Merck
CN

KCNA2

potassium voltage-gated channel, shaker-related subfamily, member 2

别名:
HBK5, HK4, HUKIV, KV1.2, MK2, NGK1, RBK2
物种:
UniProtKB ID:
基因ID:
  • Human(3737) Summary: Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It belongs to the delayed rectifier class, members of which allow nerve cells to efficiently repolarize following an action potential. The coding region of this gene is intronless, and the gene is clustered with genes KCNA3 and KCNA10 on chromosome 1. [provided by RefSeq, Jul 2008]
  • Mouse(16490) potassium voltage-gated channel, shaker-related subfamily, member 2
  • Rat(25468) potassium voltage-gated channel, shaker-related subfamily, member 2
  • cow(539608) potassium voltage-gated channel, shaker-related subfamily, member 2
  • domestic cat(101083868) potassium voltage-gated channel, shaker-related subfamily, member 2
  • dog(404022) potassium voltage-gated channel, shaker-related subfamily, member 2
  • Zebrafish(100537815) potassium voltage-gated channel, shaker-related subfamily, member 2
  • chicken(395117) potassium voltage-gated channel, shaker-related subfamily, member 2
  • naked mole-rat(101717332) potassium voltage-gated channel, shaker-related subfamily, member 2
  • domestic guinea pig(100735605) potassium voltage-gated channel, shaker-related subfamily, member 2
  • sheep(101112012) potassium voltage-gated channel, shaker-related subfamily, member 2

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Antibodies

货号
说明
物种反应性
应用
Anti-Potassium Channel Kv1.2 Antibody, clone K14/16, clone K14/16, from mouse,
物种反应性
rat
应用
immunofluorescence
immunohistochemistry

western blot
ANTI-KCNA2 (C-TERM) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
物种反应性
human
应用
western blot
单克隆抗 KCNA2 小鼠抗, clone S14-16, 1 mg/mL, purified immunoglobulin,
物种反应性
human, mouse, rat, zebrafish
应用
immunohistochemistry
immunoprecipitation (IP)

western blot

Small Molecule - Blocker

货号
说明
物种
盐酸胍 盐酸盐, for molecular biology, ≥99%,
物种
human
盐酸胍 盐酸盐, ≥99% (titration), organic base and chaeotropic agent,
物种
human
盐酸胍 盐酸盐, ≥98%,
物种
human
胍 盐酸盐 溶液, BioUltra, ~8 M in H2O,
物种
human
胍 盐酸盐 溶液, Colorless liquid, 7.8 - 8.3 M, pH- 4.5 - 5.5,
物种
human

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting mouse Kcna2,
物种
mouse
MISSION® esiRNA, targeting human KCNA2,
物种
human