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Merck
CN

324787

Sigma-Aldrich

2,2,2-Trifluoroethanesulfonyl chloride

99%

Synonym(s):

Tresyl chloride

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About This Item

Linear Formula:
CF3CH2SO2Cl
CAS Number:
1648-99-3
Molecular Weight:
182.55
Beilstein:
1860983
EC Number:
216-713-7
MDL number:
MFCD00007458
UNSPSC Code:
12352101
PubChem Substance ID:
24859467
NACRES:
NA.22

Key Documents

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Assay

99%

form

liquid

refractive index

n20/D 1.388 (lit.)

bp

140-141 °C (lit.)
64-67 °C/45 mmHg (lit.)

density

1.651 g/mL at 25 °C (lit.)

functional group

fluoro

storage temp.

2-8°C

SMILES string

FC(F)(F)CS(Cl)(=O)=O

InChI

1S/C2H2ClF3O2S/c3-9(7,8)1-2(4,5)6/h1H2

InChI key

CXCHEKCRJQRVNG-UHFFFAOYSA-N

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Related Categories

Pictograms

Corrosion
GHS05

Signal Word

Danger

Hazard Statements

H314

Hazard Classifications

Skin Corr. 1B

Storage Class Code

8A - Combustible corrosive hazardous materials

WGK

WGK 3

Flash Point(F)

161.6 °F - closed cup

Flash Point(C)

72 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
MKCX4599
0000089619
0000074625
0000081415
0000038412

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C Delgado et al.
British journal of cancer, 73(2), 175-182 (1996-01-01)
Polyethylene glycol (PEG) modification of a chimeric Fab' fragment (F9) of A5B7 (alpha-CEA), using an improved coupling method, increases its specificity for subcutaneous LS174T tumours. PEGylation increased the area under the concentration-time curve (AUC0-144) in all tissues but there were
V Bille et al.
European journal of biochemistry, 160(2), 343-348 (1986-10-15)
Yeast alcohol dehydrogenase was successfully immobilized on tresyl-chloride-activated agarose; the optimized conditions allowed an enzyme activity recovery of over 90%. Comparison of free and immobilized enzyme properties showed an unchanged intrinsic activation energy of the reaction and a shift of
Annie Chen et al.
Langmuir : the ACS journal of surfaces and colloids, 25(23), 13510-13515 (2009-11-26)
A 10-fold improvement in the signal-to-noise (S/N) ratio of an optically encoded silica particle-based immunoassay was achieved through incorporating a protein resistant poly(ethylene glycol) (PEG) surface layer and optimizing antibody immobilization conditions. PEG was activated using 2,2,2-trifluoroethanesulfonyl chloride (tresyl) and
Markus Gantert et al.
Pharmaceutical research, 26(3), 529-538 (2008-11-19)
The challenge in developing liposomes to be used in active drug targeting is to design a method that can be used for modifying liposomal membranes that is applicable for a number of different specific ligands. In this study, the post
T Hayakawa et al.
Journal of biomedical materials research. Part B, Applied biomaterials, 73(2), 271-276 (2005-01-28)
The immobilization of cell-adhesive proteins onto titanium implants improves biological response at the implant-tissue interface. Previous studies demonstrated the easy and direct attachment of fibronectin onto titanium with the use of a 2,2,2-trifluoroethanesulfonyl chloride (tresyl chloride) activation technique. The present
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