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Merck
CN

142670

Chloromethyl ethyl ether

95%

Synonym(s):

(Chloromethoxy)ethane, Ethoxychloromethane, Ethoxymethyl chloride, Ethyl chloromethyl ether

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About This Item

Linear Formula:
C2H5OCH2Cl
CAS Number:
Molecular Weight:
94.54
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352101
EC Number:
221-687-5
MDL number:
Assay:
95%
Form:
liquid
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Quality Segment

assay

95%

form

liquid

reaction suitability

reactivity: alcohol reactive, reagent type: protection reagent

refractive index

n20/D 1.404 (lit.)

bp

82 °C (lit.)

density

1.019 g/mL at 25 °C (lit.)

functional group

chloro, ether

storage temp.

2-8°C

SMILES string

CCOCCl

InChI

1S/C3H7ClO/c1-2-5-3-4/h2-3H2,1H3

InChI key

FCYRSDMGOLYDHL-UHFFFAOYSA-N

Application

Chloromethyl ethyl ether can be used to prepare:
  • 6-Benzyl-1-(ethoxymethyl)-5-iodopyrimidine-2,4(1H,3H)-dione, a key intermediate in the preparation of MKC-442 analog.
  • Acylation catalyst for alcohols named 1,3-bis-[(R)-1-(2-naphthyl)ethyl]imidazoliumchloride by reacting with glyoxal-bis-[(R)-1-(2-naphthyl)ethyl]imine.



signalword

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Flam. Liq. 2

Storage Class

3 - Flammable liquids

wgk

WGK 3

flash_point_f

66.2 °F - closed cup

flash_point_c

19 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter



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