Key Documents

View All Documentation

412201

L-Serine methyl ester hydrochloride

Name: <SC>L</SC>-Serine methyl ester hydrochloride
Brand: ALDRICH

98%, for peptide synthesis

Synonym(s):

L-Serine methyl ester·HCl

Select a Size

Change View

About This Item

Linear Formula:

HOCH₂CH(NH₂)COOCH₃ · HCl

CAS Number:

5680-80-8

Molecular Weight:

155.58

NACRES:

NA.22

PubChem Substance ID:

24865794

eCl@ss:

32160406

UNSPSC Code:

12352209

EC Number:

227-140-7

MDL number:

MFCD00063680

Beilstein/REAXYS Number:

3559591

Technical Service

Need help? Our team of experienced scientists is here for you.

Let Us Assist

Properties

Product Name

L-Serine methyl ester hydrochloride, 98%

Quality Level

100

assay

98%

form

powder

optical activity

[α]20/D +3.4°, c = 4 in methanol

reaction suitability

reaction type: solution phase peptide synthesis

mp

163 °C (dec.) (lit.)

application(s)

peptide synthesis

SMILES string

Cl.COC(=O)[C@@H](N)CO

InChI

1S/C4H9NO3.ClH/c1-8-4(7)3(5)2-6;/h3,6H,2,5H2,1H3;1H/t3-;/m0./s1

InChI key

NDBQJIBNNUJNHA-DFWYDOINSA-N

Description

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Theoretical evidence for pyramidalized bicyclic serine enolates in highly diastereoselective alkylations.

Carlos Aydillo et al.

Chemistry (Weinheim an der Bergstrasse, Germany), 13(17), 4840-4848 (2007-03-17)

A new chiral serine equivalent and its enantiomer have been synthesized from (S)- and (R)-N-Boc-serine methyl esters (Boc: tert-butyloxycarbonyl). The use of these compounds as chiral building blocks has been demonstrated in the synthesis of alpha-alkyl alpha-amino acids by diastereoselective

Contribution of the anomeric effect to the solution and crystal structure of [1S,2S,6S,7s]-1,6-diaza-4,9-dioxa-2,7-dimethoxycarbonylbicyclo[4.4.1]undecane, a condensation product of L-serine methyl ester with formaldehyde.

J Sélambarom et al.

Carbohydrate research, 330(1), 43-51 (2001-02-24)

The reaction of L-serine methyl ester hydrochloride (1) with paraformaldehyde (2) in dichloromethane in the presence of triethylamine afforded a novel compound: [lS,2S,6S,7S]-1,6-diaza-4,9-dioxa-2,7-dimethoxycarbonylbicyclo[4.4.1]undecane (4) as a 2:3 adduct of 1 with 2. 1H and 13C NMR spectroscopy were unable to

Aziridinium from N,N-dibenzyl serine methyl ester: synthesis of enantiomerically pure beta-amino and alpha,beta-diamino esters.

Cédric Couturier et al.

Organic letters, 8(10), 2183-2186 (2006-05-05)

[reaction: see text] Reaction of N,N-dibenzyl-O-methylsulfonyl serine methyl ester with a variety of heteronucleophiles (sodium azide, sodium phthalimide, amines, thiols) and carbanions (sodium malonate) gave, via an aziridinium intermediate, the corresponding beta-amino or alpha,beta-diamino ester in good to excellent yield.

View All Related Papers

Global Trade Item Number

SKU	GTIN
412201-5G	04061832075303
412201-25G	04061832075266