Merck
CN

HTR3B

5-hydroxytryptamine (serotonin) receptor 3B, ionotropic

Synonyms:
5-HT3B
Species:
UniProtKB ID:
Gene ID:
  • Human(9177) Summary: The product of this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes subunit B of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. It is not functional as a homomeric complex, but a pentaheteromeric complex with subunit A (HTR3A) displays the full functional features of this receptor. [provided by RefSeq, Aug 2011]
  • Mouse(57014) 5-hydroxytryptamine (serotonin) receptor 3B
  • Rat(58963) 5-hydroxytryptamine (serotonin) receptor 3B, ionotropic
  • domestic cat(101082340) 5-hydroxytryptamine (serotonin) receptor 3B, ionotropic
  • sheep(101110267) 5-hydroxytryptamine (serotonin) receptor 3B, ionotropic
  • cow(541055) 5-hydroxytryptamine (serotonin) receptor 3B, ionotropic
  • naked mole-rat(101726074) 5-hydroxytryptamine (serotonin) receptor 3B, ionotropic
  • domestic guinea pig(100736034) 5-hydroxytryptamine (serotonin) receptor 3B, ionotropic
  • dog(611236) 5-hydroxytryptamine (serotonin) receptor 3B, ionotropic

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Small Molecule - Agonist

Product Number
Description
Species
SR 57227A, solid,
Species
human
Metoclopramide hydrochloride, solid,
Species
human
Quipazine maleate salt, ,
Species
human

Small Molecule - Allosteric Modulator

Product Number
Description
Species
DCEBIO, ≥98% (HPLC), solid,
Species
human

Small Molecule - Antagonist

Product Number
Description
Species
Metoclopramide hydrochloride, solid,
Species
human
Amisulpride, European Pharmacopoeia (EP) Reference Standard,
Species
human
Amisulpride, British Pharmacopoeia (BP) Reference Standard,
Species
human
Amisulpride for system suitability, European Pharmacopoeia (EP) Reference Standard,
Species
human
Amisulpride for system suitability, British Pharmacopoeia (BP) Reference Standard,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-HTR3B antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Anti-HTR3B antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Anti-HTR3B antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry

western blot

Small Molecule - Blocker

Product Number
Description
Species
Trimipramine maleate salt, ≥98% (TLC), powder,
Species
human

Small Molecule - Inhibitor

Product Number
Description
Species
S-(+)-Fluoxetine hydrochloride, ≥98% (HPLC), solid,
Species
human
R-(−)-Fluoxetine hydrochloride, >98% (HPLC), solid,
Species
human
Fluvoxamine maleate, solid,
Species
human
Sertraline hydrochloride, ≥98% (HPLC),
Species
human
Citalopram hydrobromide, ≥98% (HPLC),
Species
human

Small Molecule - Ligand

Product Number
Description
Species
Nω-Methyl-5-hydroxy­trypt­amine oxalate salt, ≥90% (HPLC),
Species
human

Small Molecule - Metabolite

Product Number
Description
Species
5-Hydroxyindole-3-acetic acid, ≥98% (HPLC), crystalline,
Species
human

Small Molecule - Precursor

Product Number
Description
Species
5-Hydroxy-L-tryptophan, powder,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Htr3b,
Species
mouse