Merck
CN

KCNQ1

potassium voltage-gated channel, KQT-like subfamily, member 1

别名:
ATFB1, ATFB3, JLNS1, KCNA8, KCNA9, KVLQT1, Kv1.9, Kv7.1, LQT, LQT1, RWS, SQT2, WRS
物种:
UniProtKB ID:
基因ID:
  • Human(3784) Summary: This gene encodes a voltage-gated potassium channel required for repolarization phase of the cardiac action potential. This protein can form heteromultimers with two other potassium channel proteins, KCNE1 and KCNE3. Mutations in this gene are associated with hereditary long QT syndrome 1 (also known as Romano-Ward syndrome), Jervell and Lange-Nielsen syndrome, and familial atrial fibrillation. This gene exhibits tissue-specific imprinting, with preferential expression from the maternal allele in some tissues, and biallelic expression in others. This gene is located in a region of chromosome 11 amongst other imprinted genes that are associated with Beckwith-Wiedemann syndrome (BWS), and itself has been shown to be disrupted by chromosomal rearrangements in patients with BWS. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Aug 2011]
  • Mouse(16535) potassium voltage-gated channel, subfamily Q, member 1
  • Rat(84020) potassium voltage-gated channel, KQT-like subfamily, member 1
  • chicken(423090) potassium voltage-gated channel, KQT-like subfamily, member 1
  • naked mole-rat(101725681) potassium voltage-gated channel, KQT-like subfamily, member 1
  • domestic guinea pig(100379230) potassium voltage-gated channel, subfamily Q, member 1
  • sheep(101119596) potassium voltage-gated channel, KQT-like subfamily, member 1
  • domestic cat(101092644) potassium voltage-gated channel, KQT-like subfamily, member 1
  • Horse(100034129) potassium voltage-gated channel, KQT-like subfamily, member 1
  • cow(784876) potassium voltage-gated channel, KQT-like subfamily, member 1
  • dog(483669) potassium voltage-gated channel, KQT-like subfamily, member 1
  • Zebrafish(557498) potassium voltage-gated channel, KQT-like subfamily, member 1

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Antibodies

货号
说明
物种反应性
应用
Anti-KCNQ1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry
Anti-KCNQ1 (C-terminal) antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
物种反应性
human, mouse, rat
应用
ELISA
immunohistochemistry

western blot
Anti-KCNQ1, affinity isolated antibody,
物种反应性
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
应用
immunohistochemistry
western blot
Anti-Potassium Channel KvLQT1 Antibody, CT, Chemicon®, from rabbit,
物种反应性
human, mouse, rat
应用
immunohistochemistry
western blot
Anti-Potassium Channel Kv7.1 (KCNQ1) antibody produced in rabbit, affinity isolated antibody, lyophilized powder,
物种反应性
human, rat
应用
western blot

Small Molecule - Blocker

货号
说明
物种
瑞替加滨, analytical standard,
物种
human
盐酸胍 盐酸盐, for molecular biology, ≥99%,
物种
human
盐酸胍 盐酸盐, ≥99% (titration), organic base and chaeotropic agent,
物种
human
盐酸胍 盐酸盐, ≥98%,
物种
human
胍 盐酸盐 溶液, BioUltra, ~8 M in H2O,
物种
human

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting human KCNQ1,
物种
human
MISSION® esiRNA, targeting mouse Kcnq1,
物种
mouse