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289647

3-Amino-4-hydroxybenzoic acid

Name: 3-Amino-4-hydroxybenzoic acid
Brand: ALDRICH

97%, for peptide synthesis

Synonym(s):

4-Hydroxy-3-aminobenzoic acid

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About This Item

Linear Formula:

H₂NC₆H₃(OH)CO₂H

CAS Number:

1571-72-8

Molecular Weight:

153.14

NACRES:

NA.22

PubChem Substance ID:

24857208

eCl@ss:

32160406

UNSPSC Code:

12352106

EC Number:

216-390-2

MDL number:

MFCD00007697

Beilstein/REAXYS Number:

972238

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Properties

Product Name

3-Amino-4-hydroxybenzoic acid, 97%

Quality Level

200

assay

97%

form

solid

reaction suitability

reaction type: solution phase peptide synthesis

mp

208 °C (dec.) (lit.)

application(s)

peptide synthesis

SMILES string

Nc1cc(ccc1O)C(O)=O

InChI

1S/C7H7NO3/c8-5-3-4(7(10)11)1-2-6(5)9/h1-3,9H,8H2,(H,10,11)

InChI key

MRBKRZAPGUCWOS-UHFFFAOYSA-N

Description

pictograms

GHS07

signalword

Warning

hcodes

H302,H315,H319,H335

pcodes

P261 - P264 - P271 - P301 + P312 - P302 + P352 - P305 + P351 + P338

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Arylamine N-acetyltransferase responsible for acetylation of 2-aminophenols in Streptomyces griseus.

Hirokazu Suzuki et al.

Journal of bacteriology, 189(5), 2155-2159 (2006-12-13)

An arylamine N-acetyltransferase (NAT) responsible for the N acetylation of exogenous 3-amino-4-hydroxybenzoic acid in Streptomyces griseus was identified and characterized. This enzyme was distinct from other eukaryotic and bacterial NATs in that it acetylated various 2-aminophenol derivatives more effectively than

Vitamin C in combination with inhibition of mutant IDH1 synergistically activates TET enzymes and epigenetically modulates gene silencing in colon cancer cells.

Christian Gerecke et al.

Epigenetics, 15(3), 307-322 (2019-09-12)

Mutations in the enzyme isocitrate dehydrogenase 1 (IDH1) lead to metabolic alterations and a sustained formation of 2-hydroxyglutarate (2-HG). 2-HG is an oncometabolite as it inhibits the activity of α-ketoglutarate-dependent dioxygenases such as ten-eleven translocation (TET) enzymes. Inhibitors of mutant

Experience with cheetan in management of HIV infection.

J Chege et al.

East African medical journal, 74(7), 460-461 (1997-07-01)

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Global Trade Item Number

SKU	GTIN
289647-5G	04061826284346
289647-25G	04061826284339