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Merck
CN

286427

L-Leucinamide hydrochloride

99%

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About This Item

Linear Formula:
(CH3)2CHCH2CH(NH2)CONH2·HCl
CAS Number:
Molecular Weight:
166.65
UNSPSC Code:
12352209
NACRES:
NA.22
PubChem Substance ID:
EC Number:
233-952-2
Beilstein/REAXYS Number:
4237021
MDL number:
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InChI key

VSPSRRBIXFUMOU-JEDNCBNOSA-N

InChI

1S/C6H14N2O.ClH/c1-4(2)3-5(7)6(8)9;/h4-5H,3,7H2,1-2H3,(H2,8,9);1H/t5-;/m0./s1

SMILES string

Cl.CC(C)C[C@H](N)C(N)=O

assay

99%

optical activity

[α]25/D +10°, c = 5 in H2O

reaction suitability

reaction type: solution phase peptide synthesis

mp

254-256 °C (lit.)

application(s)

peptide synthesis

Quality Level

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

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A conductometric method for the assay of amidase and peptidase activities.
C R Hill et al.
Analytical biochemistry, 120(1), 165-175 (1982-02-01)
Andrew R Conrad et al.
The journal of physical chemistry. A, 115(34), 9676-9681 (2011-05-12)
Rotational spectra were recorded for two isotopic species of two conformers of the amide derivative of leucine in the range of 10.5-21 GHz and fit to a rigid rotor Hamiltonian. Ab initio calculations at the MP2/6-311++G(d,p) level identified the low
[Leucinamide specific cytosol leucine aminopeptidase].
T Kanno
Rinsho byori. The Japanese journal of clinical pathology, 30(5), 502-506 (1982-05-01)
Determination of the enantiomers of ketoprofen in blood plasma by ion-pair extraction and high-performance liquid chromatography of leucinamide derivatives.
S Björkman
Journal of chromatography, 414(2), 465-471 (1987-03-06)
E A Permiakov et al.
Bioorganicheskaia khimiia, 28(1), 11-15 (2002-03-06)
The kinetics of the reaction of Boc-Xaa fluorophenyl esters (where Xaa = Ala, Val, Phe, Ser, Leu, Gly, Met, Pro, or Ile) with leucinamide was studied measuring changes in the fluorescence emission at 375 nm of the fluorophenyl chromophore accompanying

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