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Merck
CN

374229

Boc-Tyr-OH

98%

Synonym(s):

N-(tert-Butoxycarbonyl)-L-tyrosine, Boc-L-tyrosine

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About This Item

Linear Formula:
4-(HO)C6H4CH2CH(COOH)NHC(O)OC(CH3)3
CAS Number:
Molecular Weight:
281.30
UNSPSC Code:
12352209
NACRES:
NA.22
PubChem Substance ID:
EC Number:
223-613-7
Beilstein/REAXYS Number:
2816406
MDL number:
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Product Name

Boc-Tyr-OH, 98%

InChI key

CNBUSIJNWNXLQQ-NSHDSACASA-N

InChI

1S/C14H19NO5/c1-14(2,3)20-13(19)15-11(12(17)18)8-9-4-6-10(16)7-5-9/h4-7,11,16H,8H2,1-3H3,(H,15,19)(H,17,18)/t11-/m0/s1

SMILES string

CC(C)(C)OC(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O

assay

98%

form

solid

optical activity

[α]20/D +3.0°, c = 2 in acetic acid

reaction suitability

reaction type: Boc solid-phase peptide synthesis

mp

133-135 °C (lit.)

application(s)

peptide synthesis

Quality Level

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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

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Qi Zhao et al.
Nutrition & metabolism, 15, 57-57 (2018-08-18)
Individuals' peak bone mineral density (BMD) achieved and maintained at ages 20-40 years is the most powerful predictor of low bone mass and osteoporotic fractures later in life. The aim of this study was to identify metabolomic factors associated with peak
M L Da Silva et al.
Archives of biochemistry and biophysics, 312(1), 151-157 (1994-07-01)
The N-linked oligosaccharides from porcine fibrinogen were purified following their release from glycopeptides using N-glycosidase F. In separate experiments, both sialyl and asialyl oligosaccharides were prepared from 5 g of fibrinogen. The reducing oligosaccharides were reacted with ammonium bicarbonate to
Karoly Toth et al.
Antiviral research, 153, 1-9 (2018-03-07)
Human adenoviruses (AdV) cause generally mild infections of the respiratory and GI tracts as well as some other tissues. However, AdV can cause serious infection in severely immunosuppressed individuals, especially pediatric patients undergoing allogeneic hematopoietic stem cell transplantation, where mortality
Yifan Wang et al.
ACS catalysis, 9(6), 4764-4776 (2019-07-30)
LmbB2 is a peroxygenase-like enzyme that hydroxylates L-tyrosine to L-3,4-dihydroxyphenylalanine (DOPA) in the presence of hydrogen peroxide. However, its heme cofactor is ligated by a proximal histidine, not cysteine. We show that LmbB2 can oxidize L-tyrosine analogs with ring-deactivated substituents
Esmaeil Salimi et al.
International journal of pharmaceutics, 550(1-2), 200-206 (2018-08-28)
To overcome the mucus layer and cell membrane barrier, self-emulsifying drug delivery systems (SEDDS) exhibiting negative zeta potential, switching to positive values when having reached the cell membrane is a promising approach. Accordingly, a novel conjugate was synthesized by covalent

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