385530
N,N,N′,N′-Tetramethyl-O-(N-succinimidyl)uronium tetrafluoroborate
97%, for peptide synthesis
Synonym(s):
O-(N-Succinimidyl)-N,N,N′,N′-tetramethyluronium tetrafluoroborate, TSTU
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About This Item
Empirical Formula (Hill Notation):
C9H16BF4N3O3
CAS Number:
Molecular Weight:
301.05
UNSPSC Code:
12352107
PubChem Substance ID:
NACRES:
NA.22
MDL number:
Product Name
N,N,N′,N′-Tetramethyl-O-(N-succinimidyl)uronium tetrafluoroborate, 97%
Quality Level
assay
97%
reaction suitability
reaction type: Coupling Reactions
mp
198-201 °C (lit.)
application(s)
peptide synthesis
functional group
amine, imide
storage temp.
2-8°C
SMILES string
F[B-](F)(F)F.CN(C)C(\ON1C(=O)CCC1=O)=[N+](\C)C
InChI
1S/C9H16N3O3.BF4/c1-10(2)9(11(3)4)15-12-7(13)5-6-8(12)14;2-1(3,4)5/h5-6H2,1-4H3;/q+1;-1
InChI key
YEBLHMRPZHNTEK-UHFFFAOYSA-N
General description
N,N,N′,N′-Tetramethyl-O-(N-succinimidyl)uronium tetrafluoroborate is commonly used for the conversion of carboxylic acid into the corresponding N-hydroxysuccinimidyl (NHS) ester.
Application
N,N,N′,N′-Tetramethyl-O-(N-succinimidyl)uronium tetrafluoroborate may be used in the synthesis of N-succinimidyl 4-[18F]fluorobenzoate ([18F]SFB), a 18F-labeled agent used for labeling biomarkers. it may also be used for the activation of carboxylic group of C16-chained alkanethiols that are used in developing surface plasmon resonance (SPR) sensors.
Reactant for:
Linking sensor molecules with amino groups to amino functionalized AFM tips
Reactant for synthesis of:
A polymer supported oranotin reagent for prosthetic group labeling of biological macromolecules with radioiodine
L-Rhamnose antigen
Fluorinated rhodamines for optical microscopy and nanoscopy
c(RGDyK) targeted SN38 prodrug
Polyelectrolytes for thin film construction
Linking sensor molecules with amino groups to amino functionalized AFM tips
Reactant for synthesis of:
A polymer supported oranotin reagent for prosthetic group labeling of biological macromolecules with radioiodine
L-Rhamnose antigen
Fluorinated rhodamines for optical microscopy and nanoscopy
c(RGDyK) targeted SN38 prodrug
Polyelectrolytes for thin film construction
signalword
Warning
hcodes
Hazard Classifications
Skin Sens. 1A
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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Global Trade Item Number
| SKU | GTIN |
|---|---|
| 385530-5G | 04061831966497 |
| 385530-1G | 04061826732564 |