Merck
CN

SCN8A

sodium channel, voltage gated, type VIII, alpha subunit

别名:
CERIII, CIAT, EIEE13, MED, NaCh6, Nav1.6, PN4
物种:
UniProtKB ID:
基因ID:
  • Human(6334) Summary: This gene encodes a member of the sodium channel alpha subunit gene family. The encoded protein forms the ion pore region of the voltage-gated sodium channel. This protein is essential for the rapid membrane depolarization that occurs during the formation of the action potential in excitable neurons. Mutations in this gene are associated with mental retardation, pancerebellar atrophy and ataxia. Alternate splicing results in multiple transcript variants.[provided by RefSeq, May 2010]
  • Mouse(20273) sodium channel, voltage-gated, type VIII, alpha
  • Rat(29710) sodium channel, voltage gated, type VIII, alpha subunit
  • chicken(100857835) sodium channel, voltage gated, type VIII, alpha subunit
  • dog(477604) sodium channel, voltage gated, type VIII, alpha subunit
  • Horse(100052777) sodium channel, voltage gated, type VIII, alpha subunit
  • cow(537277) sodium channel, voltage gated, type VIII, alpha subunit
  • naked mole-rat(101711868) sodium channel, voltage gated, type VIII, alpha subunit
  • domestic guinea pig(100734003) sodium channel, voltage gated, type VIII, alpha subunit
  • sheep(101113744) sodium channel, voltage gated, type VIII, alpha subunit
  • domestic cat(101096578) sodium channel, voltage gated, type VIII, alpha subunit
  • chicken(426869) sodium channel, voltage gated, type VIII, alpha subunit

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Antibodies

货号
说明
物种反应性
应用
Monoclonal Anti-SCN8A antibody produced in mouse, clone 4G7, purified immunoglobulin, buffered aqueous solution,
物种反应性
human, mouse, rat
应用
ELISA
immunofluorescence

western blot
抗-SCN8A钠通道抗体, Chemicon®, from rabbit,
物种反应性
mouse, rat
应用
immunocytochemistry
immunohistochemistry

western blot
Anti-SCN8A, affinity isolated antibody,
物种反应性
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
应用
western blot
Anti-SCN8A antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunofluorescence
Anti-SCN8A antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunofluorescence

Small Molecule - Blocker

货号
说明
物种
利多卡因, Pharmaceutical Secondary Standard; Certified Reference Material,
物种
human
利多卡因, Pharmaceutical Secondary Standard; Certified Reference Material,
物种
human
普鲁卡因 盐酸盐, ≥97%,
物种
human
普鲁卡因酰胺 盐酸盐, ≥98% (HPLC),
物种
human
拉莫三嗪, Pharmaceutical Secondary Standard; Certified Reference Material,
物种
human

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting mouse Scn8a,
物种
mouse