
immunoprecipitation (IP)
western blot
抗淀粉样蛋白寡聚体抗体，αβ，寡聚体, serum, Chemicon®,
物种反应性
eukaryotes, human, mouse, rat
应用
ELISA
immunofluorescence
immunohistochemistry
immunoprecipitation (IP)
western blot
immunofluorescence
immunohistochemistry
immunoprecipitation (IP)
western blot