Merck
CN

CHRNA3

cholinergic receptor, nicotinic, alpha 3 (neuronal)

别名:
LNCR2, NACHRA3, PAOD2
物种:
UniProtKB ID:
基因ID:
  • Human(1136) Summary: This locus encodes a member of the nicotinic acetylcholine receptor family of proteins. Members of this family of proteins form pentameric complexes comprised of both alpha and beta subunits. This locus encodes an alpha-type subunit, as it contains characteristic adjacent cysteine residues. The encoded protein is a ligand-gated ion channel that likely plays a role in neurotransmission. Polymorphisms in this gene have been associated with an increased risk of smoking initiation and an increased susceptibility to lung cancer. Alternatively spliced transcript variants have been described. [provided by RefSeq, Nov 2009]
  • Mouse(110834) cholinergic receptor, nicotinic, alpha polypeptide 3
  • Rat(25101) cholinergic receptor, nicotinic, alpha 3 (neuronal)
  • domestic guinea pig(100730977) cholinergic receptor, nicotinic, alpha 3 (neuronal)
  • naked mole-rat(101701279) cholinergic receptor, nicotinic, alpha 3 (neuronal)
  • sheep(101123239) cholinergic receptor, nicotinic, alpha 3 (neuronal)
  • Domestic Rabbit(100342666) cholinergic receptor, nicotinic, alpha 3 (neuronal)
  • dog(482111) cholinergic receptor, nicotinic, alpha 3 (neuronal)
  • cow(282702) cholinergic receptor, nicotinic, alpha 3 (neuronal)
  • domestic cat(100037403) cholinergic receptor, nicotinic, alpha 3 (neuronal)
  • Zebrafish(568467) cholinergic receptor, nicotinic, alpha 3
  • chicken(386578) cholinergic receptor, nicotinic, alpha 3

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Small Molecule - Agonist

货号
说明
物种
卡巴胆碱, ≥98% (titration), crystalline,
物种
human, mouse, rat
十烃溴铵, crystalline,
物种
human
1,1-二甲基-4-苯基哌嗪碘化物, ≥98% (TLC or titration),
物种
human, rat

Small Molecule - Antagonist

货号
说明
物种
卡巴胆碱, ≥98% (titration), crystalline,
物种
human, mouse, rat
美加明 盐酸盐, ,
物种
human
1,1-二甲基-4-苯基哌嗪碘化物, ≥98% (TLC or titration),
物种
human, rat
犬尿喹啉酸, ≥98%,
物种
rat, human

Antibodies

货号
说明
物种反应性
应用
Anti-CHRNA3 antibody produced in rabbit, affinity isolated antibody,
物种反应性
dog, human, rabbit
应用
western blot
Monoclonal Anti-Nicotinic Acetylcholine Receptor (α1, α3, α5 Subunits) antibody produced in rat, clone mAb 35, purified immunoglobulin, buffered aqueous solution,
物种反应性
chicken, eel, human
应用
immunohistochemistry

Small Molecule - Blocker

货号
说明
物种
四乙基氯化铵, ≥98% (titration),
物种
human
溴化已烷双胺, ,
物种
human
氯化六甲铵, solid (hygroscopic),
物种
human
犬尿喹啉酸, ≥98%,
物种
rat, human

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting human CHRNA3,
物种
human
MISSION® esiRNA, targeting mouse Chrna3,
物种
mouse