Merck
CN

HRH3

histamine receptor H3

Synonyms:
GPCR97, HH3R
Species:
Human HRH3 (11255), Mouse Hrh3 (99296), Rat Hrh3 (85268), sheep HRH3 (101121700), Domestic Rabbit HRH3 (100009035), chicken HRH3 (428147), dog HRH3 (477282), domestic cat HRH3 (101084437), cow HRH3 (789851), Zebrafish hrh3 (561773)
UniProtKB ID:
Q9Y5N1, Q4QRI7, Q9GZX2, Q9H4K8
Gene ID:
  • Human(11255) Summary: Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by histamine receptors H1, H2, H3 and H4. This gene encodes one of the histamine receptors (H3) which belongs to the family 1 of G protein-coupled receptors. It is an integral membrane protein and can regulate neurotransmitter release. This receptor can also increase voltage-dependent calcium current in smooth muscles and innervates the blood vessels and the heart in cardiovascular system. [provided by RefSeq, Jul 2008]
  • Mouse(99296) histamine receptor H3
  • Rat(85268) histamine receptor H3
  • sheep(101121700) histamine receptor H3
  • Domestic Rabbit(100009035) histamine receptor H3
  • chicken(428147) histamine receptor H3
  • dog(477282) histamine receptor H3
  • domestic cat(101084437) histamine receptor H3
  • cow(789851) histamine receptor H3
  • Zebrafish(561773) histamine receptor H3
  • domestic guinea pig(100135541) histamine receptor H3

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Small Molecule - Agonist

Product Number
Description
Species
I135
Imetit dihydrobromide, ≥98% (HPLC),
Species
human
H128
(R)(−)-α-Methylhistamine dihydrochloride, solid, ≥98% (HPLC),
Species
human
1065618
Betahistine hydrochloride, United States Pharmacopeia (USP) Reference Standard,
Species
human
PHR2097
Betahistine Hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material,
Species
human
Y0000391
Betahistine dihydrochloride, European Pharmacopoeia (EP) Reference Standard,
Species
human

Small Molecule - Antagonist

Product Number
Description
Species
T123
Thioperamide maleate salt, solid,
Species
human
1065618
Betahistine hydrochloride, United States Pharmacopeia (USP) Reference Standard,
Species
human
PHR2097
Betahistine Hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material,
Species
human
Y0000391
Betahistine dihydrochloride, European Pharmacopoeia (EP) Reference Standard,
Species
human
B4638
Betahistine dihydrochloride, ≥98%,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
SAB5701457
Anti-HRH3 antibody produced in rabbit, ,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot

Small Molecule - Inhibitor

Product Number
Description
Species
H7125
Histamine, ≥97.0%,
Species
human, rat

Small Molecule - Metabolite

Product Number
Description
Species
M4910
1-Methylhistamine dihydrochloride, ≥98% (TLC), powder,
Species
human

esiRNA

Product Number
Description
Species
EHU141391
MISSION® esiRNA, targeting human HRH3,
Species
human