Skip to Content
Merck
CN

Key Documents

View All Documentation

441562

trans-1-Acetyl-4-hydroxy-L-proline

≥98%, for peptide synthesis

Synonym(s):

N-Acetyl-L-hydroxyproline

Sign In to View Organizational & Contract Pricing.

Select a Size

Change View

About This Item

Empirical Formula (Hill Notation):
C7H11NO4
CAS Number:
33996-33-7
Molecular Weight:
173.17
NACRES:
NA.22
PubChem Substance ID:
24867668
eCl@ss:
32160406
UNSPSC Code:
12352209
EC Number:
251-780-6
MDL number:
MFCD00037339
Beilstein/REAXYS Number:
84043
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

Product Name

trans-1-Acetyl-4-hydroxy-L-proline, ≥98%

Quality Segment

100

assay

≥98%

form

powder

optical activity

[α]20/D −119°, c = 4 in H2O

reaction suitability

reaction type: solution phase peptide synthesis

mp

132-133 °C (dec.) (lit.)

application(s)

peptide synthesis

SMILES string

CC(=O)N1C[C@H](O)C[C@H]1C(O)=O

InChI

1S/C7H11NO4/c1-4(9)8-3-5(10)2-6(8)7(11)12/h5-6,10H,2-3H2,1H3,(H,11,12)/t5-,6+/m1/s1

InChI key

BAPRUDZDYCKSOQ-RITPCOANSA-N

Application

trans-1-Acetyl-4-hydroxy-L-proline can be used:
  • In the stereospecific synthesis of 4-fluoroglutamic acid.
  • To synthesize molecular targets for von Hippel-Lindau (VHL) E3 ubiquitin ligase.
  • As a precursor to synthesize pseudopoly(amino acids) such as poly(trans-4-hydroxy-4-acyl-L-proline ester) and a biodegradable polymer, poly(lactic acid-glycolic acid-4-hydroxyproline).

pictograms

Corrosion
GHS05

signalword

Danger

hcodes

H318

Hazard Classifications

Eye Dam. 1

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library