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F-017

(±)-Flecainide solution

Name: (±)-Flecainide solution
Brand: CERILLIAN

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant^®

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关于此项目

经验公式（希尔记法）:

C₁₇H₂₀F₆N₂O₃

化学文摘社编号:

54143-55-4

分子量:

414.34

NACRES:

NA.24

PubChem Substance ID:

329799633

UNSPSC Code:

41116107

EC Number:

200-659-6

MDL number:

MFCD00864713

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属性

grade

certified reference material

Quality Level

300

form

liquid

feature

Snap-N-Spike^®/Snap-N-Shoot^®

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant^®

concentration

1.0 mg/mL in methanol

technique(s)

gas chromatography (GC): suitable, liquid chromatography (LC): suitable

application(s)

clinical testing

format

single component solution

storage temp.

−20°C

SMILES string

O=C(NCC1CCCCN1)C2=CC(OCC(F)(F)F)=CC=C2OCC(F)(F)F

InChI

1S/C17H20F6N2O3/c18-16(19,20)9-27-12-4-5-14(28-10-17(21,22)23)13(7-12)15(26)25-8-11-3-1-2-6-24-11/h4-5,7,11,24H,1-3,6,8-10H2,(H,25,26)

InChI key

DJBNUMBKLMJRSA-UHFFFAOYSA-N

Gene Information

human ... SCN5A(6331)

说明

General description

Flecainide, marketed under trade names such as Almarytm, Apocard, Ecrinal^®, and Flécaine, is a class Ic antiarrhythmic drug used to prevent and treat a variety of cardiac arrhythmias. This Certified Spiking Solution^® is suitable for use as a starting material in the preparation of calibrators, controls, or linearity standards in flecainide therapeutic drug monitoring methods by LC/MS or LC that ensure patients remain within the drug′s narrow therapeutic range.

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

CERTIFIED SPIKING SOLUTION is a registered trademark of Cerilliant Corporation

Ecrinal is a registered trademark of Laboratoires Asepta Corporation Monaco

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

pictograms

GHS02,GHS06,GHS08

signalword

Danger

hcodes

H225,H301 + H311 + H331,H370

pcodes

P210 - P233 - P280 - P301 + P310 - P303 + P361 + P353 - P304 + P340 + P311

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

target_organs

Eyes,Central nervous system

存储类别

3 - Flammable liquids

wgk

WGK 2

flash_point_f

49.5 °F - closed cup

flash_point_c

9.7 °C - closed cup

法规信息

危险化学品

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Catecholaminergic polymorphic ventricular tachycardia.

Antoine Leenhardt et al.

Circulation. Arrhythmia and electrophysiology, 5(5), 1044-1052 (2012-10-02)

Antiarrhythmic drug treatment after cardioversion of atrial fibrillation.

Ajay Vallakati et al.

Lancet (London, England), 380(9852), 1467-1468 (2012-10-30)

[CME ECG 40. Vertigo with ST elevation in V2. Brugada syndrome].

Ardan M Saguner et al.

Praxis, 102(5), 305-307 (2013-03-01)

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全球贸易项目编号

货号	GTIN
F-017-1ML	04061833610145

主要文件

(±)-Flecainide solution

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant^®