15500
Boc-Ser-OH
≥99.0% (T), for peptide synthesis
Synonym(s):
N-(tert-Butoxycarbonyl)-L-serine, Boc-L-serine
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About This Item
Linear Formula:
HOCH2CH(COOH)NHCOOC(CH3)3
CAS Number:
Molecular Weight:
205.21
NACRES:
NA.22
PubChem Substance ID:
eCl@ss:
32160406
UNSPSC Code:
12352209
EC Number:
221-867-3
MDL number:
Beilstein/REAXYS Number:
2212252
Product Name
Boc-Ser-OH, ≥99.0% (T)
Quality Level
assay
≥99.0% (T)
optical activity
[α]20/D −3.5±0.5°, c = 2% in acetic acid
reaction suitability
reaction type: Boc solid-phase peptide synthesis
mp
91 °C (dec.) (lit.)
application(s)
peptide synthesis
storage temp.
2-8°C
SMILES string
CC(C)(C)OC(=O)N[C@@H](CO)C(O)=O
InChI
1S/C8H15NO5/c1-8(2,3)14-7(13)9-5(4-10)6(11)12/h5,10H,4H2,1-3H3,(H,9,13)(H,11,12)/t5-/m0/s1
InChI key
FHOAKXBXYSJBGX-YFKPBYRVSA-N
General description
Boc-Ser-OH is an amino acid derivative.
Application
Boc-Ser-OH may be used in the synthesis of the following:
- 2-(N-Fmoc)-3-(N-Boc-N-methoxy)-diaminopropanoic acid (Fmoc: 9-fluorenylmethoxycarbonyl; Boc: t-butyloxycarbonyl)
- Boc-Ser-Leu-OMe
- cyclic peptide synthesis
- benzylsulfonyl-D-Ser-Ser-4-amidinobenzylamide
Building block in peptide synthesis. Starting material for the synthesis of various α-amino acids via the β-lactone.
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Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Synthesis of cyclic peptides via O-N-acyl migration.
Lecaillon J, et al.
Tetrahedron Letters, 49(31), 4674-4676 (2008)
Gema Villa-Fombuena et al.
Development (Cambridge, England), 148(18) (2021-08-10)
Drosophila female germline stem cells (GSCs) are found inside the cellular niche at the tip of the ovary. They undergo asymmetric divisions to renew the stem cell lineage and to produce sibling cystoblasts that will in turn enter differentiation. GSCs
O García-Suárez et al.
Immunology, 94(2), 235-241 (1998-09-19)
Increasing evidence suggests that some members of the neurotrophic factor family of neurotrophins could be implicated in the regulation of immune responses. Neurotrophins, as well as their tyrosine kinase signal-transducing receptors (the so-called Trk neurotrophin receptors), have been detected in
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 15500-5G | 04061832641614 |
| 15500-25G | 04061832641607 |