Merck
CN

EGFR

epidermal growth factor receptor

别名:
ERBB, ERBB1, HER1, PIG61, mENA
物种:
UniProtKB ID:
基因ID:
  • Human(1956) Summary: The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. Multiple alternatively spliced transcript variants that encode different protein isoforms have been found for this gene. [provided by RefSeq, Jul 2010]
  • Mouse(13649) epidermal growth factor receptor
  • Rat(24329) epidermal growth factor receptor
  • sheep(780479) epidermal growth factor receptor
  • domestic guinea pig(100725363) epidermal growth factor receptor
  • dog(404306) epidermal growth factor receptor
  • fruit fly(37455) Epidermal growth factor receptor
  • Horse(100067755) epidermal growth factor receptor
  • cow(407217) epidermal growth factor receptor
  • naked mole-rat(101723771) epidermal growth factor receptor
  • domestic cat(100510799) epidermal growth factor receptor
  • chicken(396494) epidermal growth factor receptor

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ELISA

货号
说明
物种
磷酸化EGFR(pSer 1070)ELISA试剂盒, for detection of human, mouse or rat phospho-egfr (pSer1070) in cell and tissue lysates,
物种
human
磷酸化EGFR(pTyr1045)和pan-EGFR ELISA试剂盒, for detection of human phospho-egfr (pTyr1045) and pan-egfr in cell and tissue lysates,
物种
human
磷酸化EGFR (pTyr1086)和pan-EGFR ELISA试剂盒, for detection of human phospho-egfr (pTyr1086) and pan-egfr in cell and tissue lysates,
物种
human
检测培养细胞系中磷酸化EGFR (pTyr845)的基于细胞的ELISA 试剂盒, 96 assays,
物种
human
磷酸化EGFR (pTyr1086) ELISA 试剂盒, for detection of human phospho-egfr (pTyr1086) in cell and tissue lysates,
物种
human

Small Molecule - Antagonist

货号
说明
物种
Tyrphostin AG 1478(酪氨酸激酶抑制剂AG 1478), ≥98%,
物种
human, mouse
SU 5416, ≥98% (HPLC),
物种
human, mouse
染料木黄酮, synthetic, ≥98% (HPLC), powder,
物种
mouse, human, rat
染料木黄酮, from Glycine max (soybean), ~98% (HPLC),
物种
mouse, human, rat

Antibodies

货号
说明
物种反应性
应用
Anti-EGFR antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human, mouse, rat
应用
immunofluorescence
immunohistochemistry

western blot
Anti-EGFRvIII Antibody, clone DH8.3, clone DH8.3, from mouse,
物种反应性
human
应用
ELISA
flow cytometry

immunohistochemistry

immunoprecipitation (IP)

western blot
Anti-EGFR antibody produced in rabbit, Ab1, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry
Anti-EGFR Antibody, clone LA22, clone LA22, Upstate®, from mouse,
物种反应性
human
应用
immunocytochemistry
immunoprecipitation (IP)

western blot
抗-EGFR抗体,中和,克隆LA1, clone LA1, Upstate®, from mouse,
物种反应性
human
应用
immunocytochemistry
immunohistochemistry

immunoprecipitation (IP)

neutralization

western blot

Small Molecule - Inhibitor

货号
说明
物种
吉非替尼, ≥98% (HPLC),
物种
human
吉非替尼, European Pharmacopoeia (EP) Reference Standard,
物种
human
Tyrphostin 1, ≥98%,
物种
human
PKI-166, ≥98% (HPLC),
物种
human
厄洛替尼盐酸盐, ,
物种
human

Proteins

货号
说明
物种
EGFR (T790M L858R) Active human, recombinant, expressed in baculovirus infected insect cells, ≥70% (SDS-PAGE),
物种
human
EGFR/ErbB1 human, recombinant, expressed in HEK 293 cells, ≥95% (SDS-PAGE),
物种
human
EGFR (T790M C797S L858R), Active, PRECISIO ®Kinase, recombinant,
物种
human
EGFR (L861Q), active, GST tagged human, PRECISIO®, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
物种
human
EGFR (D746-750 C797S), Active, recombinant,
物种
human

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting human EGFR,
物种
human
MISSION® esiRNA, targeting mouse Egfr,
物种
mouse