Merck
CN

NR3C2

nuclear receptor subfamily 3, group C, member 2

别名:
MCR, MLR, MR, NR3C2VIT
物种:
UniProtKB ID:
基因ID:
  • Human(4306) Summary: This gene encodes the mineralocorticoid receptor, which mediates aldosterone actions on salt and water balance within restricted target cells. The protein functions as a ligand-dependent transcription factor that binds to mineralocorticoid response elements in order to transactivate target genes. Mutations in this gene cause autosomal dominant pseudohypoaldosteronism type I, a disorder characterized by urinary salt wasting. Defects in this gene are also associated with early onset hypertension with severe exacerbation in pregnancy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]
  • Mouse(110784) nuclear receptor subfamily 3, group C, member 2
  • Rat(25672) nuclear receptor subfamily 3, group C, member 2
  • sheep(101107046) nuclear receptor subfamily 3, group C, member 2
  • cow(280861) nuclear receptor subfamily 3, group C, member 2
  • cow(537614) nuclear receptor subfamily 3, group C, member 2
  • domestic cat(101081977) nuclear receptor subfamily 3, group C, member 2
  • Horse(100062570) nuclear receptor subfamily 3, group C, member 2
  • dog(475461) nuclear receptor subfamily 3, group C, member 2
  • chicken(374131) nuclear receptor subfamily 3, group C, member 2
  • domestic guinea pig(100735309) nuclear receptor subfamily 3, group C, member 2
  • Zebrafish(562171) nuclear receptor subfamily 3, group C, member 2

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Small Molecule - Antagonist

货号
说明
物种
Eplerenone, European Pharmacopoeia (EP) Reference Standard, European Pharmacopoeia (EP) Reference Standard,
物种
human
Spironolactone Related Compound A, United States Pharmacopeia (USP) Reference Standard,
物种
human
螺内酯, United States Pharmacopeia (USP) Reference Standard,
物种
human
Eplerenone for system suitability, European Pharmacopoeia (EP) Reference Standard,
物种
human
Eplerenone for peak identification, European Pharmacopoeia (EP) Reference Standard,
物种
human

Antibodies

货号
说明
物种反应性
应用
Anti-Mineralocorticoid Receptor Antibody, clone 2D6, clone 2D6, from mouse,
物种反应性
rat
应用
immunocytochemistry
immunohistochemistry

western blot
抗-盐皮质激素受体抗体,克隆6G1, clone 6G1, from mouse,
物种反应性
mouse, rat
应用
immunocytochemistry
immunohistochemistry

western blot
Anti-NR3C2, (N-terminal) antibody produced in rabbit, affinity isolated antibody,
物种反应性
horse, human
应用
western blot
Anti-NR3C2 antibody produced in rabbit, IgG fraction of antiserum,
物种反应性
human, rabbit
应用
immunohistochemistry
western blot
Anti-NR3C2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
物种反应性
human
应用
immunofluorescence

Proteins

货号
说明
物种
PrEST Antigen NR3C2, Prestige Antigens Powered by Atlas Antibodies, buffered aqueous solution,
物种
human

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting mouse Nr3c2,
物种
mouse
MISSION® esiRNA, targeting human NR3C2,
物种
human