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359807

Z-Phe-OH

99%

Synonym(s):

N-(Carbobenzyloxy)-L-phenylalanine, Z-L-Phenylalanine

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About This Item

Linear Formula:
C6H5CH2CH(NHCOOCH2C6H5)COOH
CAS Number:
1161-13-3
Molecular Weight:
299.32
NACRES:
NA.22
PubChem Substance ID:
24862110
eCl@ss:
32160406
UNSPSC Code:
12352209
EC Number:
214-599-3
MDL number:
MFCD00020418
Beilstein/REAXYS Number:
2222826
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Quality Level

200

assay

99%

optical activity

[α]20/D +5°, c = 5 in acetic acid

reaction suitability

reaction type: solution phase peptide synthesis

mp

85-87 °C (lit.)

application(s)

peptide synthesis

SMILES string

OC(=O)[C@H](Cc1ccccc1)NC(=O)OCc2ccccc2

InChI

1S/C17H17NO4/c19-16(20)15(11-13-7-3-1-4-8-13)18-17(21)22-12-14-9-5-2-6-10-14/h1-10,15H,11-12H2,(H,18,21)(H,19,20)/t15-/m0/s1

InChI key

RRONHWAVOYADJL-HNNXBMFYSA-N

Biochem/physiol Actions

Inhibitor of thermolysin

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
MKCW1500
MKCR8037
MKCN5022
MKCJ5186
MKBW5261V

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S Stoeva
International journal of peptide and protein research, 37(4), 325-330 (1991-04-01)
Diethylpyrocarbonate (DEPC) inactivated the neutral zinc proteinase from Bacillus mesentericus strain 76/Bacillus subtilis (MCP 76) by ethoxycarbonylation completely. Exposure of the enzyme to DEPC together with the competitive inhibitor Z-L-phenylalanine prevented the loss of activity toward both peptide and protein
J Wiese et al.
Biomedica biochimica acta, 50(10-11), S90-S93 (1991-01-01)
The alpha-glyceryl esters of Z-Gly, Z-Phe and Z-Tyr were synthesized and their use for protease catalyzed peptide synthesis was studied. Three enzymes isolated from crude papain were compared in their catalytic potency. Syntheses with alpha-chymotrypsin were performed in a biphasic
Dhruvkumar Soni et al.
Biomaterials, 222, 119441-119441 (2019-09-01)
While antiretroviral therapy (ART) has revolutionized treatment and prevention of human immunodeficiency virus type one (HIV-1) infection, regimen adherence, viral mutations, drug toxicities and access stigma and fatigue are treatment limitations. These have led to new opportunities for the development
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Global Trade Item Number

SKUGTIN
359807-25G04061831813685