Merck
CN

RXRB

retinoid X receptor, beta

Synonyms:
DAUDI6, H-2RIIBP, NR2B2, RCoR-1
Species:
UniProtKB ID:
Gene ID:
  • Human(6257) Summary: This gene encodes a member of the retinoid X receptor (RXR) family of nuclear receptors which are involved in mediating the effects of retinoic acid (RA). The encoded protein forms homodimers with the retinoic acid, thyroid hormone, and vitamin D receptors, increasing both DNA binding and transcriptional function on their respective response elements. This gene lies within the major histocompatibility complex (MHC) class II region on chromosome 6. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jul 2012]
  • Mouse(20182) retinoid X receptor beta
  • Rat(361801) retinoid X receptor beta
  • dog(481735) retinoid X receptor, beta
  • domestic guinea pig(100732959) retinoid X receptor, beta
  • naked mole-rat(101723696) retinoid X receptor, beta
  • cow(504943) retinoid X receptor, beta
  • domestic cat(101085801) retinoid X receptor, beta
  • sheep(101110798) retinoid X receptor, beta

Custom & Knockdown Gene Products

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  • Custom Gene Products

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Small Molecule - Activator

Product Number
Description
Species
9-cis-Retinoic acid, ≥98% (HPLC),
Species
human
Retinoic acid, ≥98% (HPLC), powder,
Species
mouse, human

Small Molecule - Agonist

Product Number
Description
Species
Bexarotene, ≥98% (HPLC),
Species
human
Acitretin for impurity A identification, European Pharmacopoeia (EP) Reference Standard,
Species
human
Acitretin, ≥98.0% (HPLC),
Species
human
Acitretin, British Pharmacopoeia (BP) Reference Standard,
Species
human
Acitretin, European Pharmacopoeia (EP) Reference Standard,
Species
human

Small Molecule - Antagonist

Product Number
Description
Species
TTNPB, ,
Species
human
Retinoic acid, ≥98% (HPLC), powder,
Species
mouse, human

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-RXRB (AB1) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Application
western blot
Anti-RXRB antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
Monoclonal Anti-RXRB antibody produced in mouse, clone 2E6, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
Monoclonal Anti-RXRB antibody produced in mouse, clone 3C8, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot

Kits

Product Number
Description
Species
CpG WIZ RARβ2 - Methylation specific PCR assay, The components of the CpG WIZ RARbeta2 Amplification Kit include those required for PCR amplification after bisulfite modification of DNA samples. Sufficient reagents are provided to analyze 25 samples.,
Species
human

Small Molecule - Ligand

Product Number
Description
Species
9-cis-Retinoic acid, ≥98% (HPLC),
Species
human
TTNPB, ,
Species
human
Retinoic acid, ≥98% (HPLC), powder,
Species
mouse, human

Proteins

Product Number
Description
Species
RXR, β human, recombinant, expressed in insect cells, ≥80% (SDS-PAGE),
Species
human
RXRβ isoform, GST tagged human, recombinant, expressed in E. coli, ≥80% (SDS-PAGE),
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Rxrb,
Species
mouse
MISSION® esiRNA, targeting human RXRB,
Species
human