CN
KCNA3
potassium voltage-gated channel, shaker-related subfamily, member 3
别名:
HGK5, HLK3, HPCN3, HUKIII, KV1.3, MK3, PCN3
物种:
Human KCNA3 (3738), Mouse Kcna3 (16491), Rat Kcna3 (29731), cow KCNA3 (525507), domestic cat KCNA3 (101092201), dog KCNA3 (490110), chicken KCNA3 (404303), naked mole-rat Kcna3 (101719045), domestic guinea pig Kcna3 (100721847), sheep KCNA3 (101105466)
UniProtKB ID:
基因ID:
- Human(3738) Summary: Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It belongs to the delayed rectifier class, members of which allow nerve cells to efficiently repolarize following an action potential. It plays an essential role in T-cell proliferation and activation. This gene appears to be intronless and it is clustered together with KCNA2 and KCNA10 genes on chromosome 1. [provided by RefSeq, Jul 2008]
- Mouse(16491) potassium voltage-gated channel, shaker-related subfamily, member 3
- Rat(29731) potassium voltage-gated channel, shaker-related subfamily, member 3
- cow(525507) potassium voltage-gated channel, shaker-related subfamily, member 3
- domestic cat(101092201) potassium voltage-gated channel, shaker-related subfamily, member 3
- dog(490110) potassium voltage-gated channel, shaker-related subfamily, member 3
- chicken(404303) potassium voltage-gated channel, shaker-related subfamily, member 3
- naked mole-rat(101719045) potassium voltage-gated channel, shaker-related subfamily, member 3
- domestic guinea pig(100721847) potassium voltage-gated channel, shaker-related subfamily, member 3
- sheep(101105466) potassium voltage-gated channel, shaker-related subfamily, member 3
- Domestic Rabbit(100328945) potassium voltage-gated channel, shaker-related subfamily, member 3
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Antibodies
货号
说明
物种反应性
应用
Anti-Potassium Channel Kv1.3 Antibody, extracellular domain, Chemicon®, from rabbit,
物种反应性
human, rat
应用
flow cytometry
western blot
western blot
Anti-KV1.3 antibody produced in rabbit, affinity isolated antibody,
物种反应性
human, mouse, rat
应用
ELISA
immunofluorescence
immunohistochemistry
immunofluorescence
immunohistochemistry
Anti-Potassium Channel Kv1.3 Antibody, Chemicon®, from rabbit,
物种反应性
human, mouse, rat
应用
immunohistochemistry
western blot
western blot
Anti-phospho-Kv1.3/KCNA3 (pTyr135) antibody produced in rabbit, affinity isolated antibody,
物种反应性
human, mouse, rat
应用
ELISA
immunofluorescence
immunohistochemistry
western blot
immunofluorescence
immunohistochemistry
western blot
Anti-KCNA3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry
Small Molecule - Blocker
esiRNA
货号
说明
物种