Merck
CN

CYP19A1

cytochrome P450, family 19, subfamily A, polypeptide 1

别名:
ARO, ARO1, CPV1, CYAR, CYP19, CYPXIX, P-450AROM
物种:
Human CYP19A1 (1588), Mouse Cyp19a1 (13075), Rat Cyp19a1 (25147), Goat CYP19A1 (100861413), Horse CYP19A1 (100009712), dog CYP19A1 (494003), chicken CYP19A1 (414854), Domestic Rabbit CYP19A1 (100328545), cow CYP19A1 (281740)
UniProtKB ID:
P11511, Q16731, Q3B764, Q58FA0
基因ID:
  • Human(1588) Summary: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and catalyzes the last steps of estrogen biosynthesis, three successive hydroxylations of the A ring of androgens. Mutations in this gene can result in either increased or decreased aromatase activity; the associated phenotypes suggest that estrogen functions both as a sex steroid hormone and in growth or differentiation. The gene expresses two transcript variants. [provided by RefSeq, Jul 2008]
  • Mouse(13075) cytochrome P450, family 19, subfamily a, polypeptide 1
  • Rat(25147) cytochrome P450, family 19, subfamily a, polypeptide 1
  • Goat(100861413) cytochrome P450, family 19, subfamily A, polypeptide 1
  • Horse(100009712) cytochrome P450, family 19, subfamily A, polypeptide 1
  • dog(494003) cytochrome P450, family 17, subfamily A, polypeptide 1
  • chicken(414854) cytochrome P450, family 19, subfamily A, polypeptide 1
  • Domestic Rabbit(100328545) cytochrome P450, family 19, subfamily A, polypeptide 1
  • cow(281740) cytochrome P450, family 19, subfamily A, polypeptide 1

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Antibodies

货号
说明
物种反应性
应用
SAB4500606
Anti-Cytochrome P450 19A1 antibody produced in rabbit, affinity isolated antibody,
物种反应性
human, mouse, rat
应用
ELISA
immunofluorescence
immunohistochemistry
western blot
HPA051194
抗-CYP19A1 兔抗, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunofluorescence
immunohistochemistry
ABN30
Anti-Aromatase Antibody, from rabbit, purified by affinity chromatography,
物种反应性
bovine, canine, chimpanzee, human, pig, porcine, rhesus macaque
应用
western blot
SAB5702040
Anti-Aromatase (CYP19A1) Antibody, clone 5C5N7, Rabbit Monoclonal, ,
物种反应性
human
应用
immunofluorescence
immunohistochemistry
western blot
SAB1410280
Anti-CYP19A1 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
western blot

Cell Lines

货号
说明
物种
MTOXCE19A1
CypExpress™ 芳香酶, ,
物种
human

Small Molecule - Inhibitor

货号
说明
物种
L6545
来曲唑, ≥98% (HPLC),
物种
human
PHR1540
来曲唑, Pharmaceutical Secondary Standard; Certified Reference Material,
物种
human
BP1234
来曲唑, British Pharmacopoeia (BP) Reference Standard,
物种
human
545872
(R)-(+)-氨鲁米特, 97%,
物种
human
D2016
鹰嘴豆芽素A, ,
物种
human, mouse

esiRNA

货号
说明
物种
EHU036781
MISSION® esiRNA, targeting human CYP19A1,
物种
human
EMU044241
MISSION® esiRNA, targeting mouse Cyp19a1,
物种
mouse