Merck
CN

SCN5A

sodium channel, voltage-gated, type V, alpha subunit

别名:
CDCD2, CMD1E, CMPD2, HB1, HB2, HBBD, HH1, ICCD, IVF, LQT3, Nav1.5, PFHB1, SSS1, VF1
物种:
Human SCN5A (6331), Mouse Scn5a (20271), Rat Scn5a (25665), Domestic Rabbit SCN5A (100009516), domestic guinea pig Scn5a (100723340), naked mole-rat Scn5a (101710111), domestic cat SCN5A (101100994), Horse SCN5A (100034027), cow SCN5A (282061), sheep SCN5A (101111582) ...展开
UniProtKB ID:
Q14524, A5H1P8, A6N922, A6N923, B2RTU0, E9PEF3, E9PEK2, E9PFW7
基因ID:
  • Human(6331) Summary: The protein encoded by this gene is an integral membrane protein and tetrodotoxin-resistant voltage-gated sodium channel subunit. This protein is found primarily in cardiac muscle and is responsible for the initial upstroke of the action potential in an electrocardiogram. Defects in this gene are a cause of long QT syndrome type 3 (LQT3), an autosomal dominant cardiac disease. Alternative splicing results in several transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
  • Mouse(20271) sodium channel, voltage-gated, type V, alpha
  • Rat(25665) sodium channel, voltage-gated, type V, alpha subunit
  • Domestic Rabbit(100009516) sodium channel, voltage-gated, type V, alpha subunit
  • domestic guinea pig(100723340) sodium channel, voltage-gated, type V, alpha subunit
  • naked mole-rat(101710111) sodium channel, voltage-gated, type V, alpha subunit
  • domestic cat(101100994) sodium channel, voltage-gated, type V, alpha subunit
  • Horse(100034027) sodium channel, voltage-gated, type V, alpha subunit
  • cow(282061) sodium channel, voltage-gated, type V, alpha subunit
  • sheep(101111582) sodium channel, voltage-gated, type V, alpha subunit
  • chicken(395947) sodium channel, voltage-gated, type V, alpha subunit
  • dog(403497) sodium channel, voltage-gated, type V, alpha subunit

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Antibodies

货号
说明
物种反应性
应用
S1946
Anti-Sodium Channel NaV1.5 human antibody produced in rabbit, affinity isolated antibody, lyophilized powder,
物种反应性
human
应用
western blot
SAB2107930
Anti-SCN5A antibody produced in rabbit, affinity isolated antibody,
物种反应性
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
应用
western blot
AB5493
Anti-Sodium Channel Nav1.5 Antibody, pain, Chemicon®, from rabbit,
物种反应性
rat
应用
western blot
HPA063346
Anti-SCN5A antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunofluorescence
SAB2109012
Anti-SCN5A (C-terminal) antibody produced in rabbit, affinity isolated antibody,
物种反应性
bovine, canine, guinea pig, horse, human, mouse, rat
应用
immunohistochemistry
western blot

Small Molecule - Blocker

货号
说明
物种
F6777
氟卡尼 乙酸盐, ,
物种
human
F-017
(±)-Flecainide solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
物种
human
1270800
氟卡尼 乙酸盐, United States Pharmacopeia (USP) Reference Standard,
物种
human
F0120000
氟卡尼 乙酸盐, European Pharmacopoeia (EP) Reference Standard,
物种
human
BP676
氟卡尼 乙酸盐, British Pharmacopoeia (BP) Reference Standard,
物种
human

Small Molecule - Ligand

货号
说明
物种
L3791
拉莫三嗪, ≥98%, powder,
物种
rat, human

esiRNA

货号
说明
物种
EHU151881
MISSION® esiRNA, targeting human SCN5A,
物种
human